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Comprehensive toxicological profiles for several selected chemical substances. Including information on uses, effects and exposure.

BREFs or ‘BAT reference documents’ are documents resulting from the exchange of information organised pursuant to Article 13 of Industrial Emissions Directive (IED, 2010/75/EU). BREFs provide information for specific industrial/agricultural sectors on
-the processes and applied techniques used in the sector
-current emissions and consumption levels
-techniques considered for the determination of the best available techniques (BAT)
-‘BAT conclusions’ and any emerging techniques.

‘BAT conclusions’ are the key element of the BREFs and lay down the conclusions on best available techniques, their description, information to assess their applicability, the emission levels associated with the BAT, associated monitoring, associated consumption levels and, where appropriate, relevant site remediation measures.
In accordance with Article 14(3) of Directive 2010/75/EU, BAT conclusions shall be the reference for setting permit conditions for installations covered by the Directive.
The IED replaces the IPPC Directive and other sectorial directives as of 7 January 2014. The full list of the BREFs adopted by the European Commission can be downloaded from the website of the European IPPC Bureau.

It provides access to various databases containing information on the occurrence of cancer worldwide held and managed by the Section of Cancer Information (CIN) of IARC.

International Information System on Occupational Exposure to Carcinogens.

Meta-database displaying results on chemicals from INCHEM, ILO, SDS, and Canadian legislation

Catalogue of examples of substitution of hazardous chemicals – case studies

General overview of the chemicals industry in the EU with information on employment, growth, cost, prices, energy, international trade, R&D.

Several publications on the externalities of energy

Database of suppliers of chemical substances

Reports on chemical substances with information on manufacture and global trade. Free abstracts available.

Database of suppliers; search by country available

Risk management tools that target CEPA-toxic substances (as defined in the Canadian Environmental Protection Act, 1999, CEPA 1999) or other chemical substances.

Search engine producing results on manufacturers and suppliers of chemicals and background information on substances

CleanerSolutions Tool is field-searchable by contaminants, substrates, equipment, solvents replaced and vendor product data. The goal is to assist in the search for safer cleaning processes by identifying, developing and promoting safer alternatives to hazardous solvents.

Economic Assessment of Environment and Resource Costs in the Water Framework Directive (AquaMoney). Case studies available.

Key reports on: economic valuation of biodiversity and ecosystem services, analysis and guidance on how to value and internalize biodiversity and ecosystem values in policy decisions; analysis and guidance for mainstreaming biodiversity and ecosystem values at regional and local levels.

Network of reference laboratories, research centres and related organisations for monitoring of emerging environmental substances. It organises the development and maintenance of two web-based databases:
EMPODAT: a database of geo-referenced monitoring / occurrence data on emerging substances;
NORMAN MassBank: a database of mass spectra of unknown or provisionally identified substances.

It provides several models:
CAFE-CBA (air quality): used to assess the benefits of the Thematic Strategy for Air Pollution
GEM-E3 : used to assess the impact of post-Kyoto climate policies of the EU.

Collection of environmental valuation studies presented in an on-line database. Useful for incorporating environmental values into cost-benefit analyses

Espacenet offers free access to more than 80 million patent documents worldwide, containing information about inventions and technical developments from 1836 to today.

Includes several publications of relevance to chemicals.

The final report provides information on the competitiveness of the European Chemicals Industry related to innovation & research, regulation, human resources, energy & feedstock, climate change policy, logistics, globalisation, international competitiveness and trade.

The study includes a database providing an overview of existing techniques to assess social and employment impacts.

EU Exposure Assessment Toolbox is a reference system for Exposure Scenarios that have been applied in risk assessments at world scale

The European Pollutant Release and Transfer Register (E-PRTR) is a web-based register established by Regulation (EC) No 166/2006 which implements the UNECE PRTR Protocol, signed in May 2003 in Kiev.

European business - facts and figures is a set of articles providing a comprehensive picture of the structure and characteristics of the European business economy. The articles are updated regularly.

Annual waste, land use, climate change, air, water, energy price and main sector indicator data

Production value (€) and quantity sold or exported/imported by Member States in the EU by manufactured product

This Eurostat study (2009) developed a baseline of the risk caused by chemicals and a set of indicators to monitor the implementation of REACH. The proposed indicator system also enables changes in the quality of the public data on substances and their safe use to be detected.

