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Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The REACH Registered substance portal was updated on 9th November 2020; the REACH registered factsheets were further updated on 21st December 2020. Details of the improvements can be found at Dissemination Platform Updates. Reprocessing the entire dataset is ongoing since 21 December 2020. ECHA is making all possible efforts to make the improvements and additional data visible with the shortest delay.
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
Last updated 02 March 2021. Database contains 23184 unique substances and contains information from 93505 dossiers.
Substance identity
Administrative data
Submission type:
First published date:
Last update date:
Substance data
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Uses and exposure
Life cycle:
  • Consumer Uses
  • Article service life
  • Widespread uses by professional workers
  • Formulation or re-packing
  • Uses at industrial sites
  • Manufacture
Category:
Details
3-Amino-tricyclo[3,3,1,13,7]decan-1-ol
450-050-6 - null NONS Individual Tonnage Data Confidential 02-04-2020 View substance registered dossier
3-Amino-tricyclo[3,3,1,13,7]decan-1-ol
450-050-6 - null Intermediate Joint Intermediate Use Only 04-05-2020 View substance registered dossier
3-bromo-1-(3-chloropyrid-2-yl)-5-methyl-1H-pyrazole
952-948-8 - null Full Individual 0 - 10 tonnes per annum 03-09-2020 View substance registered dossier
3-C12-14-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide
931-324-9 - Active Full Joint ≥ 1 000 to < 10 000 tonnes 11-12-2018 View substance registered dossier
3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide
939-581-9 - Active Full Joint ≥ 1 000 to < 10 000 tonnes 22-06-2020 View substance registered dossier
3-cyanomethyl-2-(4-methylphenyl)-6-methylimidozo[1,2-a]pyridine
457-480-3 - Active Intermediate Individual Intermediate use only 01-04-2011 View substance registered dossier
3-Cyclohexyl-2-cyclohexylimino-5-(4-diethylamino-2-methoxyphenyl)methylenoxazolidine-4-one
457-890-2 - null Full Individual 0 - 10 tonnes per annum 24-05-2020 View substance registered dossier
3-Cyclohexyl-2-cyclohexylimino-5-(4-diethylamino-2-methoxyphenyl)methylenoxazolidine-4-one
457-890-2 - null NONS Individual Tonnage Data Confidential 25-08-2020 View substance registered dossier
3-Dimethylamino-1-(pyrid-3-yl)-2-propen-1-one
434-770-8 - Active Intermediate Individual Intermediate use only 28-09-2010 View substance registered dossier
3-Dimethylamino-1-(pyrid-3-yl)-2-propen-1-one
434-770-8 - Active Intermediate Individual Intermediate use only 03-08-2009 View substance registered dossier
3-Ethoxy-(E)-2-propenoic acid ethyl ester
443-080-6 - null Intermediate Joint Intermediate Use Only 04-05-2020 View substance registered dossier
3-ethoxy-4,6-difluoro-7-hexyloxy-dibenzothiophene
950-069-4 - Active Full Joint ≥ 0 to < 10 tonnes 30-11-2020 View substance registered dossier
3-ethyl-1-methyl-1H-imidazol-3-ium 4-(C11-13-sec-alkyl benzenesulfonates)
940-820-4 - Active Full Joint ≥ 0 to < 10 tonnes 18-09-2018 View substance registered dossier
3-ethyl-3-[(2-ethylhexyloxy)methyl]oxetane
445-460-7 - Active NONS Individual Tonnage data confidential 29-10-2012 View substance registered dossier
3-Ethyl-4-methyl-2-oxo-2,5-dihydropyrrole-1-carboxylic acid phenethylamide
925-067-1 - Active Intermediate Joint Intermediate use only 11-04-2018 View substance registered dossier
3-Fluor-4'-propylbiphenyl
923-509-8 - Active Intermediate Joint Intermediate use only 08-12-2017 View substance registered dossier
3-fluoro-4'-(trans-4-propylcyclohexyl)-1,1'-biphenyl
936-120-3 - Active Full Joint ≥ 1 to < 10 tonnes 08-12-2020 View substance registered dossier
3-fluoro-4'-pentyl-1,1'-biphenyl
935-974-4 - Active Intermediate Joint Intermediate use only 24-10-2017 View substance registered dossier
3-hydroxy-3-carbethoxy-1-azabicyclo[2.2.2]octane
925-046-7 - Active Intermediate Joint Intermediate use only 17-10-2017 View substance registered dossier
3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type
931-312-3 - null Full Joint 10 000 - 100 000 tonnes per annum 05-08-2020 View substance registered dossier
3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, uretdione type
938-351-5 - Active Intermediate Joint Intermediate use only 07-02-2017 View substance registered dossier
3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate, oligomers reaction product with 3-(cyclohexylamino)propane-1-sulfonic acid and N,N-dimethylcyclohexanamine
926-601-6 - Active Full Joint ≥ 1 to < 10 tonnes 23-11-2016 View substance registered dossier
3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate, oligomers, 2-Hydroxy-1(2)- methylethyl carbamate blocked
921-910-2 - Active Full Joint ≥ 10 to < 100 tonnes 21-01-2020 View substance registered dossier
3-Mercaptopropyl-functionalized silica gel
945-952-6 - Active Full Joint ≥ 1 to < 10 tonnes 04-07-2018 View substance registered dossier
3-methyl-1,3-butandiol
459-270-7 - Active Full Individual ≥ 10 to < 100 tonnes 03-04-2020 View substance registered dossier
3-methyl-2-oxobutanoic acid, fermentation products
931-029-5 - Cease Manufacture Intermediate Joint Cease manufacture 06-11-2015 View substance registered dossier
3-methyl-3-(2,2,3,3,3-pentafluoropropoxy)methyl oxetane
482-280-8 - Active Full Individual ≥ 1 to < 10 tonnes 24-04-2020 View substance registered dossier
3-methyl-3-(2,2,3,3,3-pentafluoropropoxy)methyl oxetane
482-280-8 - Active NONS Individual Tonnage data confidential 25-06-2009 View substance registered dossier
3-Methyl-4-(4-trifluoromethylsulfanyl-phenoxy)-phenylamine oxalate
