Registration Dossier
Registration Dossier
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EC number: 201-757-1 | CAS number: 87-61-6
Toxicity to microorganisms
Administrative data
- Endpoint:
- activated sludge nitrification inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- A database of chemical toxicity to environmental bacteria and ist use in interspecies comparisons and correlations
- Author:
- Blum DJW and RE Speece
- Year:
- 1 991
- Bibliographic source:
- Research Journal WPCF 63(3): 198-207
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- ISO 9509 (Toxicity test for assessing the inhibition of nitrification of activated sludge microorganisms)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 1,2,3-trichlorobenzene
- EC Number:
- 201-757-1
- EC Name:
- 1,2,3-trichlorobenzene
- Cas Number:
- 87-61-6
- Molecular formula:
- C6H3Cl3
- IUPAC Name:
- 1,2,3-trichlorobenzene
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test solutions
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- Nitrosomonas sp.
Study design
- Test type:
- not specified
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 24 h
Test conditions
- Test temperature:
- 25°C
- pH:
- 6.5-8.0
- Details on test conditions:
- - Test vessel: 125 mL serum bottle
- Liquid Volume: 50 mL
- Shaking: yes
Results and discussion
Effect concentrations
- Duration:
- 24 h
- Dose descriptor:
- IC50
- Effect conc.:
- 96 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- other: Ammonia use
Applicant's summary and conclusion
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