[Confidential]
|
-
|
-
|
-
|
((2R,3R,4R,5R)-3-(benzoyloxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-4-methyltetrahydrofuran-2-yl)methyl benzoate
|
807-766-2
|
863329-65-1
|
-
|
View substance registered dossier
|
Yordas GmbH
|
Äuβere Nürnberger Straβe 62 91301 Forchheim Germany
|
Germany
|
Cease Manufacture
|
((4S,4aR,7S,7aR)-4,7-dimethylhexahydrocyclopenta[c]pyran-1(3H)-one
|
953-513-5
|
-
|
2023
|
View substance registered dossier
|
Sicor - Società Italiana Corticosteroidi S.r.l.
|
Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy
|
Italy
|
Cease Manufacture
|
(+)-2-amino-1-butanol
|
227-475-9
|
5856-62-2
|
2022
|
View substance registered dossier
|
Janssen Pharmaceutica N.V.
|
Turnhoutseweg 30 2340 Beerse Belgium
|
Belgium
|
Cease Manufacture
|
(+-)-2,4-dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
|
607-685-0
|
252964-68-4
|
2021
|
View substance registered dossier
|
Janssen Pharmaceutica N.V.
|
Turnhoutseweg 30 2340 Beerse Belgium
|
Belgium
|
Cease Manufacture
|
(+-)-TRANS-3-METHYL-1-[(4-METHYLPHENYL)SULFONYL]-4-PHENYLPIPERIDINE-4-CARBONITRILE
|
607-821-9
|
25858-24-6
|
2020
|
View substance registered dossier
|
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority.
|
-
|
-
|
No longer Valid
|
(+/-) tetrahydrofurfuryl (R)-2-[4-(6-chloroquinoxalin-2-yloxy)phenyloxy]propionate
|
414-200-4
|
200509-41-7
|
2022
|
View substance registered dossier
|
ESIM Chemicals GmbH
|
St.-Peter-Strasse 25 4020 Linz Austria
|
Austria
|
Cease Manufacture
|
(+/-) tetrahydrofurfuryl (R)-2-[4-(6-chloroquinoxalin-2-yloxy)phenyloxy]propionate
|
414-200-4
|
200509-41-7
|
2022
|
View substance registered dossier
|
Janssen Pharmaceutica N.V.
|
Turnhoutseweg 30 2340 Beerse Belgium
|
Belgium
|
Cease Manufacture
|
(+/-)-(R*,S*)-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran
|
419-630-6
|
793669-26-8
|
2017
|
View substance registered dossier
|
Merck KGaA
|
Frankfurter Strasse 250 64293 Darmstadt Germany
|
Germany
|
Cease Manufacture
|
(+/-)-(R*,S*)-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran
|
419-630-6
|
793669-26-8
|
2023
|
View substance registered dossier
|
Janssen Pharmaceutica N.V.
|
Turnhoutseweg 30 2340 Beerse Belgium
|
Belgium
|
Cease Manufacture
|
(+/-)-[(R*,R*)and(R*,S*)]-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran
|
419-600-2
|
99199-90-3
|
2017
|
View substance registered dossier
|
OLON Spa
|
Strada Rivoltana Km 6/7 20053 RODANO Milano Italy
|
Italy
|
Cease Manufacture
|
(1-chlorocyclohexyl) cyclohexyl ketone
|
280-893-3
|
83803-75-2
|
2022
|
View substance registered dossier
|
[Confidential]
|
-
|
-
|
-
|
(1-ethoxy-1-oxopropan-2-yl) 5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrobenzoate
|
616-466-9
|
77501-63-4
|
-
|
View substance registered dossier
|
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED
|
Regus Harcourt Centre D02 HW77 Dublin Ireland
|
Ireland
|
Cease Manufacture
|
(1-methylethylidene)di-4,1-phenylenetetraphenyl diphosphate
|
425-220-8
|
5945-33-5
|
2014
|
View substance registered dossier
|
OLON Spa
|
Strada Rivoltana Km 6/7 20053 RODANO Milano Italy
|
Italy
|
Cease Manufacture
|
(10aS)-methyl 10a-methoxy-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylate
|
607-239-5
|
23495-64-9
|
2022
|
View substance registered dossier
|
[Confidential]
|
-
|
-
|
-
|