929-675-8 - Active Intermediate Joint Intermediate use only 29-10-2018 View substance registered dossier
3-methyl-4-oxo-4-(3-nitro-4-chlorophenyl)butanoic acid
440-860-8 - Active NONS Individual Tonnage data confidential 24-06-2009 View substance registered dossier
3-methyl-4-oxo-4-(3-nitro-4-chlorophenyl)butanoic acid
440-860-8 - Active Intermediate Joint Intermediate use only 15-07-2019 View substance registered dossier
3-methyl-5-phenylmethoxy-2-(4-phenylmethoxyphenyl)-1H-indole
926-072-1 - Active Intermediate Individual Intermediate use only 30-08-2016 View substance registered dossier
3-oxyde-2,4-pyrimidinediamine monohydrate
419-140-2 - Active NONS Joint Tonnage data confidential 26-10-2012 View substance registered dossier
3-phenylpropyldimethoxymethylsilan
418-750-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
3-R(-)acetoxy-1-azabicyclo[2.2.2]octane tartrate dihydrate
941-989-7 - Active Intermediate Joint Intermediate use only 16-11-2017 View substance registered dossier
3-sec-[C15-18-(branched and linear)-alk-2-enyl]pyrrolidine-2,5-dione
701-350-3 - null Full Individual 10 - 100 tonnes per annum 05-08-2020 View substance registered dossier
3-Sulfanyl-1-hexanol
922-990-1 - Active Intermediate Individual Intermediate use only 28-03-2017 View substance registered dossier
3-sulfinobenzoic acid
416-000-2 - Active NONS Joint Tonnage data confidential 29-07-2011 View substance registered dossier
3-{5-[3-(4-{1-[3-(dimethylammonio)propyl]-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo}benzamido)phenylazo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-pyridyl}propyl(dimethyl)ammonium di(acetate); 3-{5-[4-(3-{1,6-dihydro-2-hydroxy-4-methyl-1-[3-(methylammonio)propyl]-6-oxo-3-pyridylazo}benzamido]phenylazo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-pyridyl}propyl(dimethyl)ammonium di(acetate); reaction mass of: 3-{5-[3-(4-{1,6-dihydro-2-hydroxy-4-methyl-1-[3-(methylammonio)propyl]-6-oxo-3-pyridylazo}benzamido)phenylazo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-pyridyl}propyl(methyl)ammonium di(acetate)
431-440-5 - Active Full Joint ≥ 1 to < 10 tonnes 18-10-2019 View substance registered dossier
3-{5-[3-(4-{1-[3-(dimethylammonio)propyl]-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo}benzamido)phenylazo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-pyridyl}propyl(dimethyl)ammonium di(acetate); 3-{5-[4-(3-{1,6-dihydro-2-hydroxy-4-methyl-1-[3-(methylammonio)propyl]-6-oxo-3-pyridylazo}benzamido]phenylazo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-pyridyl}propyl(dimethyl)ammonium di(acetate); reaction mass of: 3-{5-[3-(4-{1,6-dihydro-2-hydroxy-4-methyl-1-[3-(methylammonio)propyl]-6-oxo-3-pyridylazo}benzamido)phenylazo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-pyridyl}propyl(methyl)ammonium di(acetate)
431-440-5 - Cease Manufacture NONS Joint Cease manufacture 15-12-2008 View substance registered dossier
3-{[alkyl(dimethyl)silyl]substituted}estratetraen-17-one
- - Active Intermediate Joint Intermediate use only 06-11-2020 View substance registered dossier
3-{[Alkyl(dimethyl)silyl]substituted}estratrien-17-one
- - Active Intermediate Joint Intermediate use only 06-11-2020 View substance registered dossier
3-{[tert-butyl(diakyl)silyl]oxy}-17-[(triakylsilyl)oxy]estratrienediol
- - Active Intermediate Joint Intermediate use only 06-11-2020 View substance registered dossier
327 QRN
424-580-3 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
350CD0001
436-940-7 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
3940W92
425-610-8 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
39947_Reaction mass of 1-(3-((C12-18-(even numbered))-alkyl-amino)propyl)guanidine acetate salt and 1-(C12-18-(even numbered))-alkyl-1-(3-guanidinopropyl)guanidine acetate salt and 1-(C12-18-(even numbered))-alkyl-tetrahydropyrimidin-2(1H)-imine acetate salt
939-650-3 - null Full Joint 100 - 1 000 tonnes per annum 25-08-2020 View substance registered dossier
3G3 RESIN
443-110-8 - null NONS Individual Tonnage Data Confidential 25-08-2020 View substance registered dossier
3M (TM) SPECIALTY GAS PFG-3480
440-180-1 - Active NONS Joint Tonnage data confidential 14-03-2011 View substance registered dossier
4''-butyl-4-[difluoro(3,4,5-trifluorophenoxy)methyl]-2',3,5-trifluoro-1,1':4',1''-terphenyl
935-976-5 - Active Full Joint ≥ 0 to < 10 tonnes 16-10-2019 View substance registered dossier
4''-ethyl-2'-fluoro-[1,1':4',1''-terphenyl]-4-methanol
936-118-2 - null Full Joint 0 - 10 tonnes per annum 27-09-2020 View substance registered dossier
4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile
480-420-2 - Active Intermediate Individual Intermediate use only 14-12-2012 View substance registered dossier
4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile
480-420-2 - Active Intermediate Joint Intermediate use only 03-12-2020 View substance registered dossier
4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile
480-420-2 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
4'-Ethyl-2,3-difluorbiphenyl
929-069-3 - Active Intermediate Joint Intermediate use only 11-04-2018 View substance registered dossier
4'-Methyl-4-(E)-pent-3-enyl-biphenyl
473-310-0 - Active Full Joint ≥ 0 to < 10 tonnes 30-03-2020 View substance registered dossier
4'-trans-ethyl-[1,1'-bicyclohexyl]-4-one
485-460-4 - Active NONS Joint Tonnage data confidential 13-09-2019 View substance registered dossier
4,4'-(2,3-epoxypropoxy)-2,2'- dimethyl-5,5'-tert-butyldiphenylsulphide
441-520-1 - Active Full Joint ≥ 1 to < 10 tonnes 10-09-2018 View substance registered dossier
4,4'-[(6S)-6-phenylindolo[1,2-c][1,3]benzoxazine-3,10-diyl]bis{2-[(2S)-2-pyrrolidiniumyl]-1H-imidazol-3-ium} tetrachloride
