Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
  • Please be aware that the annual IUCLID format change is coming soon. We will be adapting the Dissemination platform to the new format, which means that as of 15th October 2021 until early 2022 there will be a break in publication of newly submitted registration dossiers. We appreciate your understanding in this matter.
Last updated 13 October 2021. Database contains 23445 unique substances and contains information from 104985 dossiers.
Substance identity
Administrative data
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Substance data
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Details
(1R,4R,5S)-6,6-dimethyl-4-(tribromomethyl)-3-oxabicyclo[3.1.0]hexan-2-one
619-738-5 87305-03-1 Cease Manufacture Intermediate Individual Cease manufacture 19-08-2008 View substance registered dossier
(1R,4S)-2-azabicyclo[2.2.1]hept-5-en-3-one
418-530-1 79200-56-9 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(1R,4S)-6-tert-butoxy-4-(tert-butyldimethylsilyloxy)-6-oxo-1-(2-(thiophen-2-yl)acetamido)hexylboronic acid, (+)-pinanediol ester
812-137-0 1681053-97-3 Active Intermediate Joint Intermediate use only 02-05-2018 View substance registered dossier
(1R,4S,4aR,8aS)-9-(dichloromethylidene)octahydro-1,4-methanonaphthalene-5,8-dione
700-729-0 1369500-14-0 Active Intermediate Joint Intermediate use only 08-12-2020 View substance registered dossier
(1R,4S,4aS,8aR)-9-(dichloromethylene)-1,4,4a,8a-tetrahydro-1,4-methanonaphthalene-5,8-dione
807-377-8 1263184-85-5 Active Intermediate Joint Intermediate use only 21-08-2017 View substance registered dossier
(1R,5R)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene
232-087-8 7785-70-8 Active Full Joint ≥ 10 to < 100 tonnes 18-12-2019 View substance registered dossier
(1R,6S)- 4,7,7-Trimethyl-3-oxabicyclo[4.1.0]hept-4-en-2-one
615-077-1 70174-49-1 Active Intermediate Joint Intermediate use only 16-09-2013 View substance registered dossier
(1R,6S)- 4,7,7-trimethylbicyclo[4.1.0]hept-3-en-2-one
606-984-3 22327-32-8 Active Intermediate Joint Intermediate use only 14-05-2013 View substance registered dossier
(1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylic acid
944-682-6 - Active Intermediate Joint Intermediate use only 22-12-2017 View substance registered dossier
(1R,8S)-2,2,7,7-tetramethyltricyclo[6.2.1.0^{1,6}]undec-5-en-4-one
942-035-2 - Active Intermediate Individual Intermediate use only 04-03-2015 View substance registered dossier
(1RS,2RS,3RS,6RS,8SR)-8-methoxytricyclo[5.2.1.0(2,6)]decane-3-carbaldehyde; (1RS,2RS,4SR,6RS,8SR)-8-methoxytricyclo[5.2.1.0(2,6)]decane-4-carbaldehyde; reaction mass of: (1RS,2RS,3SR,6RS,9SR)-9-methoxytricyclo[5.2.1.0(2,6)]decane-3-carbaldehyde
429-860-9 - Active NONS Joint Tonnage data confidential 24-04-2013 View substance registered dossier
(1RS,2SR,7SR,8SR,Z)-10-ethylidene-3-oxatricyclo[6.2.1.0(2,7)]undecan-4-one; (1RS,2SR,7SR,8SR,Z)-9-ethylidene-3-oxatricyclo[6.2.1.0(2,7)]undecan-4-one; reaction mass of: (1RS,2SR,7SR,8SR,E) 9 and 10-ethylidene-3-oxatricyclo[6.2.1.0(2,7)]undecan-4-one
