Registered substances
Registered substances
In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).
ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.
As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).
In the portal results table are presented:
- Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
- Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
- Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
- Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
- Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
- Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
- Link to the full factsheet.
A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.
- The REACH Registered substance portal was updated on 9th November 2020; the REACH registered factsheets were further updated on 21st December 2020. Details of the improvements can be found at Dissemination Platform Updates. Reprocessing the entire dataset is ongoing since 21 December 2020. ECHA is making all possible efforts to make the improvements and additional data visible with the shortest delay.
- The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
Further information
- Registered substances information
- How to determine what will be published (Data Submission Manual 15)
- Understanding REACH Regulation
- Q&A on registered substances
- What is an Infocard? [PDF]
- What is a Registered substance Factsheet? [PDF]
- eChemPortal
- REACH study results download
- REACH Regulation
- ECHA Legal notice
Last updated 01 March 2021. Database contains 23117 unique substances and contains information from 93430 dossiers.
Registrant/Supplier | Address | Country | Registration Status | Name | EC / List no. | CAS no. | Last update year | Details |
---|---|---|---|---|---|---|---|---|
- | - | - | - | 4-benzyl-2,6-dihydroxy-4-aza-heptylene bis(2,2-dimethyloctanoate) | 418-100-1 | 172964-15-7 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 4-benzyloxy-4'-(2,3-epoxy-2-methylprop-1-yloxy)diphenylsulfone | 408-220-2 | 141420-50-0 | - | View substance registered dossier |
Honeywell Specialty Chemicals Seelze GmbH | Wunstorfer Strasse 40 D-30926 Seelze Lower Saxony Germany | - | - | 4-bromo-2-chlorofluorobenzene | 405-580-2 | 60811-21-4 | - | View substance registered dossier |
Bayer AG | Kaiser-Wilhelm-Allee 51373 Leverkusen Germany | - | - | 4-bromo-2-chlorofluorobenzene | 405-580-2 | 60811-21-4 | - | View substance registered dossier |
Merck KGaA | Frankfurter Strasse 250 64293 Darmstadt Germany | Germany | Cease Manufacture | 4-bromo-2-fluoro-1-trifluoromethoxybenzene | 430-850-1 | 105529-58-6 | 2019 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. | - | - | Active | 4-chloro-3',4'-dimethoxybenzophenone | 404-610-1 | 116412-83-0 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. | - | - | Active | 4-chloro-3',4'-dimethoxybenzophenone | 404-610-1 | 116412-83-0 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Swedish competent national authority. | - | - | Active | 4-chloro-5-methylbenzotriazole sodium salt; 5-chloro-4-methylbenzotriazole sodium salt; reaction mass of: 4-chloro-7-methylbenzotriazole sodium salt | 427-730-6 | 202420-04-0 | - | View substance registered dossier |
SUEZ WATER TECHNOLOGIES & SOLUTIONS (UK) LIMITED PARTNERSHIP | HydroHouse - Newcombe Way Orton Southgate PE2 6SE Peterborough Cambridgeshire United Kingdom | United Kingdom | No longer Valid | 4-chloro-5-methylbenzotriazole sodium salt; 5-chloro-4-methylbenzotriazole sodium salt; reaction mass of: 4-chloro-7-methylbenzotriazole sodium salt | 427-730-6 | 202420-04-0 | 2021 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 4-chloro-5-methylbenzotriazole sodium salt; 5-chloro-4-methylbenzotriazole sodium salt; reaction mass of: 4-chloro-7-methylbenzotriazole sodium salt | 427-730-6 | 202420-04-0 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 4-chlorophenyl cyclopropyl ketone O-(4-aminobenzyl)oxime | 405-260-2 | 94050-51-8 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 4-CPH | 428-130-7 | - | - | View substance registered dossier |