944-036-3 - Active Intermediate Individual Intermediate use only 21-10-2016 View substance registered dossier
4,4'-[1,2-ethenediylbis[(3-sulfo-4,1-phenylene)imino[6-[bis(2-hydroxyethyl)amino]-1,3,5-triazine-4,2-diyl]imino]]bisarenoate sodium salt
- - Active Full Individual ≥ 1 000 to < 10 000 tonnes 23-07-2013 View substance registered dossier
4,4'-bis(2-methyl-2-(4-methylphenyl)-1-propionyl)diphenylsulfide
415-410-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4,4'-carbonylbis[2-({[3-(triethoxysilyl)propyl]amino}carbonyl)benzoic acid]
419-190-5 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4,4'-methylene bis(3-chloro-2,6-di-ethylphenylisocyanate)
420-530-1 - No longer Valid NONS Individual No longer valid 15-12-2008 View substance registered dossier
4,4'-methylenediphenyl diisocyanate and its oligomeric reaction products with oxydipropanol and [(methylethylene)bis(oxy)]dipropanol
701-072-2 - Active Full Joint ≥ 1 000 to < 10 000 tonnes 15-02-2019 View substance registered dossier
4,4'-Methylenediphenyl diisocyanate, oligomeric reaction products with butane-1,3-diol, 2,4'-diisocyanatodiphenylmethane, 1,1'-methylenebis(4-isocyanatobenzene) homopolymer, [(methylethylene)bis(oxy)]dipropanol and propane-1,2-diol
500-313-7 - Active Full Joint ≥ 1 000 to < 10 000 tonnes 01-03-2019 View substance registered dossier
4,4'-methylenediphenyldiisocyanate and 2,4'-diisocyanatodiphenylmethane and their oligomerisation reaction products with 2,2'-oxydiethanol, propane-1,2-diol and butane-1,3-diol
701-276-1 - Cease Manufacture Full Joint Cease manufacture 13-02-2019 View substance registered dossier
4,4’-isopropylidenediphenol, reaction products with 1-chloro-2,3-epoxypropane, mono, di and triesters with acrylic acid
948-054-2 - Active Full Joint ≥ 1 to < 10 tonnes 21-10-2019 View substance registered dossier
4,5-di-tert-butyl-6-ethoxy-2,2-dimethyl-3,7-dioxa-4-aza-6-phosphanonan-1-oic acid 6-oxide
449-920-8 - Active NONS Individual Tonnage data confidential 16-12-2010 View substance registered dossier
4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol
443-400-4 - null NONS Individual Tonnage Data Confidential 25-08-2020 View substance registered dossier
4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol
443-400-4 - Active Intermediate Joint Intermediate use only 20-08-2018 View substance registered dossier
4,7-methanooctahydro-1H-indene-diyldimethyl bis(2-carboxybenzoate)
407-410-2 - Active Full Individual ≥ 100 to < 1 000 tonnes 08-12-2016 View substance registered dossier
4,7-methanooctahydro-1H-indene-diyldimethyl bis(2-carboxybenzoate)
407-410-2 - Active NONS Joint Tonnage data confidential 09-11-2011 View substance registered dossier
4-(1-((3-((2-(tert-butoxycarbonyl(methyl)amino)acetoxy)methyl)pyridin-2-yl)(methyl)carbamoyloxy)ethyl)-1-((2R,3S)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-1H-1,2,4-triazol-4-ium)hemisulphate
926-418-1 - Active Intermediate Individual Intermediate use only 09-05-2018 View substance registered dossier
4-(2-aminoethyl)indole, fumarate
947-445-5 - Active Intermediate Joint Intermediate use only 07-05-2018 View substance registered dossier
4-(2-carboxymethylthio)ethoxy-1-hydroxy-5-isobutyloxycarbonylamino-N-(3-dodecyloxypropyl)-2-naphthamide
420-730-7 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
4-(2-Hydroxyethyl)indolin-2-one
925-636-4 - null Intermediate Individual Intermediate Use Only 26-06-2020 View substance registered dossier
4-(2-{(E)-2-[(1E)-2-chloro-1-{(2E)-2-[1,1-dimethyl-3-(4-sulfobutyl)-1,3-dihydro-2H-benzo[e]indol-2-ylidene]ethylidene}-1H-inden-3-yl]vinyl}-1,1-dimethyl-1H-benzo[e]indolium-3-yl)butane-1-sulfonate
942-705-4 - Active Full Individual ≥ 1 to < 10 tonnes 14-06-2016 View substance registered dossier
4-(3,4-DICHLOROPHENYL)-3,4-DIHYDRO-1-(2H)-NAPHTHALENONE
406-300-1 - Active NONS Joint Tonnage data confidential 20-08-2010 View substance registered dossier
4-(3,4-DICHLOROPHENYL)-3,4-DIHYDRO-1-(2H)-NAPHTHALENONE
406-300-1 - Active Intermediate Joint Intermediate use only 15-02-2018 View substance registered dossier
4-(4'-Trifluoromethylphenyl)benzaldehyde
473-430-3 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
4-(4,6-Bis((biphenyl-4-yl)-1,3,5-triazine-2-yl)-1,3-benzodiole
485-420-6 - Active Full Joint ≥ 10 to < 100 tonnes 16-05-2012 View substance registered dossier
4-(4,6-Bis((biphenyl-4-yl)-1,3,5-triazine-2-yl)-1,3-benzodiole
485-420-6 - Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
4-(4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1-butynyl)-.alpha.,.alpha.-dimethylbenzeneacetic acid
462-560-6 - Active Intermediate Joint Intermediate use only 06-07-2015 View substance registered dossier
4-(4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1-butynyl)-.alpha.,.alpha.-dimethylbenzeneacetic acid
462-560-6 - No longer Valid Intermediate Individual No longer valid 10-05-2011 View substance registered dossier
4-(4-aminoanilino)-6-[3-(dibutylamino)propylamino]-heteromonocyclic-2-ol
427-670-0 - Active Full Joint ≥ 1 tonnes 24-03-2016 View substance registered dossier
4-(4-Brom-5-ethyl-tetrahydropyran-2-yl)-phenol
919-822-4 - Active Intermediate Joint Intermediate use only 25-05-2018 View substance registered dossier
4-(4-Brom-5-propyl-tetrahydropyran-2-yl)-phenol
917-991-9 - Active Intermediate Joint Intermediate use only 16-02-2018 View substance registered dossier
4-(4-chloro-3-nitro-phenyl)-3-methyl-4-oxo-butanoic acid
918-019-6 - null Intermediate Joint Intermediate Use Only 04-05-2020 View substance registered dossier
4-(4-chlorophenyl)-1-imidazol-1-ylbutan-2-ol
925-590-5 - Active Intermediate Joint Intermediate use only 16-01-2017 View substance registered dossier
4-(4-hydroxyphenyl)cyclohexanone
423-920-8 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