Annually produced general enterprise and trade statistics in the EU (e.g. number, size, turnover) by sector (NACE code.
Access to annual enterprise statistics.
Annual structural business statistics are available as part of the industry, trade and services domain.

Data on the number of accidents at work in the EU. Data can be selected according to economic activity, severity, type of injury, size of enterprise, employment status.

The European Exposure Factors (ExpoFacts) Sourcebook is a tool for environmental exposure analysis and risk assessment.
European exposure factor data, statistics and references from national and international institutes, scientific articles and reports have been compiled into the ExpoFacts database.

“ExternE-Methodology” is an approach for calculating environmental external costs

Methodology for calculating externalities.

It provides various links to studies, workshops, conferences covering safety and health issues.

The Technical Rules for Hazardous Substances (TRGS) reflect the state of technology, occupational safety and health and occupational hygiene as well as other definite knowledge relating to activities involving hazardous substances including their classification and labelling.

Database (in German) of hazardous substances. Also GHS converter and a register of hazardous materials

Search engine for books, excerpts occasionally available

HEATCO's primary objective was the development of harmonised guidelines for project assessment for trans-national projects in Europe. It also covers: value of changes in accident risks, environmental costs (incl. air pollution, noise, global warming).

Database searchable by several categories, such as hazardous agents, occupational diseases, high risk jobs, etc.

IOMLIFET is a free source spreadsheet system for life-table calculations in the context of health impact assessments. It can be used for predictions of the patterns of mortality and life expectancy.

Database by the US Department of Health and Human Services

European voluntary initiative launched in 1999 by A.I.S.E. and Cefic.

Provides a common risk assessment framework for the household cleaning products industry.

Risk assessment reports available for several chemical substances and groups of substances

The new Encyclopedia website is a cutting-edge global knowledge platform for sharing occupational safety and health (OSH) information and good practices.

The International Hazard Datasheets on Occupations is a multipurpose information resource containing information on the hazards, risks and notions of prevention related to a specific occupation.

Chemical Safety Information from Intergovernmental Organizations

Includes information on sources, transport, hazards, exposure.

HSGs for some chemical substances (focus on prevention/protection methods)

List of summaries and evaluations by IARC

PIMs for several chemical substances (includes information on identity, uses, exposure, toxicology, clinical effects, management)

Comprehensive reports on several chemical substances (information on identity, properties, uses, effects and exposure, risks and testing results)

(Info available under about INRS>at your service) Institute National de Recherche et de securite can provide information (in French) concerning levels of exposure to chemicals by business sector or by work station. Data is taken from the COLCHIC database that has 500,000 exposure measurement reports on 1,000 substances.<br/>
INRS also manages the EPICEA database (in French) of occupational accident investigation reports. This database is used to obtain data concerning severe or fatal accidents by activity branch or by cause of accident.

This impact assessment from 2007 assesses the impacts (mainly social and economic) of policy options related to the standardisation of the use of legal units of measurement within the EU.

Assessment of economic, environmental and social impacts of Commission policy proposals. The impacts assessments that are planned and carried out are listed per year.

This impact assessment (2007) concerns the implementation of the Globally Harmonised System of classification and labelling of substances and mixtures (GHS) in the EU through a proposed Regulation and its consequential changes to other related Community Legislation on chemicals (downstream legislation). It provides information on human health & environment, direct economic costs and benefits for companies, effects on trade & external competitiveness, social impacts & effects on employment, effects on developing countries and effects on SMEs.

This impact assessment (2005) analyses the environmental, economic and social impacts of a number of policy options to inform the development of the Community Strategy Concerning Mercury.

This impact assessment (2008) analyses the environmental, economic and social impact of the proposal for a Directive of the European Parliament and of the council amending Directive 88/378/EEC on the safety of toys. It provides an analysis of the problems that have been identified in the functioning of the current provisions. It identifies the objectives to respond to these problems, and most importantly the policy options that have been considered to translate these objectives into new legislative measures.

Search engine for articles, journals, reports

This Toolbox is designed to help people design and carry out integrated environmental health impact assessments.

Risk assessment documents on several chemical substances

Swedish Chemicals Agency databases.

Database of suppliers; also database of companies within specific industry sectors

The study contains an analysis of the damage costs of continuing mercury pollution without any further measures until 2020. The analysis has mainly focussed on IQ losses due to the exposure to methyl mercury via ingestion of contaminated fish. Other human health, social and environmental damages are also discussed as are costs of controlling mercury emissions. Furthermore, societal benefits of reducing mercury emissions are presented for two emission reduction scenarios.