(10S)-10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
|
810-248-9
|
104746-04-5
|
-
|
View substance registered dossier
|
Bayer AG
|
Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany
|
Germany
|
Cease Manufacture
|
(17α)-17-hydroxy-3-oxoandrost-4-ene-17-carbonitrile
|
278-780-9
|
77881-13-1
|
2022
|
View substance registered dossier
|
Minakem Dunkerque Production
|
224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France
|
France
|
Cease Manufacture
|
(1E)-N-hydroxy-1-(naphthalen-1-yl)ethanimine
|
700-765-7
|
100485-51-6
|
2019
|
View substance registered dossier
|
REACH COMPLIANCE SERVICES LIMITED
|
Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
|
Ireland
|
Cease Manufacture
|
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
|
413-110-2
|
135861-56-2
|
2021
|
View substance registered dossier
|
ROQUETTE Frères
|
1 rue de la haute loge 62136 LESTREM Cedex France
|
France
|
Cease Manufacture
|
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
|
413-110-2
|
135861-56-2
|
2018
|
View substance registered dossier
|
REACH24H CONSULTING GROUP
|
Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
|
Ireland
|
Cease Manufacture
|
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
|
413-110-2
|
135861-56-2
|
2021
|
View substance registered dossier
|
Janssen Pharmaceutica N.V.
|
Turnhoutseweg 30 2340 Beerse Belgium
|
Belgium
|
Cease Manufacture
|
(1R,12R)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.0^{1,12}.0^{6,17}]heptadeca-6(17),7,9,15-tetraen-14-one
|
428-690-2
|
1668-86-6
|
2019
|
View substance registered dossier
|
Aspen Oss BV
|
Kloosterstraat 6 5349 AB Oss Netherlands
|
Netherlands
|
Cease Manufacture
|
(1R,2S,10R,11S,15S)-2,15-dimethyl-4-(morpholin-4-yl)-13-(pyrrolidin-1-yl)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane-5,14-diol
|
601-595-5
|
119302-20-4
|
2022
|
View substance registered dossier
|
Janssen Pharmaceutica N.V.
|
Turnhoutseweg 30 2340 Beerse Belgium
|
Belgium
|
Cease Manufacture
|
(1R,2S,3S,4R)-3-((2-chloro-5-fluoropyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic acid
|
821-184-6
|
1777721-60-4
|
2022
|
View substance registered dossier
|
Janssen Pharmaceutica N.V.
|
Turnhoutseweg 30 2340 Beerse Belgium
|
Belgium
|
Cease Manufacture
|
(1R,2S,3S,4R)-3-((5-fluoro-2-(5-fluoro-1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic acid
|
821-185-1
|
1777721-63-7
|
2022
|
View substance registered dossier
|
Evonik Operations GmbH
|
Rellinghauser Straße 1-11 45128 Essen Germany
|
Germany
|
Cease Manufacture
|
(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl (2R,5R)-5-hydroxy-1,3-oxathiolane-2-carboxylate
|
604-569-1
|
147126-62-3
|
2021
|
View substance registered dossier
|
HH Compliance Ltd
|
Rubicon Building CIT Campus T12 Y275 Bishopstown Cork Ireland
|
Ireland
|
Cease Manufacture
|
(1R,2S,8S,10S,11S,13R,14R,15S,17S)-1,8-difluoro- 14,17dihydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-14-carbothioic S-acid
|
617-081-9
|
80473-92-3
|
2023
|
View substance registered dossier
|
N.V. Ajinomoto OmniChem S.A.
|
Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium
|
Belgium
|
Cease Manufacture
|
(1R,3R,4S,5R)-methyl 3-acetoxy-4-hydroxy-5-(tosyloxy)cyclohexanecarboxylate
|
813-307-7
|
1104200-22-7
|
2020
|
View substance registered dossier
|
N.V. Ajinomoto OmniChem S.A.