4-(4-trans-propylcylohexyl)phenol
440-740-5 - Active Intermediate Joint Intermediate use only 20-12-2019 View substance registered dossier
4-(4-trans-vinyl-[1,1'-bicyclohexyl]-4'-trans-yl)-1,2-difluorobenzene
430-860-6 - null NONS Individual Tonnage Data Confidential 22-05-2020 View substance registered dossier
4-(5-(5-[1-(4-carboxyphenyl)hexahydro-2,4,6-trioxopyrimidin-5-ylidene]penta-1,3-dienyl)-1,2,3,4-tetrahydro-6-hydroxy-2,4-dioxopyrimidin-1-yl)benzoic acid-triethylamine salt
426-900-7 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-(5-ethoxyheptyl)perhydropentalen-2-one
419-880-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-(5-Ethyl-tetrahydropyran-2-yl)-phenol
921-114-5 - Active Full Joint ≥ 0 to < 10 tonnes 23-10-2020 View substance registered dossier
4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide
448-010-8 - Active Intermediate Joint Intermediate use only 20-08-2018 View substance registered dossier
4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide
448-010-8 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
4-(5-Propyl-tetrahydropyran-2-yl)-phenol
919-949-5 - Active Full Joint ≥ 1 to < 10 tonnes 04-04-2018 View substance registered dossier
4-(6-(3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile bis sulphate
951-814-6 - Active Intermediate Individual Intermediate use only 03-01-2020 View substance registered dossier
4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester)
425-880-7 - Active Full Joint ≥ 1 to < 10 tonnes 21-05-2019 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
MOEHS CANTABRA P.I.Requejada Z-23 39313 Polanco Cantabria Spain - - 3-Amino-tricyclo[3,3,1,13,7]decan-1-ol 450-050-6 - - View substance registered dossier
- - - - 3-Amino-tricyclo[3,3,1,13,7]decan-1-ol 450-050-6 - - View substance registered dossier
Novartis International Pharmaceutical ltd., Branch Ireland Ringaskiddy IE Ringaskiddy Cork Ireland - - 3-Amino-tricyclo[3,3,1,13,7]decan-1-ol 450-050-6 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy - - 3-Amino-tricyclo[3,3,1,13,7]decan-1-ol 450-050-6 - - View substance registered dossier
ADAMA Agriculture BV Arnhemseweg 87 Postbus 355 3830 AK Leusden Netherlands - - 3-bromo-1-(3-chloropyrid-2-yl)-5-methyl-1H-pyrazole 952-948-8 - - View substance registered dossier
Covance Clinical Development SA 040 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Active 3-C12-14-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 931-324-9 - - View substance registered dossier
Kapachim S.A. El. Venizelou 128, N. Ionia 14231 Athens Attiki Greece Greece Active 3-C12-14-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 931-324-9 - - View substance registered dossier
Kao Corporation, S.A. Puig dels Tudons, 10 08210 Barbera del Valles Barcelona Spain Spain Active 3-C12-14-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 931-324-9 - 2011; 2012; 2014 View substance registered dossier
EARTH FRIENDLY PRODUCTS HELLAS LTD 69 Solonos str 10679 Athens Attica Greece Greece Active 3-C12-14-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 931-324-9 - 2018 View substance registered dossier
STEPAN EUROPE SA Chemin JONGKIND 38340 VOREPPE France France Cease Manufacture 3-C12-14-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 931-324-9 - 2018 View substance registered dossier
Covance Clinical Development SA 039 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Active 3-C12-14-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 931-324-9 - 2012 View substance registered dossier
Enaspol a.s. Velvety 79 41501 Teplice 1 Czech Republic Czech Republic Active 3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 939-581-9 - - View substance registered dossier
Solvay P&S GmbH Hans-Boeckler-Allee 20 30173 Hannover Germany Germany Active 3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 939-581-9 - - View substance registered dossier
ZSCHIMMER & SCHWARZ ITALIANA S.p.A. Via Angelo Ariotto No. 1 13038 TRICERRO (VERCELLI) Italy Italy Active 3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 939-581-9 - - View substance registered dossier
Solvay P&S GmbH-1 Engesserstrasse 79108 Freiburg Germany Germany Active 3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 939-581-9 - - View substance registered dossier
EOC Surfactants NV Durmakker 35 B 9940 Evergem Oost Vlaanderen Belgium Belgium Active 3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 939-581-9 - 2013; 2014; 2015; 2017 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active 3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 939-581-9 - 2015 View substance registered dossier
INNOSPEC PERFORMANCE CHEMICALS SPAIN S.L. Polígono Zona Franca Sector F, Calle 43 Nº 10 8040 Barcelona Spain Spain Active 3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 939-581-9 - 2014 View substance registered dossier
Evonik Italia S.r.l. Via Falconera, 7 26025 Pandino (CR) Italy Italy Active 3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 939-581-9 - 2015 View substance registered dossier
EOC Belgium nv Industriepark De Bruwaan 24 9700 Oudenaarde Belgium Belgium Active 3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 939-581-9 - - View substance registered dossier
SC39 Libra Speciality Chemicals Długosza 67 43-188 Orzesze Poland Poland Active 3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 939-581-9 - - View substance registered dossier
Przedsiębiorstwo Produkcyjno-Usługowe CHEMCO sp. z o.o. Kosciuszki 19 83-033 Sobowidz Poland Poland Active 3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 939-581-9 - 2018 View substance registered dossier
FARMAK, a.s. Na vlcinci 16/3 779 00 Olomouc Czech Republic Czech Republic Active 3-cyanomethyl-2-(4-methylphenyl)-6-methylimidozo[1,2-a]pyridine 457-480-3 - 2009; 2011 View substance registered dossier
