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Ecotoxicological information

Long-term toxicity to fish

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Administrative data

Endpoint:
adult fish: sub(lethal) effects
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Acceptable, well documented publication which meets basic scientific principles

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Quantitative structure-activity relationships for Kinetics and Toxicity of Aquatic Pollutants and their Mixtures in Fish
Author:
Koenemann WH
Year:
1979
Bibliographic source:
Thesis University of Utrecht, NL
Reference Type:
publication
Title:
Quantitative structure-activity relationships in fish toxicity studies
Author:
Koenemann H
Year:
1981
Bibliographic source:
Toxicology 19, 209-221

Materials and methods

Test guideline
Qualifier:
equivalent or similar to
Guideline:
OECD Guideline 204 (Fish, Prolonged Toxicity Test: 14-day Study)
Deviations:
yes
Remarks:
: no purity given, no analytical monitoring, solvent used amount not specified, water quality monitoring not detailed, control data missing
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
No purity stated

Sampling and analysis

Analytical monitoring:
not specified

Test solutions

Vehicle:
yes
Details on test solutions:
Acetone or Propanol-2

Test organisms

Test organisms (species):
Poecilia reticulata
Details on test organisms:
2-3 mounth old fish

Study design

Test type:
semi-static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
14 d

Test conditions

Hardness:
25 mg CaCO3/L
Test temperature:
22°C +/- 1°C
Dissolved oxygen:
>5 mg/L
Details on test conditions:
- 1 L standard water in 1.5 L vessel
- 8 guppies/concentration
- water renewed daily
Reference substance (positive control):
no

Results and discussion

Effect concentrations
Duration:
14 d
Dose descriptor:
LC50
Effect conc.:
2.3 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: results in the publication are given as log LC50 and in [µmol/L]

Applicant's summary and conclusion