Frühere/Ergebnisse
Frühere/Ergebnisse
Frühere/Ergebnisse
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
((3-(sec-butyl)-4-(decyloxy)phenyl)methanetriyl)tribenzene | 801-941-7 | 1404190-37-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
20/10/2016 20/10/2016 |
05/12/2016 05/12/2016 |
Details | |
((3-(sec-butyl)-4-(decyloxy)phenyl)methanetriyl)tribenzene | 801-941-7 | 1404190-37-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2016 31/05/2016 |
15/07/2016 15/07/2016 |
Details | |
(-)-pin-2(3)-ene | 232-077-3 | 7785-26-4 | Reproductive toxicity (pre-natal developmental toxicity) | 25/10/2017 | 11/12/2017 | Details | |
(1,4-diazabicyclo[2.2.2]octane-2-yl)methanol | 692-731-2 | 76950-43-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/02/2015 16/02/2015 |
02/04/2015 02/04/2015 |
Details | |
(1-hydroxycyclohexyl) (phenyl)methanone (hydroxycyclohexyl phenyl ketone) | 213-426-9 | 947-19-3 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
28/02/2011 28/02/2011 28/02/2011 |
14/04/2011 14/04/2011 14/04/2011 |
Details | |
(1-methylethylidene)di-4,1-phenylene tetraphenyl diphosphate,Bisphenol A Diphosphate,Bisphenol A Polyphosphate | 425-220-8 | 5945-33-5 | Reproductive toxicity (two-generation reproductive toxicity) | 05/04/2011 | 20/05/2011 | Details | |
(1-methylethylidene)di-4,1-phenylene tetraphenyl diphosphate,Bisphenol A Diphosphate,Bisphenol A Polyphosphate | 425-220-8 | 5945-33-5 | Sub-chronic toxicity (90-day): oral | 01/09/2010 | 15/10/2010 | Details | |
(1-methylethylidene)di-4,1-phenylenetetraphenyl diphosphate | 425-220-8 | 5945-33-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
26/08/2021 26/08/2021 |
11/10/2021 11/10/2021 |
Details | |
(1S)-1,5-anhydro-2,3,4,6-tetrakis-O-(2,2-dimethylpropanoyl)-1-(3-{[5-(4-fluorophenyl)-2-thienyl]methyl}-4-methylphenyl)-D-glucitol | 695-878-0 | 1283129-18-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
24/02/2020 24/02/2020 |
09/04/2020 09/04/2020 |
Details | |
(2,4,6-trioxo-1,3,5-triazine-1,3,5(2H,4H,6H)-triyl)tri-2,1-ethanediyl triacrylate | 254-843-6 | 40220-08-4 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 19/10/2020 | 03/12/2020 | Details | |
(2-ethyl-2-methyl-1,3-dioxolan-4-yl)methyl prop-2-enoate | 807-159-2 | 69701-99-1 | Genetic toxicity in vivo | 26/10/2022 | 12/12/2022 | Details | |
(2E)-2-ethyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)but-2-en-1-ol | 701-122-3 | 106185-75-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
26/10/2022 26/10/2022 |
12/12/2022 12/12/2022 |
Details | |
(3-chloropropyl)diethoxymethylsilane | 236-828-6 | 13501-76-3 | Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposed with (3-chloropropyl)triethoxysilane (CAS 5089-70-3) | 17/04/2015 | 04/06/2015 | Details | |
(3-chloropropyl)dimethoxymethylsilane | 242-056-0 | 18171-19-2 | Sub-chronic toxicity (90-day): oral | 25/05/2020 | 09/07/2020 | Details | |
(3-chloropropyl)dimethoxymethylsilane | 242-056-0 | 18171-19-2 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with (3-chloropropyl)triethoxysilane (EC 225-805-6)” | 17/04/2015 | 04/06/2015 | Details | |
(3-chloropropyl)triethoxysilane | 225-805-6 | 5089-70-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
26/10/2022 26/10/2022 |
12/12/2022 12/12/2022 |
Details | |
(3E)-2-chloro-3-(hydroxymethylene)cyclohexene-1-carbaldehyde | 801-656-8 | 1416808-92-8 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 17/04/2015 | 04/06/2015 | Details | |
(5-ethyl-1,3-dioxan-5-yl)methyl acrylate | 266-380-7 | 66492-51-1 | Reproductive toxicity (pre-natal developmental toxicity) | 21/03/2014 | 05/05/2014 | Details | |
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | 261-491-7 | 58909-56-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
10/08/2018 10/08/2018 10/08/2018 |
24/09/2018 24/09/2018 24/09/2018 |
Details | |
(chloromethyl)triethoxysilane | 239-311-3 | 15267-95-5 | Genetic toxicity in vivo | 16/10/2014 | 01/12/2014 | Details | |
(E)-1,1,1,2,3,4,5,5,5-Nonafluoro-4-(trifluoromethyl)pent-2-ene | 807-113-1 | 3709-71-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation |
19/10/2020 19/10/2020 |
03/12/2020 03/12/2020 |
Details | |
(E)-2-benzylideneoctanal | 639-566-4 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
15/04/2011 15/04/2011 |
30/05/2011 30/05/2011 |
Details | |
(E)-7,11-dimethyl-3-methylenedodeca-1,6,10-triene | 242-582-0 | 18794-84-8 | Sub-chronic toxicity (90-day): oral | 23/04/2018 | 07/06/2018 | Details | |
(E)-N-(pentan-2-ylidene)hydroxylamine | 484-470-6 | 623-40-5 | Reproductive toxicity (pre-natal developmental toxicity) | 18/03/2021 | 03/05/2021 | Details | |
(ethoxymethoxy)cyclododecane | 261-332-1 | 58567-11-6 | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