ORGANICA Feinchemie GmbH Wolfen Ortsteil Wolfen Kunstseidestraße 5 06766 Bitterfeld-Wolfen Germany - - 3-Cyclohexyl-2-cyclohexylimino-5-(4-diethylamino-2-methoxyphenyl)methylenoxazolidine-4-one 457-890-2 - - View substance registered dossier
- - - - 3-Cyclohexyl-2-cyclohexylimino-5-(4-diethylamino-2-methoxyphenyl)methylenoxazolidine-4-one 457-890-2 - - View substance registered dossier
Novartis Grimsby Limited Moody Lane, Pyewipe DN31 2SR Grimsby N.E. Lincolnshire United Kingdom United Kingdom Active 3-Dimethylamino-1-(pyrid-3-yl)-2-propen-1-one 434-770-8 - 2010 View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active 3-Dimethylamino-1-(pyrid-3-yl)-2-propen-1-one 434-770-8 - - View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany - - 3-Ethoxy-(E)-2-propenoic acid ethyl ester 443-080-6 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 3-ethoxy-4,6-difluoro-7-hexyloxy-dibenzothiophene 950-069-4 - - View substance registered dossier
Yordas GmbH Äußere Nürnberger Str. 62, 91301 Forchheim Germany Germany Active 3-ethyl-1-methyl-1H-imidazol-3-ium 4-(C11-13-sec-alkyl benzenesulfonates) 940-820-4 - 2018 View substance registered dossier
SCAS Europe S.A./N.V. Leonardo Da Vincilaan 19 B-1831 Diegem Belgium Belgium Active 3-ethyl-3-[(2-ethylhexyloxy)methyl]oxetane 445-460-7 - 2012 View substance registered dossier
URQUIMA S.A. AVDA. CAMÍ REIAL, 51 -57 08184 PALAU-SOLITÀ I PLEGAMANS CATALUNYA Spain Spain Active 3-Ethyl-4-methyl-2-oxo-2,5-dihydropyrrole-1-carboxylic acid phenethylamide 925-067-1 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 3-Fluor-4'-propylbiphenyl 923-509-8 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 3-fluoro-4'-(trans-4-propylcyclohexyl)-1,1'-biphenyl 936-120-3 - 2018; 2020 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 3-fluoro-4'-pentyl-1,1'-biphenyl 935-974-4 - - View substance registered dossier
JSC "Olainfarm" Rupnicu str. 5 LV-2114 Olaine Latvia Latvia Active 3-hydroxy-3-carbethoxy-1-azabicyclo[2.2.2]octane 925-046-7 - - View substance registered dossier
Evonik Operations GmbH - ME01 Rellinghauser Straße 1-11 45128 Essen Germany - - 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 - - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany - - 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 - - View substance registered dossier
Recticel NV Olympiadenlaan 2 1140 Brussel Belgium - - 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 - - View substance registered dossier
Vencorex France_1 196 Allée Alexandre Borodine 69800 Saint Priest France - - 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 - - View substance registered dossier
Covestro Deutschland AG Kaiser-Wilhelm-Allee 60 51373 Leverkusen Germany - - 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 - - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, uretdione type 938-351-5 - 2016; 2017 View substance registered dossier
Covestro Deutschland AG Kaiser-Wilhelm-Allee 60 51373 Leverkusen Germany Germany Active 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate, oligomers reaction product with 3-(cyclohexylamino)propane-1-sulfonic acid and N,N-dimethylcyclohexanamine 926-601-6 - 2016 View substance registered dossier
BASF Coatings GmbH Glasuritstrasse 1 Postfach 6123 48136 Münster Nordrhein-Westfalen Germany Germany Active 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate, oligomers, 2-Hydroxy-1(2)- methylethyl carbamate blocked 921-910-2 - 2018; 2020 View substance registered dossier
B-Lands Consulting (8111198-8) World Trade Center, 5 Place Robert Schuman - BP 1510 38025 Grenoble France France France Active 3-Mercaptopropyl-functionalized silica gel 945-952-6 - 2018 View substance registered dossier
Kuraray Europe GmbH (OR1) Philipp-Reis-Str. 4 65795 Hattersheim Germany Germany Active 3-methyl-1,3-butandiol 459-270-7 - 2011; 2012; 2020 View substance registered dossier
Evonik Fermas s.r.o. Slovenská Ľupča 938 976 13 Slovenská Ľupča Slovakia Slovakia Cease Manufacture 3-methyl-2-oxobutanoic acid, fermentation products 931-029-5 - 2017 View substance registered dossier
OMNOVA Solutions SAS (OR of OMNOVA Solutions Inc) 14 avenue des Tropiques ZA de Courtaboeuf 2, Villejust 91955 Courtaboeuf Cedex France France Active 3-methyl-3-(2,2,3,3,3-pentafluoropropoxy)methyl oxetane 482-280-8 - 2019; 2020 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 3-methyl-3-(2,2,3,3,3-pentafluoropropoxy)methyl oxetane 482-280-8 - - View substance registered dossier
CENTIPHARM Chemin de la Madeleine 06131 GRASSE FRANCE France France Active 3-Methyl-4-(4-trifluoromethylsulfanyl-phenoxy)-phenylamine oxalate 929-675-8 - - View substance registered dossier
Central Glass Germany GmbH Kantstrasse 2 33790 Halle/Westf. Nordrhein Westfalen Germany Germany Active 3-methyl-4-oxo-4-(3-nitro-4-chlorophenyl)butanoic acid 440-860-8 - - View substance registered dossier
DKSH Marketing Services Spain, S.A.U. Santaló 152-154 baixos 08021 Barcelona Catalonia Spain Spain Active 3-methyl-4-oxo-4-(3-nitro-4-chlorophenyl)butanoic acid 440-860-8 - - View substance registered dossier
All'Chem rue Marceau 03108 MONTLUCON CEDEX France France Active 3-methyl-4-oxo-4-(3-nitro-4-chlorophenyl)butanoic acid 440-860-8 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 3-methyl-5-phenylmethoxy-2-(4-phenylmethoxyphenyl)-1H-indole 926-072-1 - - View substance registered dossier
NOVEAL 16 rue Maurice Berteaux 95500 LE THILLAY France France Active 3-oxyde-2,4-pyrimidinediamine monohydrate 419-140-2 - 2010 View substance registered dossier