|
Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium
|
Belgium
|
Cease Manufacture
|
(1R,3S,5S)-8-benzyl-8-azabicyclo[3.2.1]octan-3-amine fumarate
|
943-085-8
|
-
|
2021
|
View substance registered dossier
|
Cheminova A/S
|
Thyborønvej 78 DK-7673 Harboøre Denmark
|
Denmark
|
Cease Manufacture
|
(1R,4R,5S)-6,6-dimethyl-4-(tribromomethyl)-3-oxabicyclo[3.1.0]hexan-2-one
|
619-738-5
|
87305-03-1
|
2014
|
View substance registered dossier
|
[Confidential]
|
-
|
-
|
-
|
(1R,4S,4aS,8aR)-9-(dichloromethylene)-1,4,4a,8a-tetrahydro-1,4-methanonaphthalene-5,8-dione
|
807-377-8
|
1263184-85-5
|
-
|
View substance registered dossier
|
Minakem Dunkerque Production
|
224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France
|
France
|
Cease Manufacture
|
(1R,7S)-10,10-Dimethyl-3-thia-4-azatricyclo[5.2.1.0(1,5)]dec-4-ene 3,3-dioxide
|
621-464-6
|
107869-45-4
|
2019
|
View substance registered dossier
|
Bidachem S.p.A.
|
S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy
|
Italy
|
Cease Manufacture
|
(1S)-1-cyclopropylethanamine; (2R)-2-hydroxy-2-phenyl-acetic acid
|
946-290-0
|
2246580-61-8
|
2022
|
View substance registered dossier
|
Boehringer Ingelheim Pharma GmbH & Co. KG
|
Binger Strasse 173 55216 Ingelheim am Rhein Germany
|
Germany
|
Cease Manufacture
|
(1S)-1-cyclopropylethanamine; (2R)-2-hydroxy-2-phenyl-acetic acid
|
946-290-0
|
2246580-61-8
|
2022
|
View substance registered dossier
|
Janssen Pharmaceutica N.V.
|
Turnhoutseweg 30 2340 Beerse Belgium
|
Belgium
|
Cease Manufacture
|
(1S)-2,3,4,6-TETRA-O-ACETYL-1,5-ANHYDRO-1-(3-{[5-(4-FLUOROPHENYL)THIOPHEN-2-YL]METHYL}-4-METHYLPHENYL)-D-GLUCITOL
|
617-901-5
|
866607-35-4
|
2022
|
View substance registered dossier
|
N.V. Ajinomoto OmniChem S.A.
|
Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium
|
Belgium
|
Cease Manufacture
|
(1S)-2,3,4,6-TETRA-O-ACETYL-1,5-ANHYDRO-1-(3-{[5-(4-FLUOROPHENYL)THIOPHEN-2-YL]METHYL}-4-METHYLPHENYL)-D-GLUCITOL
|
617-901-5
|
866607-35-4
|
2019
|
View substance registered dossier
|
N.V. Ajinomoto OmniChem S.A.
|
Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium
|
Belgium
|
Cease Manufacture
|
(1S,2R)-1-((2R,3R,4S,6S)-3-acetamido-4-(diallylamino)-6-hydroxy-6-(methoxycarbonyl)tetrahydro-2H-pyran-2-yl)propane-1,2,3-triyl triacetate
|
700-779-3
|
-
|
2020
|
View substance registered dossier
|
N.V. Ajinomoto OmniChem S.A.
|
Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium
|
Belgium
|
Cease Manufacture
|
(1S,3R,4R,5R)-methyl 3-acetoxy-4,5-dihydroxycyclohexanecarboxylate
|
839-204-7
|
1104200-21-6
|
2020
|
View substance registered dossier
|
N.V. Ajinomoto OmniChem S.A.
