EU-PRODUCT_SAFETY-ART_2

General Product Safety Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of General Product Safety Directive (2001/95/EC), 15 January 2002, amended by Reg 596/2009/EC, 18 July 2009

This list contains a non-exhaustive inventory of substances that fall within the European Union's hazardous substance definitions, as provided on: (1) Table 3 of Annex VI to the CLP Regulation 1272/2008/EC; (2) Annex III of Directive 2000/54/EC (Biological Agents); Candidate List of SVHCs; and REACH Annexes XIV and XVII (Authorisation and Restriction lists). They can be considered hazardous for purposes of the General Product Safety Directive 2001/95/EC.

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Last updated 26 April 2024. Database contains 5503 unique substances/entries.
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Substance Name
EC No.
CAS No.
EU CLP (1272/2008)
EU REACH: Annex XIV
EU REACH: List of SVHC
EU REACH: Annex XVII
EU_BA Directive 2000/54/EC
3-methylheptane
209-660-6
589-81-1
yes
3-methylhexane
209-643-3
589-34-4
yes
3-methylpentane
202-481-4
96-14-0
yes
3-methylpyrazol-5-yl-dimethylcarbamate; monometilan
-
2532-43-6
yes
3-methylpyrazole
215-925-7
1453-58-3
yes
Annex 17 Appendix 6
3-N, N-bis(methoxyethyl)aminoacetanilide
432-530-7
24294-01-7
yes
3-oxoandrost-4-ene-17-β-carboxylic acid
CC14837; SKF 106224
414-990-0
302-97-6
yes
3-pentanol
209-526-7
584-02-1
yes
3-phenyl-7-[4-(tetrahydrofurfuryloxy)phenyl]-1,5-dioxa-s-indacen-2,6-dione
SUMIKARON BRILLIANT RED S-BWF
413-330-9
134724-55-3
yes
3-propanolide;1,3-propiolactone
200-340-1
57-57-8
yes
Annex 17 Appendix 2
3-tridecyloxy-propyl-ammonium 9-octadecenoate
Z-29
418-990-1
778577-53-0
yes
3a,4,7,7a-tetrahydro-4,7-methanoindene
201-052-9
77-73-6
yes
4'-((2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-ene-3-yl)methyl)(1,1'-biphenyl)-2-carbonitrile
4'-((2-BUTYL-4-OXO-1,3-DIAZASPIRO[4,4]NON-1-ÈNE-3-YL)MÉTHYL)BIPHÉNYL-2-CARBONITRILE; 4'-((2-BUTYL-4-OXO-1,3-DIAZASPIRO[4,4]NON-1-ÉN-3-YL)MÉTHYL)BIPHÉNYL-2-CARBONITRILE; 4'-(2-BUTYL-4-OXO-1,3-DIAZASPIRO[4,4]NON-1-ENE-3-YL-METHYL)-BIPHENYL-2-CARBONITRILE; SR 47563
423-500-4
138401-24-8
yes
4'-ethoxy-2-benzimidazoleanilide
LICHTSCHUTZMITTEL 2577
407-600-5
120187-29-3
yes
4'-fluoro-2,2-dimethoxyacetophenone
DMA
407-500-1
21983-80-2
yes
4'-methyldodecane-1-sulfonanilide
435-490-9
17417-32-2
yes
4,4'(4-(4-methoxyphenyl)-1,3,5-triazin-2,4-diyl)bisbenzene-1,3-diol
444-500-0
1440-00-2
yes
4,4', 5,5', 6,6', 7,7'-octachloro-(2,2')biisoindolyl-1,1', 3,3'-tetraone
429-150-9
67887-47-2
yes
4,4',4''-(1-methylpropan-1-yl-3-ylidene)tris(2-cyclohexyl-5-methylphenol)
ARKLS DH-43
407-460-5
111850-25-0
yes
4,4',4''-(ethan-1,1,1-triyl)triphenol
THPE; TRIS(P-HYDROXYPHENYL)ETHANE; TRIS(PARA-HYDROXYPHENYL)ETHANE