[Confidential] - - - 3-oxyde-2,4-pyrimidinediamine monohydrate 419-140-2 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 3-phenylpropyldimethoxymethylsilan 418-750-6 - - View substance registered dossier
JSC "Olainfarm" Rupnicu str. 5 LV-2114 Olaine Latvia Latvia Active 3-R(-)acetoxy-1-azabicyclo[2.2.2]octane tartrate dihydrate 941-989-7 - - View substance registered dossier
Afton Chemical S.P.R.L. (Woluwe) Alma Court Lenneke Marelaan, 8 B-1932 St-Stevens-Woluwe Belgium - - 3-sec-[C15-18-(branched and linear)-alk-2-enyl]pyrrolidine-2,5-dione 701-350-3 - - View substance registered dossier
ORGANICA Feinchemie GmbH Wolfen Ortsteil Wolfen Kunstseidestraße 5 06766 Bitterfeld-Wolfen Germany Germany Active 3-Sulfanyl-1-hexanol 922-990-1 - - View substance registered dossier
FUJIFILM Belgium NV Europark Noord 21-22 9100 Sint-Niklaas Belgium Belgium Active 3-sulfinobenzoic acid 416-000-2 - 2011 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 3-sulfinobenzoic acid 416-000-2 - - View substance registered dossier
ARCHROMA IBÉRICA, S.L. ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain Spain Active 3-{5-[3-(4-{1-[3-(dimethylammonio)propyl]-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo}benzamido)phenylazo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-pyridyl}propyl(dimethyl)ammonium di(acetate); 3-{5-[4-(3-{1,6-dihydro-2-hydroxy-4-methyl-1-[3-(methylammonio)propyl]-6-oxo-3-pyridylazo}benzamido]phenylazo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-pyridyl}propyl(dimethyl)ammonium di(acetate); reaction mass of: 3-{5-[3-(4-{1,6-dihydro-2-hydroxy-4-methyl-1-[3-(methylammonio)propyl]-6-oxo-3-pyridylazo}benzamido)phenylazo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-pyridyl}propyl(methyl)ammonium di(acetate) 431-440-5 - 2019 View substance registered dossier
Archroma Italy, S.r.l. Via Manzoni 37 20030 Palazzolo Milanese Italy Italy Cease Manufacture 3-{5-[3-(4-{1-[3-(dimethylammonio)propyl]-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo}benzamido)phenylazo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-pyridyl}propyl(dimethyl)ammonium di(acetate); 3-{5-[4-(3-{1,6-dihydro-2-hydroxy-4-methyl-1-[3-(methylammonio)propyl]-6-oxo-3-pyridylazo}benzamido]phenylazo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-pyridyl}propyl(dimethyl)ammonium di(acetate); reaction mass of: 3-{5-[3-(4-{1,6-dihydro-2-hydroxy-4-methyl-1-[3-(methylammonio)propyl]-6-oxo-3-pyridylazo}benzamido)phenylazo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-pyridyl}propyl(methyl)ammonium di(acetate) 431-440-5 - 2017 View substance registered dossier
Archroma Italy, S.r.l. - OR Via Manzoni 37 20030 Palazzolo Milanese Italy Italy Cease Manufacture 3-{5-[3-(4-{1-[3-(dimethylammonio)propyl]-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo}benzamido)phenylazo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-pyridyl}propyl(dimethyl)ammonium di(acetate); 3-{5-[4-(3-{1,6-dihydro-2-hydroxy-4-methyl-1-[3-(methylammonio)propyl]-6-oxo-3-pyridylazo}benzamido]phenylazo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-pyridyl}propyl(dimethyl)ammonium di(acetate); reaction mass of: 3-{5-[3-(4-{1,6-dihydro-2-hydroxy-4-methyl-1-[3-(methylammonio)propyl]-6-oxo-3-pyridylazo}benzamido)phenylazo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-1-pyridyl}propyl(methyl)ammonium di(acetate) 431-440-5 - 2017 View substance registered dossier
[Confidential] - - - 3-{[alkyl(dimethyl)silyl]substituted}estratetraen-17-one - - - View substance registered dossier
[Confidential] - - - 3-{[Alkyl(dimethyl)silyl]substituted}estratrien-17-one - - - View substance registered dossier
[Confidential] - - - 3-{[tert-butyl(diakyl)silyl]oxy}-17-[(triakylsilyl)oxy]estratrienediol - - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active 327 QRN 424-580-3 - - View substance registered dossier
- - - - 327 QRN 424-580-3 - - View substance registered dossier
BASF Coatings GmbH Glasuritstrasse 1 Postfach 6123 48136 Münster Nordrhein-Westfalen Germany Germany Cease Manufacture 350CD0001 436-940-7 - 2018 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 3940W92 425-610-8 - - View substance registered dossier
Lonza Cologne GmbH - REACH Nattermannallee 1 50829 Cologne Germany - - 39947_Reaction mass of 1-(3-((C12-18-(even numbered))-alkyl-amino)propyl)guanidine acetate salt and 1-(C12-18-(even numbered))-alkyl-1-(3-guanidinopropyl)guanidine acetate salt and 1-(C12-18-(even numbered))-alkyl-tetrahydropyrimidin-2(1H)-imine acetate salt 939-650-3 - - View substance registered dossier
Clariant Produkte (Deutschland) GmbH Am Unisys-Park 1 65843 Sulzbach am Taunus Germany - - 39947_Reaction mass of 1-(3-((C12-18-(even numbered))-alkyl-amino)propyl)guanidine acetate salt and 1-(C12-18-(even numbered))-alkyl-1-(3-guanidinopropyl)guanidine acetate salt and 1-(C12-18-(even numbered))-alkyl-tetrahydropyrimidin-2(1H)-imine acetate salt 939-650-3 - - View substance registered dossier
Merck Performance Materials GmbH Rheingaustrasse 190-196 65203 Wiesbaden Germany - - 3G3 RESIN 443-110-8 - - View substance registered dossier
3M Belgium BVBA/SPRL Hermeslaan 7 1831 Diegem Belgium Belgium Active 3M (TM) SPECIALTY GAS PFG-3480 440-180-1 - 2011 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active 3M (TM) SPECIALTY GAS PFG-3480 440-180-1 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4''-butyl-4-[difluoro(3,4,5-trifluorophenoxy)methyl]-2',3,5-trifluoro-1,1':4',1''-terphenyl 935-976-5 - 2019 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany - - 4''-ethyl-2'-fluoro-[1,1':4',1''-terphenyl]-4-methanol 936-118-2 - - View substance registered dossier