|
Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium
|
Belgium
|
Cease Manufacture
|
(1S,3R,4R,5S)-methyl 3-acetoxy-5-azido-4-(((2S,3S,4R,5R,6S)-3,4,5-tris(benzyloxy)-6-methyltetrahydro-2H-pyran-2-yl)oxy)cyclohexanecarboxylate
|
813-345-4
|
1104200-23-8
|
2020
|
View substance registered dossier
|
Productos Esteve Internacional, S.A
|
Avd. Verge Montserrat, 12. 08024 Barcelona Barcelona Spain
|
Spain
|
Cease Manufacture
|
(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol hydrochloride
|
700-391-4
|
6953-28-2
|
2017
|
View substance registered dossier
|
Stewardship Chemicals 40
|
Długosza 67 43-188 Orzesze Poland
|
Poland
|
Cease Manufacture
|
(2,4-Difluorophenyl)(4-Fluorophenyl)methanone
|
813-638-7
|
80512-44-3
|
2023
|
View substance registered dossier
|
WeylChem Lamotte S.A.S
|
Rue du Flottage B.P. 1 60350 Trosly Breuil France
|
France
|
Cease Manufacture
|
(2,5-dimethylphenyl)-acetyl chloride
|
470-780-9
|
-
|
2019
|
View substance registered dossier
|
BASF SE
|
Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
|
Germany
|
Cease Manufacture
|
(2-hydroxyethyl)(3-hydroxypropyl)dimethylammonium chloride
|
278-860-3
|
78182-00-0
|
2020
|
View substance registered dossier
|
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik
|
Kalkstrasse 218 51377 Leverkusen Germany
|
Germany
|
Cease Manufacture
|
(2R)-2-(2,4-difluorophenyl)-1,1-difluoro-1-{5-[4-(2,2,2-trifluoroethoxy)phenyl]pyridin-2-yl}-3-(1H-tetrazol-1-yl)propan-2-ol
|
841-499-2
|
1340593-59-0
|
2022
|
View substance registered dossier
|
[Confidential]
|
-
|
-
|
-
|
(2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-(benzoyloxymethyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate
|
807-677-9
|
817204-32-3
|
-
|
View substance registered dossier
|
N.V. Ajinomoto OmniChem S.A.
|
Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium
|
Belgium
|
Cease Manufacture
|
(2R,3R,4S,5R)-2-(acetoxymethyl)-6-oxotetrahydro-2H-pyran-3,4,5-triyl triacetate
|
612-107-5
|
61259-48-1
|
2019
|
View substance registered dossier
|
DSM Nutritional Products GmbH
|
Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany
|
Germany
|
Cease Manufacture
|
(2S)-1,1-diphenylpropane-1,2-diol
|
443-220-6
|
46755-94-6
|
2019
|
View substance registered dossier
|
TAMARANG, S.A.
|
Balmes, 84, 4-2 08008 Barcelona Barcelona Spain
|
Spain
|
Cease Manufacture
|
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
|
406-310-6
|
-
|
2012
|
View substance registered dossier
|
MITSUBISHI GAS CHEMICAL EUROPE GMBH
|
Immermannstr.13 40210 Duesseldorf Germany
|
Germany
|
Cease Manufacture
|
(2S)-2-Aminobutyramide Hydrochloride
|
471-490-5
|
7682-20-4
|
2013
|
View substance registered dossier
|
OLON Spa
|
Strada Rivoltana Km 6/7 20053 RODANO Milano Italy
|
Italy
|
Cease Manufacture
|
(2S)-2-{[(1E)-(5-chloro-2-hydroxyphenyl)(phenyl)methylene]amino}-3-methylbutanoic acid
|
609-516-6
|
38075-43-3
|
2022
|
View substance registered dossier
|
Avara Shannon Pharmaceutical Services Limited
|
Shannon Industrial Estate V14 FX09 Shannon Clare Ireland
|
Ireland
|
Cease Manufacture
|
(2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride (1:1)
|
695-797-0
|
93601-86-6
|
2021
|
View substance registered dossier
|
Avara Shannon Pharmaceutical Services Limited
|
Shannon Industrial Estate V14 FX09 Shannon Clare Ireland
|
Ireland
|
Cease Manufacture
|
(2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-aminium (2R)-(2-chlorophenyl)(hydroxy)acetate
|
814-350-4
|
1352917-66-8
|
2021
|
View substance registered dossier
|
Janssen Pharmaceutica N.V.
|
Turnhoutseweg 30 2340 Beerse Belgium
|
Belgium
|
Cease Manufacture
|
(2S)-{[(benzyloxy)carbonyl]amino}(cyclohexyl)acetic acid
|
478-210-0
|
69901-75-3
|
2019
|
View substance registered dossier
|
N.V. Ajinomoto OmniChem S.A.