- | - | - | - | 4-Cyano-4'-hydroxybiphenyl | 427-840-4 | 19812-93-2 | - | View substance registered dossier |
FIRMENICH GRASSE SAS OR 1 | Parc Industriel Les Bois de Grasse 06130 Grasse France | France | Active | 4-cyclohexyl-2-methyl-2-butanol | 420-630-3 | 83926-73-2 | 2011 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 4-cyclohexyl-2-methyl-2-butanol | 420-630-3 | 83926-73-2 | - | View substance registered dossier |
International Flavors & Fragrances I.F.F. (Nederland) B.V. | Liebergerweg 72-98 1221 JT Hilversum Netherlands | Netherlands | Active | 4-cyclohexyl-2-methyl-2-butanol | 420-630-3 | 83926-73-2 | - | View substance registered dossier |
PCAS | 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France | France | Active | 4-decyl-1,3-oxazolidin-2-one; 4-decyloxazolidin-2-one | 443-770-7 | 7693-82-5 | - | View substance registered dossier |
Central Glass Germany GmbH | Kantstrasse 2 33790 Halle/Westf. Nordrhein Westfalen Germany | Germany | Active | 4-decyl-1,3-oxazolidin-2-one; 4-decyloxazolidin-2-one | 443-770-7 | 7693-82-5 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. | - | - | Active | 4-dichloroacetyl-1-oxa-4-azaspiro[4.5]decane | 401-130-4 | 71526-07-3 | - | View substance registered dossier |
Merck Performance Materials GmbH | Rheingaustrasse 190-196 65203 Wiesbaden Germany | Germany | Cease Manufacture | 4-dimethylaminobenzenediazonium 3-carboxy-4-hydroxybenzenesulfonate | 404-980-4 | 124737-31-1 | 2019 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 4-ethyl-1,3-dioxolan-2-one | 403-780-4 | - | - | View substance registered dossier |
Huntsman (Europe) BV - OR1 | Everslaan 45 B-3078 Everberg Belgium | Belgium | Active | 4-ethyl-1,3-dioxolan-2-one | 403-780-4 | - | 2011 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | 4-ethyl-2-fluoro-4'-(2-(trans-4-pentylcyclohexyl)ethyl)biphenyl | 433-390-1 | 95379-18-3 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | 4-ethyl-2-fluoro-4'-(2-(trans-4-propylcyclohexyl)ethyl)biphenyl | 433-190-2 | - | - | View substance registered dossier |
ANGUS CHEMIE GMBH | Zeppelinstr. 30 Postfach 4003 D-49479 Ibbenbueren-Uffeln Germany | Germany | Active | 4-ethyl-2-methyl-2-isopentyl-1,3-oxazolidine | 410-470-2 | 137796-06-6 | 2011; 2012 | View substance registered dossier |
- | - | - | - | 4-Fluoro-3-hydroxybenzoic acid | 434-190-5 | - | - | View substance registered dossier |
FujiFilm Manufacturing Europe BV | Oudenstaart 1 5047 TK Tilburg Netherlands | Netherlands | Active | 4-hexadecyl-1-phenylpyrazolidin-3-one | 430-840-7 | - | 2011 | View substance registered dossier |
Honeywell Specialty Chemicals Seelze GmbH | Wunstorfer Strasse 40 D-30926 Seelze Lower Saxony Germany | Germany | Cease Manufacture | 4-hexadecyl-1-phenylpyrazolidin-3-one | 430-840-7 | - | 2020 | View substance registered dossier |
- | - | - | - | 4-hexenal , 6-(2,2,3-trimethyl-3-cyclopenten-1-yl)- | 484-020-9 | 1016902-02-5 | - | View substance registered dossier |
Janssen Pharmaceutica N.V. | Turnhoutseweg 30 2340 Beerse Belgium | Belgium | Cease Manufacture | 4-Hydroxy-3,5-dimethylbenzonitrile | 452-810-2 | - | 2019 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 4-hydroxy-7-(2-aminoethyl)-1,3-benzothiazol-2(3H)-one hydrochloride | 432-470-1 | 189012-93-9 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | 4-hydroxyphenyl 4-(allyloxy)benzoate | 433-210-1 | - | - | View substance registered dossier |
- | - | - | - | 4-hydroxyphenyl 4-(allyloxy)benzoate | 433-210-1 | - | - | View substance registered dossier |
- | - | - | - | 4-hydroxyphenyl-alpha-D-glucopyranoside | 440-470-8 | 84380-01-8 | - | View substance registered dossier |
MITSUBISHI GAS CHEMICAL EUROPE GMBH | Immermannstr. 13 40210 Duesseldorf Germany | Germany | Active | 4-Isobutylbenzaldehyde | 464-400-0 | - | 2014 | View substance registered dossier |