AGC Pharma Chemicals Europe, S.L.U. Camí de la Pomereda, 13 08380 Malgrat de Mar (Barcelona) Spain Spain Active 4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile 480-420-2 - - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active 4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile 480-420-2 - - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Cease Manufacture 4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile 480-420-2 - 2015 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4'-Ethyl-2,3-difluorbiphenyl 929-069-3 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4'-Methyl-4-(E)-pent-3-enyl-biphenyl 473-310-0 - 2010; 2020 View substance registered dossier
WeylChem InnoTec GmbH Alt-Fechenheim 34 60386 Frankfurt am Main Hesse Germany Germany Active 4'-Methyl-4-(E)-pent-3-enyl-biphenyl 473-310-0 - 2009; 2018 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4'-trans-ethyl-[1,1'-bicyclohexyl]-4-one 485-460-4 - 2019 View substance registered dossier
ExponentOR35I Block 1, Blanchardstown Corporate Park Ballycoolen Road, Blanchardstown D15 AKK1 Dublin Ireland Ireland Active 4,4'-(2,3-epoxypropoxy)-2,2'- dimethyl-5,5'-tert-butyldiphenylsulphide 441-520-1 - 2018 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 4,4'-[(6S)-6-phenylindolo[1,2-c][1,3]benzoxazine-3,10-diyl]bis{2-[(2S)-2-pyrrolidiniumyl]-1H-imidazol-3-ium} tetrachloride 944-036-3 - - View substance registered dossier
[Confidential] - - - 4,4'-[1,2-ethenediylbis[(3-sulfo-4,1-phenylene)imino[6-[bis(2-hydroxyethyl)amino]-1,3,5-triazine-4,2-diyl]imino]]bisarenoate sodium salt - - - View substance registered dossier
- - - - 4,4'-bis(2-methyl-2-(4-methylphenyl)-1-propionyl)diphenylsulfide 415-410-9 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active 4,4'-carbonylbis[2-({[3-(triethoxysilyl)propyl]amino}carbonyl)benzoic acid] 419-190-5 - - View substance registered dossier
Lonza Biologics PLC The Courtyard, Severn Drive GL20 8GD Tewkesbury Gloucestershire United Kingdom United Kingdom No longer Valid 4,4'-methylene bis(3-chloro-2,6-di-ethylphenylisocyanate) 420-530-1 - 2021 View substance registered dossier
DOW ITALIA S.R.L. Via F. Albani 65 20148 Milano Italy Italy Active 4,4'-methylenediphenyl diisocyanate and its oligomeric reaction products with oxydipropanol and [(methylethylene)bis(oxy)]dipropanol 701-072-2 - 2019 View substance registered dossier
DOW BENELUX B.V. Postbus 48 4530 AA Terneuzen Netherlands Netherlands Active 4,4'-methylenediphenyl diisocyanate and its oligomeric reaction products with oxydipropanol and [(methylethylene)bis(oxy)]dipropanol 701-072-2 - 2012; 2014; 2016; 2017; 2019 View substance registered dossier
Huntsman (Europe) BV - OR2 Everslaan 45 B-3078 Everberg Belgium Belgium Active 4,4'-Methylenediphenyl diisocyanate, oligomeric reaction products with butane-1,3-diol, 2,4'-diisocyanatodiphenylmethane, 1,1'-methylenebis(4-isocyanatobenzene) homopolymer, [(methylethylene)bis(oxy)]dipropanol and propane-1,2-diol 500-313-7 - 2017; 2019 View substance registered dossier
HUNTSMAN HOLLAND BV Merseyweg 10 3197 KG Botlek-Rotterdam Netherlands Netherlands Active 4,4'-Methylenediphenyl diisocyanate, oligomeric reaction products with butane-1,3-diol, 2,4'-diisocyanatodiphenylmethane, 1,1'-methylenebis(4-isocyanatobenzene) homopolymer, [(methylethylene)bis(oxy)]dipropanol and propane-1,2-diol 500-313-7 - 2011; 2012; 2013; 2015; 2019 View substance registered dossier
BASF Polyurethanes GmbH Elastogranstr. 60 49448 Lemförde Niedersachsen Germany Germany Cease Manufacture 4,4'-methylenediphenyldiisocyanate and 2,4'-diisocyanatodiphenylmethane and their oligomerisation reaction products with 2,2'-oxydiethanol, propane-1,2-diol and butane-1,3-diol 701-276-1 - 2020 View substance registered dossier
BASF Espanola S.L. Calle Can Ràbia, n. 3-5 8017 Barcelona Spain Spain Cease Manufacture 4,4'-methylenediphenyldiisocyanate and 2,4'-diisocyanatodiphenylmethane and their oligomerisation reaction products with 2,2'-oxydiethanol, propane-1,2-diol and butane-1,3-diol 701-276-1 - 2020 View substance registered dossier
Yordas GmbH Äußere Nürnberger Str. 62, 91301 Forchheim Germany Germany Active 4,4’-isopropylidenediphenol, reaction products with 1-chloro-2,3-epoxypropane, mono, di and triesters with acrylic acid 948-054-2 - 2019 View substance registered dossier
ARKEMA FRANCE 420 rue d'Estienne d'Orves 92700 COLOMBES France France Active 4,5-di-tert-butyl-6-ethoxy-2,2-dimethyl-3,7-dioxa-4-aza-6-phosphanonan-1-oic acid 6-oxide 449-920-8 - 2010 View substance registered dossier
- - - - 4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol 443-400-4 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active 4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol 443-400-4 - 2016 View substance registered dossier
Piramal Healthcare UK Ltd Whalton Road NE61 3YA Morpeth Northumberland United Kingdom United Kingdom Active 4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol 443-400-4 - - View substance registered dossier
ELIX Polymers, S.L. Poligono Industrial s/n Ctra. de Vilaseca - La Pineda 43006 Tarragona Spain Spain Active 4,7-methanooctahydro-1H-indene-diyldimethyl bis(2-carboxybenzoate) 407-410-2 - 2016 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 4,7-methanooctahydro-1H-indene-diyldimethyl bis(2-carboxybenzoate) 407-410-2 - - View substance registered dossier
INEOS Styrolution Köln GmbH Alte Str. 201 50769 Köln NRW Germany Germany Active 4,7-methanooctahydro-1H-indene-diyldimethyl bis(2-carboxybenzoate) 407-410-2 - 2011 View substance registered dossier
[Confidential] - - - 4-(1-((3-((2-(tert-butoxycarbonyl(methyl)amino)acetoxy)methyl)pyridin-2-yl)(methyl)carbamoyloxy)ethyl)-1-((2R,3S)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-1H-1,2,4-triazol-4-ium)hemisulphate 926-418-1 - - View substance registered dossier