434-290-9 69486-14-2 Active NONS Joint Tonnage data confidential 11-01-2011 View substance registered dossier
(1S)-(+)-2-AZABICYCLO[2.2.1]HEPT-5-EN-3-ONE
627-840-6 130931-83-8 Active Intermediate Joint Intermediate use only 07-12-2017 View substance registered dossier
(1S)-1,2,3,4-tetrahydro-1-phenylisoquinoline
445-640-5 - Active NONS Individual Tonnage data confidential 25-05-2011 View substance registered dossier
(1S)-1,5-anhydro-2,3,4,6-tetrakis-O-(2,2-dimethylpropanoyl)-1-(3-{[5-(4-fluorophenyl)-2-thienyl]methyl}-4-methylphenyl)-D-glucitol
695-878-0 1283129-18-9 Active Full Joint ≥ 10 to < 100 tonnes 21-11-2019 View substance registered dossier
(1S)-1,5-anhydro-2,3,4,6-tetrakis-O-(2,2-dimethylpropanoyl)-1-(3-{[5-(4-fluorophenyl)-2-thienyl]methyl}-4-methylphenyl)-D-glucitol
695-878-0 1283129-18-9 Active Intermediate Joint Intermediate use only 10-11-2016 View substance registered dossier
(1S)-1-(2-chlorophenyl)-N-methyl-2-oxocyclohexanaminium (2R,3R)-3-carboxy-2,3-dihydroxypropanoate
925-303-3 199468-20-7 Active Intermediate Joint Intermediate use only 09-02-2016 View substance registered dossier
(1S)-1-(3-methoxyphenyl)-N-methylethanamine hydrobromide (1:1)
940-296-7 - Active Full Joint ≥ 1 to < 10 tonnes 11-11-2015 View substance registered dossier
(1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
812-870-6 128196-01-0 Active Intermediate Individual Intermediate use only 26-06-2020 View substance registered dossier
(1S)-1-[3-[(1E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propanol
608-251-3 287930-77-2 Active Full Individual ≥ 10 to < 100 tonnes 03-02-2016 View substance registered dossier
(1S)-1-cyclopropylethanamine; (2R)-2-hydroxy-2-phenyl-acetic acid
946-290-0 - Active Intermediate Joint Intermediate use only 01-10-2020 View substance registered dossier
(1S)-1-NAPHTHYLETHYLAMINE
436-100-1 - Active Intermediate Joint Intermediate use only 20-12-2017 View substance registered dossier
(1S)-1-Phenylethanaminium (2S)-2-(2-fluorobiphenyl-4-yl)propanoate
942-079-2 - No longer Valid Intermediate Individual No longer valid 05-03-2020 View substance registered dossier
(1S)-1-{(2R)-3,4-bis[(2-hexyldecanoyl)oxy]-5-oxo-2,5-dihydrofuran-2-yl}ethane-1,2-diyl bis(2-hexyldecanoate)
430-110-8 183476-82-6 Active Full Joint ≥ 1 tonnes 01-09-2011 View substance registered dossier
(1S)-2,3,4,6-TETRA-O-ACETYL-1,5-ANHYDRO-1-(3-{[5-(4-FLUOROPHENYL)THIOPHEN-2-YL]METHYL}-4-METHYLPHENYL)-D-GLUCITOL
617-901-5 866607-35-4 Active Full Joint ≥ 1 to < 10 tonnes 23-06-2020 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Cheminova A/S Thyborønvej 78 DK-7673 Harboøre Denmark Denmark Cease Manufacture (1R,4R,5S)-6,6-dimethyl-4-(tribromomethyl)-3-oxabicyclo[3.1.0]hexan-2-one 619-738-5 87305-03-1 2014 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (1R,4S)-2-azabicyclo[2.2.1]hept-5-en-3-one 418-530-1 79200-56-9 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (1R,4S)-6-tert-butoxy-4-(tert-butyldimethylsilyloxy)-6-oxo-1-(2-(thiophen-2-yl)acetamido)hexylboronic acid, (+)-pinanediol ester 812-137-0 1681053-97-3 - View substance registered dossier