|
Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium
|
Belgium
|
Cease Manufacture
|
(2S,3R,4R,5S,6R)-3,4,5-tris(benzyloxy)-2-methyl-6-(p-tolylthio)tetrahydro-2H-pyran
|
835-228-7
|
211801-54-6
|
2021
|
View substance registered dossier
|
N.V. Ajinomoto OmniChem S.A.
|
Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium
|
Belgium
|
Cease Manufacture
|
(2S,3R,4S,5R,6R)-6-(acetoxymethyl)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-2-hydroxytetrahydro-2H-pyran-3,4,5-triyl triacetate
|
921-285-6
|
1071929-02-6
|
2019
|
View substance registered dossier
|
Warsaw University of Technology, Faculty of Chemistry, Laboratory of Technological Processes
|
Noakowskiego 3 00-664 Warszawa Poland
|
Poland
|
Cease Manufacture
|
(2S,3S)-2,3-Bis((4-methoxybenzoyl)oxy)succinic acid
|
606-247-6
|
191605-10-4
|
2014
|
View substance registered dossier
|
Janssen Pharmaceutica N.V.
|
Turnhoutseweg 30 2340 Beerse Belgium
|
Belgium
|
Cease Manufacture
|
(2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride
|
478-270-8
|
-
|
2019
|
View substance registered dossier
|
F.I.S. Fabbrica Italiana Sintetici S.p.a.
|
Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy
|
Italy
|
Cease Manufacture
|
(2S,3S,5R)-2-hexyl-3-hydroxy-5-(phenylmethoxy)-Hexadecanoic acid compd. with (S)-α-methylbenzenemethanamine (1:1)
|
604-018-5
|
137433-01-3
|
2015
|
View substance registered dossier
|
Patheon Austria GmbH & Co KG
|
St. Peter Strasse 25 4020 Linz Austria
|
Austria
|
Cease Manufacture
|
(2S,3S,5R)-2-hexyl-3-hydroxy-5-(phenylmethoxy)-Hexadecanoic acid compd. with (S)-α-methylbenzenemethanamine (1:1)
|
604-018-5
|
137433-01-3
|
2020
|
View substance registered dossier
|
Global Product Compliance (Europe) AB
|
IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden
|
Sweden
|
Cease Manufacture
|
(2α,4aα,8β)-hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalen-8(5H)-one
|
249-648-8
|
29461-13-0
|
2020
|
View substance registered dossier
|
Aspen Oss BV
|
Kloosterstraat 6 5349 AB Oss Netherlands
|
Netherlands
|
Cease Manufacture
|
(3 β, 5 α, 6β)-3-(acetyloxy)-5-bromo-6-hydroxy-androstan-17-one
|
419-790-7
|
4229-69-0
|
2019
|
View substance registered dossier
|
Saltigo GmbH
|
HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany
|
Germany
|
Cease Manufacture
|
(3,4-Dimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-yl)-methylamine
|
917-818-7
|
73344-75-9
|
2013
|
View substance registered dossier
|
Boehringer Ingelheim Pharma GmbH & Co. KG
|
Binger Strasse 173 55216 Ingelheim am Rhein Germany
|
Germany
|
Cease Manufacture
|
(3-aminophenyl)pyridin-3-ylmethanone
|
428-230-0
|
79568-06-2
|
2015
|
View substance registered dossier
|
Global Product Compliance (Europe) AB
|
IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden
|
Sweden
|
Cease Manufacture
|
(3-aminophenyl)urea
|
247-201-1
|
25711-72-2
|
2022
|
View substance registered dossier
|
Global Product Compliance (Europe) AB
|
IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden
|
Sweden
|
Cease Manufacture
|
(3-aminophenyl)uronium chloride
|
261-858-1
|
59690-88-9
|
2022
|
View substance registered dossier
|
N.V. Ajinomoto OmniChem S.A.
|
Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium
|
Belgium
|
Cease Manufacture
|
(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl methanesulfonate
|
700-367-3
|
35130-97-3
|
2012
|
View substance registered dossier
|
N.V. Ajinomoto OmniChem S.A.
|
Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium
|
Belgium
|
Cease Manufacture
|
(3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl[(methylsulfonyl)oxy]acetate
|
700-396-1
|
60924-38-1
|
2012
|
View substance registered dossier
|
Janssen Pharmaceutica N.V.
