1,2,3-trichlorobenzene

Hydrolysis

Administrative data

Endpoint:

hydrolysis

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1986

Materials and methods

Principles of method if other than guideline:

Hydrolysis rates were measured under sterile conditions at precisely controlled temperatures and at three pH levels (3, 7 and 11). Chemical concentration (1,2,3-TCB) as a function of incubation time were measured by gas chromatography.

GLP compliance:

not specified

Test material

Test material information

Constituent 1

Reference substance name:

1,2,3-trichlorobenzene

EC Number:

201-757-1

EC Name:

1,2,3-trichlorobenzene

Cas Number:

87-61-6

Molecular formula:

C6H3Cl3

IUPAC Name:

1,2,3-trichlorobenzene

Study design

Buffers:

- pH: 3
- Composition of buffer: 0.005 M potassium hydrogen phthalate and final pH adjustment made with 0.1 HCl
- pH: 7
- Composition of buffer: 0.005 M potassium dihydrogen phoshate and final pH adjustment made with 0.1 NaOH
- pH: 9 and 11
- Composition of buffer: 0.005 M sodium phosphate heptahydrate and final pH adjustment made with 0.1 NaOH

Results and discussion

Any other information on results incl. tables

 Hydrolysis and Analysis Data (1,2,3-trichlorobenzene)

 

pH	Temp [°C]	10³ K1[hr^-1]	T ½ [d]	r ²
3.03	68.0	7.80	3.7	0.755
3.08	70.0	0.79	36.6	0.420
3.07	70.0	1.50	19.2	0.933
3.07	70.0	0.88	32.8	0.691
6.99	68.8	3.28	8.8	0.688
7.13	70.0	0.80	16.1	0.740
7.13	70.0	1.93	15.5	0.867
7.10	70.0	1.90	15.2	0.691
10.70	68.0	3.81	7.6	0.533
9.80	70.0	0.84	34.4	0.626
9.74	70.0	3.0	9.6	0.603