(octadecanoato-O)oxoaluminium | 236-521-7 | 13419-15-3 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Aluminum, benzoate C16-18 fatty acid complexes (CAS 94166-87-7) | 30/11/2015 | 14/01/2016 | Details | |
(octahydro-4,7-methano-1H-indenediyl)bis(methylene) diacrylate | 255-901-3 | 42594-17-2 |
Bioaccumulation test (Bioconcentration: Flow-through Fish Test) Reproductive toxicity (pre-natal developmental toxicity) |
23/03/2020 23/03/2020 |
07/05/2020 07/05/2020 |
Details | |
(octahydro-4,7-methano-1H-indenediyl)bis(methylene) diacrylate | 255-901-3 | 42594-17-2 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
22/04/2021 22/04/2021 22/04/2021 |
07/06/2021 07/06/2021 07/06/2021 |
Details | |
(octahydro-4,7-methano-1H-indenyl)methyl acrylate | 300-723-4 | 93962-84-6 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 23/11/2020 | 07/01/2021 | Details | |
(phenylethyl)benzene | 254-179-7 | 38888-98-1 | Reproductive toxicity (pre-natal developmental toxicity) | 21/03/2014 | 05/05/2014 | Details | |
(R)-p-mentha-1,8-diene | 227-813-5 | 5989-27-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/05/2020 | 09/07/2020 | Details | |
(Reaction product of 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol, 2-(2-hydroxyethylamino)ethanol and formaldehyde), propoxylated | 926-000-9 | - | Reproductive toxicity (pre-natal developmental toxicity) | 04/04/2014 | 19/05/2014 | Details | |
(Z)-4-[C11-13 (branched) alkylamino]-4-oxo-2-butenoic acid | 701-116-0 | - | Reproductive toxicity (pre-natal developmental toxicity) | 23/03/2020 | 07/05/2020 | Details | |
(Z)-4-[C11-13(branched)alkylamino]-4-oxo-2-butenoic acid | 701-116-0 | 84583-68-6 | Sub-chronic toxicity (90-day): oral || Note: The previous EC number for the substance is 283-219-6. | 22/06/2017 | 07/08/2017 | Details | |
(Z)-N-octadec-9-enylhexadecan-1-amide | 240-367-6 | 16260-09-6 | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
1,1'-(1,1,2,2-tetramethylethylene)dibenzene | 217-568-2 | 1889-67-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
1,1'-(ethane-1,2-diyl)bis[pentabromobenzene] | 284-366-9 | 84852-53-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 24/02/2020 | 09/04/2020 | Details | |
1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromo-2-methylpropoxy)benzene] | 306-832-3 | 97416-84-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
01/07/2021 01/07/2021 |
16/08/2021 16/08/2021 |
Details | |
1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromopropoxy)benzene] | 244-617-5 | 21850-44-2 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 |
Details | |
1,1'-(methylenedi-p-phenylene)bismaleimide | 237-163-4 | 13676-54-5 | Reproductive toxicity (pre-natal developmental toxicity) | 30/09/2021 | 15/11/2021 | Details | |
1,1'-(p-tolylimino)dipropan-2-ol | 254-075-1 | 38668-48-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/03/2016 17/04/2015 |
28/04/2016 04/06/2015 |
Details | |
1,1'-[[3-(dimethylamino)propyl]imino]bispropan-2-ol | 264-261-4 | 63469-23-8 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
27/01/2020 27/01/2020 |
12/03/2020 12/03/2020 |
Details | |
1,1'-[[3-(dimethylamino)propyl]imino]bispropan-2-ol | 264-261-4 | 63469-23-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
22/09/2022 22/09/2022 |
07/11/2022 07/11/2022 |
Details | |
1,1'-[oxybis(ethyleneoxy)]diethylene | 212-133-3 | 764-99-8 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
01/03/2023 01/03/2023 |
17/04/2023 17/04/2023 |
Details | |
1,1'-dithiobis[hexahydro-2H-azepin-2-one] | 245-910-0 | 23847-08-7 | Reproductive toxicity (pre-natal developmental toxicity) | 25/06/2015 | 10/08/2015 | Details | |
1,1'-isopropylidenebis(p-phenyleneoxy)dipropan-2-ol | 204-137-9 | 116-37-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/03/2018 | 11/05/2018 | Details | |
1,1'-isopropylidenebis(p-phenyleneoxy)dipropan-2-ol | 204-137-9 | - |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/01/2012 16/01/2012 16/01/2012 |
01/03/2012 01/03/2012 01/03/2012 |
Details | |
1,1'-isopropylidenebis(p-phenyleneoxy)dipropan-2-ol | 204-137-9 | 116-37-0 | Reproductive toxicity (pre-natal developmental toxicity) | 31/07/2015 | 14/09/2015 | Details | |
1,1'-Methylenebis(4-isocyanatobenzene) and 1,1'-methylenebis(4-isocyanatobenzene) homopolymer and their reaction products with [(methylethylene)bis(oxy)]dipropanol and butane-1,3-diol and propane-1,2-diol | 701-393-8 | - | Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) | 16/06/2022 | 01/08/2022 | Details | |
1,1'-Methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with [(methylethylene)bis(oxy)]dipropanol | 701-124-4 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) | 01/04/2022 | 16/05/2022 | Details | |