|
Turnhoutseweg 30 2340 Beerse Belgium
|
Belgium
|
Cease Manufacture
|
(3beta)-17-(3-pyridinyl)androsta-5,16-dien-3-yl acetate compound with (2R,3R)-tartaric acid and methanol (1 : 1 : 1.5)
|
931-336-4
|
-
|
2019
|
View substance registered dossier
|
Agfa-Gevaert N.V.
|
Septestraat 27 2640 Mortsel Belgium
|
Belgium
|
Cease Manufacture
|
(3E)-2-chloro-3-(hydroxymethylene)cyclohexene-1-carbaldehyde
|
801-656-8
|
1416808-92-8
|
2021
|
View substance registered dossier
|
Esteve Quimica, S.A.
|
Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain
|
Spain
|
Cease Manufacture
|
(3R)-3-(2-amino-2-oxoethyl)-5-methylhexanoic acid
|
605-923-8
|
181289-33-8
|
2017
|
View substance registered dossier
|
[Confidential]
|
-
|
-
|
-
|
(3R,4R,5R,6R,9R,10Z,11R,12S,14S)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione 10-oxime
|
603-883-6
|
134931-01-4
|
-
|
View substance registered dossier
|
Hovione FarmaCiencia SA
|
Sete Casas 2674-506 Loures Portugal
|
Portugal
|
Cease Manufacture
|
(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-10-hydroxyimino-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one
|
603-467-4
|
13127-18-9
|
2017
|
View substance registered dossier
|
MINAKEM Beuvry Production SAS
|
145, Chemin des Lilas 59310 Beuvry-la-Forêt France
|
France
|
Cease Manufacture
|
(3R,7aR)-3-tert-butyl-1,5-dioxodihydro-1H-pyrrolo[1,2-c][1,3]oxazole-7a(5H)-carbaldehyde
|
812-036-1
|
1214741-19-1
|
2019
|
View substance registered dossier
|
MINAKEM Beuvry Production SAS
|
145, Chemin des Lilas 59310 Beuvry-la-Forêt France
|
France
|
Cease Manufacture
|
(3R,7aR)-3-tert-butyl-7a-{methoxy[(trimethylsilyl)oxy]methyl}dihydro-1H-pyrrolo[1,2-c][1,3]oxazole-1,5(6H)-dione
|
942-823-6
|
-
|
2019
|
View substance registered dossier
|
MINAKEM Beuvry Production SAS
|
145, Chemin des Lilas 59310 Beuvry-la-Forêt France
|
France
|
Cease Manufacture
|
(3R,7aS)-3-tert-butyldihydro-1H-pyrrolo[1,2-c]oxazole-1,5(6H)-dione
|
810-392-2
|
171284-84-7
|
2019
|
View substance registered dossier
|
Roche Ireland Limited
|
Clarehill . Clarecastle Ireland
|
Ireland
|
Cease Manufacture
|
(3S,4aS,8aS)-2-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-tert-butyldecahydroisoquinoline-3-carboxamide
|
430-230-0
|
136522-17-3
|
2020
|
View substance registered dossier
|
Roche Ireland Limited
|
Clarehill . Clarecastle Ireland
|
Ireland
|
Cease Manufacture
|
(3S,4aS,8aS)-N-tert-Butyldecahydro-3-isoquinolinecarboxamide
|
420-380-5
|
136465-81-1
|
2020
|
View substance registered dossier
|
CU Chemie Uetikon GmbH
|
Raiffeisenstrasse 4 77933 Lahr Germany
|
Germany
|
Cease Manufacture
|
(3S,5R,8aS)-3-phenyl-3,5,6,7,8,8a-hexahydro-2H-oxazolo[3,2-a]pyridine-5-carbonitrile
|
634-598-5
|
106565-71-3
|
2020
|
View substance registered dossier
|
Lek Pharmaceuticals d.d.