Syngenta Ltd Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom United Kingdom No longer Valid (1R,4S,4aR,8aS)-9-(dichloromethylidene)octahydro-1,4-methanonaphthalene-5,8-dione 700-729-0 1369500-14-0 2021 View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa - Attiki Greece Greece Active (1R,4S,4aR,8aS)-9-(dichloromethylidene)octahydro-1,4-methanonaphthalene-5,8-dione 700-729-0 1369500-14-0 2019 View substance registered dossier
[Confidential] - - - (1R,4S,4aR,8aS)-9-(dichloromethylidene)octahydro-1,4-methanonaphthalene-5,8-dione 700-729-0 1369500-14-0 - View substance registered dossier
[Confidential] - - - (1R,4S,4aS,8aR)-9-(dichloromethylene)-1,4,4a,8a-tetrahydro-1,4-methanonaphthalene-5,8-dione 807-377-8 1263184-85-5 - View substance registered dossier
Destilerías Muñoz Gálvez, S.A. Avda. Ciudad de Almería, 162 E30010 Murcia Murcia Spain Spain Active (1R,5R)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene 232-087-8 7785-70-8 2019 View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Cease Manufacture (1R,5R)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene 232-087-8 7785-70-8 2017 View substance registered dossier
DESTILACIONES BORDAS CHINCHURRETA, S.A. C/ Acueducto, 4-6 Pol. Ind. Ctra la Isla 41703 Dos Hermanas (Sevilla) Spain Spain Active (1R,5R)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene 232-087-8 7785-70-8 2019 View substance registered dossier
[Confidential] - - - (1R,6S)- 4,7,7-Trimethyl-3-oxabicyclo[4.1.0]hept-4-en-2-one 615-077-1 70174-49-1 - View substance registered dossier
[Confidential] - - - (1R,6S)- 4,7,7-trimethylbicyclo[4.1.0]hept-3-en-2-one 606-984-3 22327-32-8 - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylic acid 944-682-6 - - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (1R,8S)-2,2,7,7-tetramethyltricyclo[6.2.1.0^{1,6}]undec-5-en-4-one 942-035-2 - - View substance registered dossier
FIRMENICH GRASSE SAS OR 2 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (1RS,2RS,3RS,6RS,8SR)-8-methoxytricyclo[5.2.1.0(2,6)]decane-3-carbaldehyde; (1RS,2RS,4SR,6RS,8SR)-8-methoxytricyclo[5.2.1.0(2,6)]decane-4-carbaldehyde; reaction mass of: (1RS,2RS,3SR,6RS,9SR)-9-methoxytricyclo[5.2.1.0(2,6)]decane-3-carbaldehyde 429-860-9 - 2013 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (1RS,2RS,3RS,6RS,8SR)-8-methoxytricyclo[5.2.1.0(2,6)]decane-3-carbaldehyde; (1RS,2RS,4SR,6RS,8SR)-8-methoxytricyclo[5.2.1.0(2,6)]decane-4-carbaldehyde; reaction mass of: (1RS,2RS,3SR,6RS,9SR)-9-methoxytricyclo[5.2.1.0(2,6)]decane-3-carbaldehyde 429-860-9 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (1RS,2SR,7SR,8SR,Z)-10-ethylidene-3-oxatricyclo[6.2.1.0(2,7)]undecan-4-one; (1RS,2SR,7SR,8SR,Z)-9-ethylidene-3-oxatricyclo[6.2.1.0(2,7)]undecan-4-one; reaction mass of: (1RS,2SR,7SR,8SR,E) 9 and 10-ethylidene-3-oxatricyclo[6.2.1.0(2,7)]undecan-4-one 434-290-9 69486-14-2 - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (1RS,2SR,7SR,8SR,Z)-10-ethylidene-3-oxatricyclo[6.2.1.0(2,7)]undecan-4-one; (1RS,2SR,7SR,8SR,Z)-9-ethylidene-3-oxatricyclo[6.2.1.0(2,7)]undecan-4-one; reaction mass of: (1RS,2SR,7SR,8SR,E) 9 and 10-ethylidene-3-oxatricyclo[6.2.1.0(2,7)]undecan-4-one 434-290-9 69486-14-2 2011 View substance registered dossier