URQUIMA S.A. AVDA. CAMÍ REIAL, 51 -57 08184 PALAU-SOLITÀ I PLEGAMANS CATALUNYA Spain Spain Active 4-(2-aminoethyl)indole, fumarate 947-445-5 - - View substance registered dossier
FujiFilm Manufacturing Europe BV Oudenstaart 1 5047 TK Tilburg Netherlands Netherlands Cease Manufacture 4-(2-carboxymethylthio)ethoxy-1-hydroxy-5-isobutyloxycarbonylamino-N-(3-dodecyloxypropyl)-2-naphthamide 420-730-7 - 2019 View substance registered dossier
Thermofisher Scientific Cork Ltd. Currabinny P43 AY66 Carrigaline Co. Cork Ireland - - 4-(2-Hydroxyethyl)indolin-2-one 925-636-4 - - View substance registered dossier
Agfa-Gevaert N.V. Septestraat 27 2640 Mortsel Belgium Belgium Active 4-(2-{(E)-2-[(1E)-2-chloro-1-{(2E)-2-[1,1-dimethyl-3-(4-sulfobutyl)-1,3-dihydro-2H-benzo[e]indol-2-ylidene]ethylidene}-1H-inden-3-yl]vinyl}-1,1-dimethyl-1H-benzo[e]indolium-3-yl)butane-1-sulfonate 942-705-4 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active 4-(3,4-DICHLOROPHENYL)-3,4-DIHYDRO-1-(2H)-NAPHTHALENONE 406-300-1 - - View substance registered dossier
FINORGA SAS 497 route de Givors 38670 CHASSE SUR RHONE France France Active 4-(3,4-DICHLOROPHENYL)-3,4-DIHYDRO-1-(2H)-NAPHTHALENONE 406-300-1 - 2010 View substance registered dossier
MOEHS BCN, S.L. C/ Zenc, 12 08755 Castellbisbal Barcelona Spain Spain Active 4-(3,4-DICHLOROPHENYL)-3,4-DIHYDRO-1-(2H)-NAPHTHALENONE 406-300-1 - - View substance registered dossier
Aceto France 3 Place Giovanni da Verrazzano 69009 Lyon France France Active 4-(3,4-DICHLOROPHENYL)-3,4-DIHYDRO-1-(2H)-NAPHTHALENONE 406-300-1 - 2017 View substance registered dossier
MOEHS CATALANA Cesar Martinell i Brunet 12 A 08191 Rubi Barcelona Spain Spain Active 4-(3,4-DICHLOROPHENYL)-3,4-DIHYDRO-1-(2H)-NAPHTHALENONE 406-300-1 - - View substance registered dossier
- - - - 4-(4'-Trifluoromethylphenyl)benzaldehyde 473-430-3 - - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Cease Manufacture 4-(4,6-Bis((biphenyl-4-yl)-1,3,5-triazine-2-yl)-1,3-benzodiole 485-420-6 - 2019 View substance registered dossier
BASF Lampertheim GmbH Chemiestrasse 22 68619 Lampertheim Germany Germany Active 4-(4,6-Bis((biphenyl-4-yl)-1,3,5-triazine-2-yl)-1,3-benzodiole 485-420-6 - 2012 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 4-(4,6-Bis((biphenyl-4-yl)-1,3,5-triazine-2-yl)-1,3-benzodiole 485-420-6 - - View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active 4-(4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1-butynyl)-.alpha.,.alpha.-dimethylbenzeneacetic acid 462-560-6 - 2013; 2015 View substance registered dossier
Amino Chemicals Ltd Industrial Estate, A61 MRS3000 Marsa Malta Malta Active 4-(4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1-butynyl)-.alpha.,.alpha.-dimethylbenzeneacetic acid 462-560-6 - - View substance registered dossier
Fine and Performance Chemicals Ltd Skutterskelfe TS15 0JR Hutton Rudby North Yorkshire United Kingdom United Kingdom No longer Valid 4-(4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1-butynyl)-.alpha.,.alpha.-dimethylbenzeneacetic acid 462-560-6 - 2021 View substance registered dossier
TOYO INK EUROPE SPECIALTY CHEMICALS Boulevard Dambourney 76350 Oissel France France Active 4-(4-aminoanilino)-6-[3-(dibutylamino)propylamino]-heteromonocyclic-2-ol 427-670-0 - 2016 View substance registered dossier
- - - - 4-(4-aminoanilino)-6-[3-(dibutylamino)propylamino]-heteromonocyclic-2-ol 427-670-0 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(4-Brom-5-ethyl-tetrahydropyran-2-yl)-phenol 919-822-4 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(4-Brom-5-propyl-tetrahydropyran-2-yl)-phenol 917-991-9 - - View substance registered dossier
All'Chem rue Marceau 03108 MONTLUCON CEDEX France - - 4-(4-chloro-3-nitro-phenyl)-3-methyl-4-oxo-butanoic acid 918-019-6 - - View substance registered dossier
Derivados Químicos S.A. Camino Viejo del Pliego s/n 30820 Alcantarilla Murcia Spain Spain Active 4-(4-chlorophenyl)-1-imidazol-1-ylbutan-2-ol 925-590-5 - - View substance registered dossier
- - - - 4-(4-hydroxyphenyl)cyclohexanone 423-920-8 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(4-trans-propylcylohexyl)phenol 440-740-5 - 2009; 2010; 2013; 2017; 2019 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany - - 4-(4-trans-vinyl-[1,1'-bicyclohexyl]-4'-trans-yl)-1,2-difluorobenzene 430-860-6 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active 4-(5-(5-[1-(4-carboxyphenyl)hexahydro-2,4,6-trioxopyrimidin-5-ylidene]penta-1,3-dienyl)-1,2,3,4-tetrahydro-6-hydroxy-2,4-dioxopyrimidin-1-yl)benzoic acid-triethylamine salt 426-900-7 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 4-(5-ethoxyheptyl)perhydropentalen-2-one 419-880-6 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(5-Ethyl-tetrahydropyran-2-yl)-phenol 921-114-5 - 2020 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide 448-010-8 - 2016 View substance registered dossier
Piramal Healthcare UK Ltd Whalton Road NE61 3YA Morpeth Northumberland United Kingdom United Kingdom Active 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide 448-010-8 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide 448-010-8 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(5-Propyl-tetrahydropyran-2-yl)-phenol 919-949-5 - - View substance registered dossier
Eli Lilly Kinsale Limited Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland Ireland Active 4-(6-(3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile bis sulphate 951-814-6 - - View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active 4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester) 425-880-7 - 2019 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester) 425-880-7 - - View substance registered dossier

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