|
Verovskova 57 1526 Ljubljana Slovenia
|
Slovenia
|
Cease Manufacture
|
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]-oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
|
610-965-5
|
53123-88-9
|
2017
|
View substance registered dossier
|
Santrol Europe ApS
|
Aagade 103 Pjedsted 7000 Fredericia Denmark
|
Denmark
|
Cease Manufacture
|
(3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione
|
224-832-0
|
4511-42-6
|
2016
|
View substance registered dossier
|
Global Product Compliance (Europe) AB
|
IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden
|
Sweden
|
Cease Manufacture
|
(4-(4-aminophenyl)(4-iminocyclohexa-2,5-dienylidene)methyl)-2-methylaniline hydrochloride
|
211-189-6
|
632-99-5
|
2023
|
View substance registered dossier
|
Evonik Operations GmbH
|
Rellinghauser Straße 1-11 45128 Essen Germany
|
Germany
|
Cease Manufacture
|
(4-benzylpiperazin-1-yl)(cyclopropyl)methanone hydrochloride
|
816-907-7
|
1294454-93-5
|
2021
|
View substance registered dossier
|
Derivados Quimicos SAU
|
Strada Rivoltana km6/7 20053 Rodano (Milano) Lombardia Spain
|
Spain
|
Cease Manufacture
|
(4-Chloro-2-fluoro-phenyl)-acetonitrile
|
642-783-7
|
75279-53-7
|
2020
|
View substance registered dossier
|
Bidachem S.p.A.
|
S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy
|
Italy
|
Cease Manufacture
|
(4-cyclopropyl-6-methyl-pyrimidin-5-yl)boronic acid
|
826-639-2
|
1817776-86-5
|
2022
|
View substance registered dossier
|
Boehringer Ingelheim Pharma GmbH & Co. KG
|
Binger Strasse 173 55216 Ingelheim am Rhein Germany
|
Germany
|
Cease Manufacture
|
(4-cyclopropyl-6-methyl-pyrimidin-5-yl)boronic acid
|
826-639-2
|
1817776-86-5
|
2022
|
View substance registered dossier
|
INTEROR
|
49, rue d'Ostende F-62100 CALAIS France
|
France
|
Cease Manufacture
|
(4-ethoxyphenyl)(3-(4-fluoro-3-phenoxyphenyl)propyl)dimethylsilane
|
405-020-7
|
105024-66-6
|
2022
|
View substance registered dossier
|
Bayer AG
|
Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany
|
Germany
|
Cease Manufacture
|
(4-ethoxyphenyl)(3-(4-fluoro-3-phenoxyphenyl)propyl)dimethylsilane
|
405-020-7
|
105024-66-6
|
2010
|
View substance registered dossier
|
-
|
-
|
-
|
-
|
(4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one
|
433-160-9
|
-
|
-
|
View substance registered dossier
|
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority.
|
-
|
-
|
No longer Valid
|
(4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid
|
442-870-8
|
-
|
2022
|
View substance registered dossier
|
-
|
-
|
-
|
-
|
(4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid
|
442-870-8
|
-
|
-
|
View substance registered dossier
|
ESIM Chemicals GmbH
|
St.-Peter-Strasse 25 4020 Linz Austria
|
Austria
|
Cease Manufacture
|
(4Z)-3-methyl-N-nitro-5-{[2-(phenylsulfanyl)-1,3-thiazol-5-yl]methyl}-1,3,5-oxadiazinan-4-imine
|
427-600-9
|
192439-46-6
|
2022
|
View substance registered dossier
|
Novartis Ringaskiddy Limited
|
. . Ringaskiddy County Cork Ireland
|
Ireland
|
Cease Manufacture
|
(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid
|
700-141-4
|
117570-53-3
|
2015
|
View substance registered dossier
|
Aspen Oss BV
|
Kloosterstraat 6 5349 AB Oss Netherlands
|
Netherlands
|
Cease Manufacture
|
(5α)-Androsta-2,16-dien-17-yl acetate
|
610-545-1
|
50588-42-6
|
2019
|
View substance registered dossier
|
HH Compliance Ltd
|
Rubicon Building CIT Campus T12 Y275 Bishopstown Cork Ireland
|
Ireland
|
Cease Manufacture
|
(6ALPHA,11BETA,16ALPHA,17ALPHA)-6,9-DIFLUORO-11-HYDRO XY-16-METHYL-3-OXO-17- (1-OXOPROPOXY)ANDROSTA-1,4-DIENE-CARBOTHIOIC ACID
|
617-084-5
|
80474-45-9
|
2023
|
View substance registered dossier
|
Corden Pharma Latina S.p.A.