405-800-7
27955-94-8
yes
4,4'-(1,3-phenylene-bis(1-methylethylidene))bis-phenol
428-970-4
13595-25-0
yes
4,4'-(1,6-hexamethylenebis(formylimino))bis(2,2,6,6-tetramethyl-1-oxylpiperidine)
427-350-0
182235-14-9
yes
4,4'-(1-Methylpropylidene)bisphenol
201-025-1
77-40-7
yes
4,4'-(1-{4-[1-(4-hydroxyphenyl)-1-methylethyl]phenyl}ethylidene)diphenol
425-600-3
110726-28-8
yes
4,4'-(4-iminocyclohexa-2,5-dienylidenemethylene)dianiline hydrochloride; C.I. Basic Red 9
209-321-2
569-61-9
yes
Annex 17 Appendix 2; Annex 17 Appendix 12
4,4'-(9H-fluoren-9-ylidene)bis(2-chloroaniline)
CAF
407-560-9
107934-68-9
yes
4,4'-(oxy-(bismethylene))-bis-1,3-dioxolane
DIGLYCERINDIFORMAL (DGDF)
423-230-7
56552-15-9
yes
4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene] diphenol; bisphenol AF
216-036-7
1478-61-1
yes
Annex 17 Appendix 6
4,4'-bi-o-toluidine
204-358-0
119-93-7
yes
Annex 17 Appendix 2
4,4'-bis(dimethylamino)-4''-(methylamino)trityl alcohol
209-218-2
561-41-1
yes
yes
4,4'-bis(dimethylamino)benzophenone; Michler's ketone
202-027-5
90-94-8
yes
yes
Annex 17 Appendix 2
4,4'-bis(N-carbamoyl-4-methylbenzenesulfonamide)diphenylmethane
B-TUM
418-770-5
151882-81-4
yes
4,4'-carbonimidoylbis[N, N-dimethylaniline]
207-762-5
492-80-8
yes
4,4'-diamino-2-methylazobenzene
ZP-DK 2115
407-590-2
43151-99-1
yes
4,4'-diaminodiphenylmethane; 4,4'-methylenedianiline
202-974-4
101-77-9
yes
yes
yes
Annex 17 Appendix 2
4,4'-dithiobis(5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-1H-pyrazole-3-carbonitrile)
DISULFURE MB 46307
423-490-1
130755-46-3
yes
4,4'-ethylidenediphenyl dicyanate
AROCY L-10
405-740-1
47073-92-7
yes
4,4'-methylene bis(3-chloro-2,6-di-ethylphenylisocyanate)
420-530-1
177027-34-8
yes
4,4'-methylenebis(2,6-dimethylphenyl cyanate)
AROCY M-10
405-790-4
101657-77-6
yes
4,4'-methylenebis(2-ethylaniline); 4,4'-methylenebis(2-ethylbenzeneamine)
243-420-1
19900-65-3
yes
4,4'-methylenebis(2-isopropyl-6-methylaniline)
LONZACURE M-MIPA
415-150-6
16298-38-7
yes
4,4'-methylenebis(N,N'-dimethylcyclohexanamine)
LUPRAGEN VP 9199 X
412-840-9
13474-64-1
yes
4,4'-methylenebis[N-(4-chlorophenyl)-3-hydroxynaphthalene-2-carboxamide]
430-350-3
192463-88-0
yes
4,4'-methylenedi(cyclohexyl isocyanate); dicyclohexylmethane-4,4'-di-isocyanate
225-863-2
5124-30-1
yes
4,4'-methylenedi-o-toluidine
212-658-8
838-88-0
yes
yes
Annex 17 Appendix 2
4,4'-methylenediphenyl diisocyanate; diphenylmethane-4,4'-diisocyanate
202-966-0
101-68-8
yes
Annex 17
4,4'-oxybis(benzenesulfonylazide)
431-850-4
7456-68-0
yes
4,4'-oxybis(ethylenethio)diphenol
DD-63
404-590-4
90884-29-0
yes
4,4'-oxydi(benzenesulphonohydrazide)
201-286-1
80-51-3
yes
4,4'-Oxydianiline
202-977-0
101-80-4
yes
Annex 17 Appendix 2; Annex 17 Appendix 4
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