The Division of Cancer Epidemiology and Genetics (DCEG) is a research program of the National Cancer Institute (NCI). The Division is the world’s most comprehensive cancer epidemiology research group. Search engine available.

Links to statistics offices and authorities of UNECE member countries

It provides reports on chemical agents.

SDS and product data from the Norwegian register

Documents that describe the sources, production processes, pathways and use patterns with the aim of quantifying the emissions (or releases) of a chemical into water, air, soil and/or solid waste. Available for several sectors/types of processes.

This database tracks all chemicals in the OECD cooperative Chemicals Assessment Programme, including High production volume (HPV) chemicals. The database contains any annotations on each chemical provided to the Secretariat by member countries.

It provides several documents to promote and facilitate the integration of SEA in chemical risk management decision-making.

eChemPortal provides free public access to information on properties of chemicals:
- Physical Chemical Properties
- Environmental fate and behaviour;
- Ecotoxicity;
- Toxicity

It provides several studies. Among others: Valuation of Environment-Related Health Risks for Children, Cost-Benefit Analysis and the Environment: Recent Developments.

Europe-wide database for parts cleaning, metal surface cleaning, component cleaning and degreasing, based on real processes in numerous European companies

Past impact assessments, evaluations and studies on a variety of different sectors

Industry news and articles on polymer additives

Service of the U.S. National Library of Medicine that includes over 18 million citations from MEDLINE and other life science journals for biomedical articles back to the 1950s. Includes links to full text articles and other related resources.

Reports on agents, substances, mixtures, or exposure circumstances that may pose a hazard to human health by virtue of their carcinogenicity. Published biennially by the National Toxicology Program (US Department of human health)

Database on occupational exposure to solvents used in the workplace

Search engine for journal articles.

Detailed information on more than 11,200 chemicals, including all the chemicals used in large amounts in the United States and all the chemicals regulated under major environmental laws

This site provides details of the Sickness Absence Reporting Tool (SART) development project carried out by the Institute of Occupational Medicine (IOM) for the UK Health and Safety Executive (HSE), and subsequent developments

Tool for reviewing and comparing solvent hazards (in French)

Information on Priority Substances, including uses and alternatives

News, articles, technical papers and chemical databases for polymer additives, plastics and elastomers, coatings and inks, adhesives and sealants, and cosmetics

Database on the use of chemicals in the Nordic countries. Tonnages per country and area of application (NACE) provided

Final Report on substitution of hazardous chemicals

It provides databases covering toxicology, genomics, risk assessment, animal testing alternatives, breastfeeding and drugs, etc.

Reports and fact sheets. Subjects include alternatives assessment for hazardous materials, environmental management, safer technologies, and toxic chemical facts.

Studies on substitution of chemicals and good practice in industrial sectors

Statistical information on ill health, accidents and working days lost.

Comparable data for Europe, North America and Central Asia
Economic, gender, employment statistics

Information on identity of POPs, monitoring data and alternatives

This handbook provides an introductory survey of the theory, techniques, and existing literature pertaining to economic valuation of non-cancer health effects.

The High Production Volume Information System (HPVIS) is a database that provides access to health and environmental effects information on chemicals produced or imported in the United States in the greatest quantities, obtained through the High Production Volume (HPV) Challenge Program.

Robust Summaries for several chemicals are available .

Questions were used to investigate people's tastes for cancer risk reductions in the context of public programs that would provide for remediation at abandoned industrial contaminated sites.

The WHO Global Health Estimates provide a comprehensive and comparable assessment of mortality and loss of health due to diseases and injuries for all regions of the world. Due to changes in data and some methods, the 2000–2012 estimates are not comparable to previously-released WHO estimates.

Background document on the scientific aspects of endocrine disruption

Some case studies, examples and tools on substitution are available

Background document on the susceptibilities, exposure and methodologies to assess health outcomes in children.

WHO's annual World Health Statistics reports present the most recent health statistics for the WHO Member States.

This web portal forwards to websites with focus on information relevant for the implementation of the European Water Framework Directive (WFD).

Integrated hydro-economic model for the Netherlands. The model predicts the direct and indirect economic impacts of policy measures and instruments at national and river basin level.

It provides surveillance data on occupationally-related respiratory diseases, and for many of these diseases selected data on related exposures are presented.