Support by accredited stakeholders

This page offers web links to tools, information and guidance that are publically available and free of charge. They have been provided by ECHA's accredited stakeholders, and are published with the aim to facilitate the implementation of European chemicals legislation.

Linking to other websites should not be taken as an endorsement of any kind by ECHA. If you access another site through one of these links you are subject to the privacy policy of that site. For further information see ECHA's Legal Notice.

International Association for Soaps, Detergents and Maintenance Products
REACH implementation and communication support
European Chemical Industry Council
European Council of the Paint, Printing Ink and Artists' Colours Industry
Use descriptors, risk management measures and specific environmental release categories
International Chemical Secretariat
Support for the substitution of hazardous chemicals
Conservation of Clean Air and Water in Europe
European Centre for Ecotoxicology and Toxicology of Chemicals
Tool for worker exposure assessment models
European Copper Institute
European Crop Protection Association
Tools for REACH requirements in plant protection
The international association for the nonwovens and related industries
Association of European ferro-Alloy producers
Information for ferro-alloys and silicon producers
The European Steel Association
REACH information, helpdesk and data sharing forum
European Association of Metals
REACH and CLP support
European Aerosol Federation
Tool to predict indoor aerosol concentration
European Association of Chemical Distributors
Safety, Health and Environment Committee
Association of European Adhesives and Sealants Manufacturers
Use descriptors
Nanotechnology Industries Association
Nano safety assessment projects
Peta International Science Consortium, Ltd.
Webinar 1: OECD QSAR toolbox and read-across
October 22, 2014 11am -12:15pm Eastern Time
Grace Patlewicz, DuPont
Mark Cronin, Liverpool John Moores University
Drs Cronin and Patlewicz will briefly discuss the use of integrated approaches to testing and assessment and adverse outcome pathways to organize existing information and plan a non-animal testing strategy. Specifically, they will discuss how QSARs and read-across can be used to meet REACH requirements and will detail the use of the OECD QSAR Toolbox. There will also be a discussion of future research projects.


Webinar 2: Skin irritation and corrosion
November 11, 2014
11am -12:00pm Eastern Time
Gertrude-Emilia Costin, Institute for In Vitro Sciences
Costanza Rovida, CAAT Europe and REACH Mastery
Dr Costin will describe the in vitro methods that can be used to meet REACH data requirements for skin irritation and corrosion under Annexes VII and VIII. Dr Rovida will explain how the in vitro methods can be used in an integrated approach to testing and assessment using specific examples.


Webinar 3: Serious eye damage and eye irritation
December 4, 2014
4pm - 5:30pm GMT
Kim Norman, Institute for In Vitro Sciences
João Barroso, EURL ECVAM
Drs Norman and Barroso will first discuss the drivers of in vivo classification for serious eye damage and eye irritation in order to define what is required to achieve full replacement of the regulatory animal test. Then, the available in vitro methods and how they can be used alone or in combination in testing strategies such as the top-down or bottom-up approaches, will be described.


Webinar 4: Skin sensitisation
January 28, 2015
11am - 12pm US EST       4pm - 5pm GMT
Dr Susanne Kolle, BASF SE Silvia Casati, EURL ECVAM
Dr Kolle will first discuss data requirements and in vivo classification for skin sensitisation in order to define what is required to replace the animal test. Dr Casati will provide an overview of the key mechanism of skin sensitisation, based on the published adverse outcome pathway, and describe the in vitro and in chemico methods that can be used to assess skin sensitisation with a specific focus on the validated methods. Dr Kolle will then discuss examples of how these methods can be combined in testing strategies/integrated approaches. She will also present how each method (or their combination) perform for "real life" substances, as well as specific case studies for read-across approaches, and how the methods can be applied for REACH. Dr Casati will close by reviewing current OECD activities in the field of skin sensitisation.


Webinar 5: Alternative approaches to Mammalian Acute Systemic Toxicity Testing
March 5, 2015
11am - 12pm US EST      4pm - 5pm GMT
Dr Pilar Prieto, EURL ECVAM Dr Lawrence Milchak, 3M
Dr Pilar Prieto will present on EURL ECVAM's recently released strategy to replace, reduce and refine the use of animals in the assessment of acute mammalian systemic toxicity. The strategy highlights the importance of developing adverse outcome pathways (AOPs) and integrated approaches to testing and assessment (IATA) related to acute systemic toxicity. It also discusses improvements in the predictability of the 3T3 NRU assay, development of additional in vitro and in silico approaches, waiving acute toxicity testing based on e.g., repeated dose data, refinement of in vivo studies, and provides a framework for prioritising the alternative methods that have been submitted to EURL ECVAM for validation. Following Dr Prieto's talk, Dr Lawrence Milchak from 3M will speak to industry experiences on the use of alternative strategies to meet acute toxicity testing requirements.


Webinar 6: (Zebra)Fish Embryo Acute Toxicity Test to predict short term toxicity to fish (and beyond)
April 14, 2015
11am - 12pm US EST      4pm - 5pm GMT
Marlies Halder, EURL ECVAM Thomas Braunbeck, Unviersity of Heidelberg Scott Belanger, Procter & Gamble
In this webinar, Dr Halder will begin by describing the REACH data requirements for short term toxicity testing on fish and the OECD acute fish toxicity test (OECD TG 203). She will then describe the Fish Embryo Acute Toxicity Test (FET), which was adopted by the OECD in 2013 as Test Guideline 236 and is recommended by the European Union Reference Laboratory for Alternatives to Animal Testing as a possible alternative to the acute fish toxicity test. Dr Belanger will provide an assessment of the correlation between the OECD acute fish toxicity test and the fish embryo toxicity test. This will include an assessment of the domain of applicability and the possibility of using the FET in traditional fish Quantitative Structure Activity Relationships.  Prof. Braunbeck will then describe the potential use of fish embryos beyond acute fish toxicity testing and provide a view to potential future uses of fish embryos in a much wider array of environmental science and human health applications.



Webinar 7: The Regulatory Processes Involved in Acceptance of Non-Animal Tests
10 June, 2015
3pm - 4pm BST
Derek Knight, ECHA and Karin Kilian, European Commission
Derek Knight, Senior Scientific Advisor, ECHA, will speak about regulatory acceptance from a scientific and procedural point of view. Karin Kilian, Policy Officer, European Commission, DG ENVIRONMENT,Unit A.3, Chemicals, will explain the process for incorporating validated tests into the EU Test Methods Regulation. She will also give a brief history of it and how it relates to REACH/CLP and other EU chemicals laws. Finally, she will present a timeline for updates of the Regulation.


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