MITSUBISHI GAS CHEMICAL EUROPE GMBH | Immermannstr.13 40210 Duesseldorf Germany | Germany | Active | 4-Isobutylbenzaldehyde | 464-400-0 | - | 2014 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Swedish competent national authority. | - | - | Active | 4-mesyl-2-nitrotoluene | 430-550-0 | 1671-49-4 | - | View substance registered dossier |
Clariant Produkte (Deutschland) GmbH | Am Unisys-Park 1 65843 Sulzbach am Taunus Germany | Germany | Cease Manufacture | 4-mesyl-2-nitrotoluene | 430-550-0 | 1671-49-4 | 2013 | View substance registered dossier |
AllessaProduktion GmbH | Alt-Fechenheim 34 60386 Frankfurt am Main Germany | Germany | Cease Manufacture | 4-mesyl-2-nitrotoluene | 430-550-0 | 1671-49-4 | 2013 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. | - | - | Active | 4-mesyl-2-nitrotoluene | 430-550-0 | 1671-49-4 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 4-mesyl-2-nitrotoluene | 430-550-0 | 1671-49-4 | - | View substance registered dossier |
AlzChem Trostberg GmbH | Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany | - | - | 4-methoxy-N,6-dimethyl-1,3,5-triazin-2-ylamine | 401-360-5 | 5248-39-5 | - | View substance registered dossier |
- | - | - | - | 4-methoxy-N,6-dimethyl-1,3,5-triazin-2-ylamine | 401-360-5 | 5248-39-5 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority. | - | - | Active | 4-methoxybenzyl 3-chloromethyl-5-oxo-6-phenylacetamido-(2H)5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate | 403-040-0 | - | - | View substance registered dossier |
Bristol Myers Squibb Srl | Via del Murillo., km 2, 8 004013 Sermoneta Lazio Italy | Italy | Active | 4-methoxybenzyl 3-chloromethyl-5-oxo-6-phenylacetamido-(2H)5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate | 403-040-0 | - | - | View substance registered dossier |
Merck KGaA | Frankfurter Strasse 250 64293 Darmstadt Germany | Germany | Cease Manufacture | 4-Methyl-2-propylbenzimidazole-6-carboxylic acid | 424-450-6 | - | 2019 | View substance registered dossier |
ORGAPHARM | Rue du Moulin de la Canne 45300 PITHIVIERS France | France | Active | 4-Methyl-2-propylbenzimidazole-6-carboxylic acid | 424-450-6 | - | - | View substance registered dossier |
Boehringer Ingelheim Pharma GmbH & Co. KG | Binger Strasse 173 55216 Ingelheim am Rhein Germany | Germany | Cease Manufacture | 4-Methyl-2-propylbenzimidazole-6-carboxylic acid | 424-450-6 | - | 2015 | View substance registered dossier |
Pfizer Ireland Pharmaceuticals | n/a P43 X3336 Ringaskiddy Cork Ireland | Ireland | No longer Valid | 4-methyl-3-oxo-N-phenyl-2-(phenylmethylene)pentanamide | 425-860-8 | 125971-57-5 | 2013 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | 4-methyl-3-oxo-N-phenyl-2-(phenylmethylene)pentanamide | 425-860-8 | 125971-57-5 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. | - | - | Active | 4-methyl-3-oxo-N-phenyl-2-(phenylmethylene)pentanamide | 425-860-8 | 125971-57-5 | - | View substance registered dossier |
Pfizer Ireland Pharmaceuticals | n/a P43 X3336 Ringaskiddy Cork Ireland | Ireland | Cease Manufacture | 4-methyl-3-oxo-N-phenyl-2-(phenylmethylene)pentanamide | 425-860-8 | 125971-57-5 | 2019 | View substance registered dossier |
- | - | - | - | 4-methyl-8-methylenetricyclo[3.3.1.13,7]dec-2-yl acetate | 406-560-6 | 122760-85-4 | - | View substance registered dossier |
International Flavors & Fragrances I.F.F. (Nederland) B.V. | Liebergerweg 72-98 1221 JT Hilversum Netherlands | Netherlands | Active | 4-methyl-8-methylenetricyclo[3.3.1.13,7]dec-2-yl acetate | 406-560-6 | 122760-85-4 | - | View substance registered dossier |
IFF Benicarlo, S.L. | Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain | - | - | 4-methyl-8-methylenetricyclo[3.3.1.13,7]decan-2-ol | 406-330-5 | 122760-84-3 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | 4-methyl-N,N-bis(2-(((4-methylphenyl)sulfonyl)amino)ethyl)benzenesulfonamide | 413-300-5 | 56187-04-3 | - | View substance registered dossier |