SONEAS Chemicals Ltd. Banyaleg Str. 47-59. H-1225 Budapest Hungary Hungary Active (1S)-(+)-2-AZABICYCLO[2.2.1]HEPT-5-EN-3-ONE 627-840-6 130931-83-8 - View substance registered dossier
Astellas Ireland Co.Ltd Damastown Road Damastown Industrial Park NA Mulhuddart Dublin 15 Ireland Ireland Active (1S)-1,2,3,4-tetrahydro-1-phenylisoquinoline 445-640-5 - 2011 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (1S)-1,5-anhydro-2,3,4,6-tetrakis-O-(2,2-dimethylpropanoyl)-1-(3-{[5-(4-fluorophenyl)-2-thienyl]methyl}-4-methylphenyl)-D-glucitol 695-878-0 1283129-18-9 2018; 2019 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (1S)-1,5-anhydro-2,3,4,6-tetrakis-O-(2,2-dimethylpropanoyl)-1-(3-{[5-(4-fluorophenyl)-2-thienyl]methyl}-4-methylphenyl)-D-glucitol 695-878-0 1283129-18-9 - View substance registered dossier
[Confidential] - - - (1S)-1-(2-chlorophenyl)-N-methyl-2-oxocyclohexanaminium (2R,3R)-3-carboxy-2,3-dihydroxypropanoate 925-303-3 199468-20-7 - View substance registered dossier
[Confidential] - - - (1S)-1-(3-methoxyphenyl)-N-methylethanamine hydrobromide (1:1) 940-296-7 - - View substance registered dossier
H. Lundbeck A/S Ottiliavej 7-9 2500 Copenhagen Denmark Denmark Active (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile 812-870-6 128196-01-0 2020 View substance registered dossier
MSD International GmbH Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active (1S)-1-[3-[(1E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propanol 608-251-3 287930-77-2 - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (1S)-1-cyclopropylethanamine; (2R)-2-hydroxy-2-phenyl-acetic acid 946-290-0 - - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active (1S)-1-cyclopropylethanamine; (2R)-2-hydroxy-2-phenyl-acetic acid 946-290-0 - - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (1S)-1-NAPHTHYLETHYLAMINE 436-100-1 - 2017 View substance registered dossier
Aesica Pharmaceuticals Limited Windmill Industrial Estate Shotton Lane NE23 3JL Cramlington Northumberland United Kingdom United Kingdom No longer Valid (1S)-1-Phenylethanaminium (2S)-2-(2-fluorobiphenyl-4-yl)propanoate 942-079-2 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active (1S)-1-{(2R)-3,4-bis[(2-hexyldecanoyl)oxy]-5-oxo-2,5-dihydrofuran-2-yl}ethane-1,2-diyl bis(2-hexyldecanoate) 430-110-8 183476-82-6 - View substance registered dossier
Only representative (No publishable name) - - Active (1S)-1-{(2R)-3,4-bis[(2-hexyldecanoyl)oxy]-5-oxo-2,5-dihydrofuran-2-yl}ethane-1,2-diyl bis(2-hexyldecanoate) 430-110-8 183476-82-6 2011 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (1S)-2,3,4,6-TETRA-O-ACETYL-1,5-ANHYDRO-1-(3-{[5-(4-FLUOROPHENYL)THIOPHEN-2-YL]METHYL}-4-METHYLPHENYL)-D-GLUCITOL 617-901-5 866607-35-4 2019; 2020 View substance registered dossier

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