|
Via Murillo, 7 IT04013 Sermoneta (LT) Lazio Italy
|
Italy
|
Cease Manufacture
|
(6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3)
|
939-998-6
|
-
|
2017
|
View substance registered dossier
|
Sandoz GmbH
|
Biochemiestr. 10 6250 Kundl Austria
|
Austria
|
Cease Manufacture
|
(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylic acid, 1-butylammonium salt
|
439-350-8
|
-
|
2021
|
View substance registered dossier
|
Sandoz GmbH
|
Biochemiestr. 10 6250 Kundl Austria
|
Austria
|
Cease Manufacture
|
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrochloride
|
600-507-2
|
103980-44-5
|
2021
|
View substance registered dossier
|
Sandoz GmbH
|
Biochemiestr. 10 6250 Kundl Austria
|
Austria
|
Cease Manufacture
|
(6R,7R)-7-amino-3-(5H-imidazo[1,2-b]pyridazin-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydroiodide
|
606-382-0
|
197897-11-3
|
2021
|
View substance registered dossier
|
Sandoz GmbH
|
Biochemiestr. 10 6250 Kundl Austria
|
Austria
|
Cease Manufacture
|
(6R,7R)-7-amino-3-{[(furan-2-ylcarbonyl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
|
617-065-1
|
80370-59-8
|
2021
|
View substance registered dossier
|
Sandoz GmbH
|
Biochemiestr. 10 6250 Kundl Austria
|
Austria
|
Cease Manufacture
|
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
|
700-301-3
|
69739-16-8
|
2021
|
View substance registered dossier
|
Sandoz GmbH
|
Biochemiestr. 10 6250 Kundl Austria
|
Austria
|
Cease Manufacture
|
(6R-trans)-1-((7-Ammonio-2-carboxylato-8-oxo-5-thia-1-azabicyclo-(4.2.0)oct-2-en-3-yl)methyl)pyridinium iodide
|
423-260-0
|
100988-63-4
|
2021
|
View substance registered dossier
|
Sandoz GmbH
|
Biochemiestr. 10 6250 Kundl Austria
|
Austria
|
Cease Manufacture
|
(6R-trans)-7-amino-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
|
619-847-8
|
111298-82-9
|
2021
|
View substance registered dossier
|
Sandoz GmbH
|
Biochemiestr. 10 6250 Kundl Austria
|
Austria
|
Cease Manufacture
|
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
|
261-491-7
|
58909-56-1
|
2020
|
View substance registered dossier
|
Sandoz GmbH
|
Biochemiestr. 10 6250 Kundl Austria
|
Austria
|
Cease Manufacture
|
(6S,7S)-7-Amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
|
435-680-1
|
-
|
2021
|
View substance registered dossier
|
[Confidential]
|
-
|
-
|
-
|
(6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid
|
434-320-0
|
-
|
-
|
View substance registered dossier
|
HH Compliance Ltd
|
Rubicon Building CIT Campus T12 Y275 Bishopstown Cork Ireland
|
Ireland
|
Cease Manufacture
|
(6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid
|
434-320-0
|
-
|
2023
|
View substance registered dossier
|
Centrient Pharmaceuticals Netherlands B.V.
|
Alexander Fleminglaan 1 2613 AX Delft Netherlands
|
Netherlands
|
Cease Manufacture
|
(7R)-7-(4-carboxybutanamido)cephalosporanate amidohydrolase (enzyme substance)
|
611-406-8
|
56645-46-6
|
2022
|
View substance registered dossier
|
Aspen Oss BV
|
Kloosterstraat 6 5349 AB Oss Netherlands
|
Netherlands
|
Cease Manufacture
|
(8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,8,9,10,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
|
608-630-3
|
31528-46-8
|
2022
|
View substance registered dossier
|
Archroma Italy, S.r.l. - OR
|
Via Manzoni 37 20030 Palazzolo Milanese Italy
|
Italy
|
Cease Manufacture
|
(Benzyloxycarbonyl)methyl 3-[5-acetamido-4-(2-chloro-4,6-dinitrophenylazo)-2-methoxyanilino]propionate
|
436-000-6
|
159010-67-0
|
2017
|
View substance registered dossier
|
|
|
|
|
|
|
|
|
|