- | - | - | - | 4-Methyl-N-(3-triethoxysilylpropyl)pentan-2-imine | 467-100-8 | - | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. | - | - | Active | 4-Methyl-N-(3-triethoxysilylpropyl)pentan-2-imine | 467-100-8 | - | - | View substance registered dossier |
Cytec Industries BV | Burgemeester van Lierplein 75 3134 ZB Vlaardingen Netherlands | Netherlands | Active | 4-methyl-N-(methylsulfonyl)benzenesulfonamide | 415-040-8 | 14653-91-9 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. | - | - | Active | 4-methyl-N-phenyl-6-(prop-1-yn-1-yl)pyrimidin-2-amine | 432-140-7 | 110235-47-7 | - | View substance registered dossier |
- | - | - | - | 4-methylphenyl 4-methoxybenzoate | 439-300-5 | - | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. | - | - | Active | 4-MORPHOLINO-2-NAPHTHOL | 435-700-9 | - | - | View substance registered dossier |
Amri Italy S.r.l. | VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy | Italy | Active | 4-nitrophenyl 1,3-thiazol-5-ylmethylcarbonate hydrochloride | 414-490-2 | - | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 4-nitrophenyl 1,3-thiazol-5-ylmethylcarbonate hydrochloride | 414-490-2 | - | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 4-oxo-4-(p-tolyl)butyric acid adduct with 4-ethylmorpholine | 419-240-6 | 171054-89-0 | - | View substance registered dossier |
BASF plc | Earl Road, P O Box 4 SK8 6QG Cheadle Hulme Cheshire United Kingdom | United Kingdom | Cease Manufacture | 4-oxo-4-(p-tolyl)butyric acid adduct with 4-ethylmorpholine | 419-240-6 | 171054-89-0 | 2018 | View substance registered dossier |
Boehringer Ingelheim Pharma GmbH & Co. KG | Binger Strasse 173 55216 Ingelheim am Rhein Germany | Germany | Cease Manufacture | 4-Oxo-butyramide | 464-950-1 | - | 2015 | View substance registered dossier |
Corden Pharma Latina S.p.A. | Via del Murillo Km 2, 800 IT04013 Sermoneta (LT) Lazio Italy | Italy | Cease Manufacture | 4-phenylbut-1-ene | 405-980-7 | 768-56-9 | 2017 | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 4-phenylbut-1-ene | 405-980-7 | 768-56-9 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. | - | - | Active | 4-phenylbut-1-ene | 405-980-7 | 768-56-9 | - | View substance registered dossier |
- | - | - | - | 4-Piperidinone, 2,6-diethyl-2,3,6-trimethyl-1-(1-phenylethoxy)- | 440-550-2 | 244021-01-0 | - | View substance registered dossier |
Mitsubishi Chemical Europe GmbH | Willstätter Strasse 30 40549 Düsseldorf Germany | Germany | Cease Manufacture | 4-tert-butylphenol-formaldehyde copolymer | 472-160-3 | 25085-50-1 | 2018 | View substance registered dossier |
Honeywell Specialty Chemicals Seelze GmbH | Wunstorfer Strasse 40 D-30926 Seelze Lower Saxony Germany | Germany | Active | 493 F | 437-020-8 | - | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 4HBAGE | 437-510-1 | - | - | View substance registered dossier |
Boehringer Ingelheim Pharma GmbH & Co. KG | Binger Strasse 173 55216 Ingelheim am Rhein Germany | Germany | Cease Manufacture | 4’-(2-Propyl-4-methyl-6-(1-methylbenzimidazolyl-2-yl)-benzimidazol-1-ylmethyl)biphenyl-2-carbonsäure Hydrochlorid | 485-140-4 | - | 2015 | View substance registered dossier |
The Acta Group EU BVBA (BE1) | Place du Luxembourg 2 1050 Brussels Belgium | Belgium | Active | 5,5'-thiobis(2-mercapto-1,3,4-thiadiazole) | 452-150-5 | - | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. | - | - | Active | 5,5-dimethyl-perhydro-pyrimidin-2-one α-(4-trifluoromethylstyryl)-α-(4-trifluoromethyl)cinnamylidenehydrazone | 405-090-9 | 67485-29-4 | - | View substance registered dossier |
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. | - | - | Active | 5,5-dimethyl-perhydro-pyrimidin-2-one α-(4-trifluoromethylstyryl)-α-(4-trifluoromethyl)cinnamylidenehydrazone | 405-090-9 | 67485-29-4 | - | View substance registered dossier |
- | - | - | - | 5,6,12,13-tetrachloroanthra(2,1,9-def:6,5,10-d'e'f')diisoquinoline-1,3,8,10(2H,9H)-tetrone | 405-100-1 | 115662-06-1 | - | View substance registered dossier |
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