EU-PRODUCT_SAFETY-ART_2

General Product Safety Directive - Hazardous Substances

EU. Hazardous Substances for Purposes of General Product Safety Directive (2001/95/EC), 15 January 2002, amended by Reg 596/2009/EC, 18 July 2009

This list contains a non-exhaustive inventory of substances that fall within the European Union's hazardous substance definitions, as provided on: (1) Table 3 of Annex VI to the CLP Regulation 1272/2008/EC; (2) Annex III of Directive 2000/54/EC (Biological Agents); Candidate List of SVHCs; and REACH Annexes XIV and XVII (Authorisation and Restriction lists). They can be considered hazardous for purposes of the General Product Safety Directive 2001/95/EC.

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Last updated 26 April 2024. Database contains 5503 unique substances/entries.
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Substance Name
EC No.
CAS No.
EU CLP (1272/2008)
EU REACH: Annex XIV
EU REACH: List of SVHC
EU REACH: Annex XVII
EU_BA Directive 2000/54/EC
2-{2-[4-(3,6-dimethylheptan-3-yl)phenoxy]ethoxy}ethanol
687-833-9
1119449-38-5
yes
Annex 17
2-{4-(2-ammoniopropylamino)-6-[4-hydroxy-3-(5-methyl-2-methoxy-4-sulfamoylphenylazo)-2-sulfonatonaphth-7-ylamino]-1,3,5-triazin-2-ylamino}-2-aminopropyl formate
SCARLET PE 3948
424-260-3
784157-49-9
yes
2-{4-[4-[4-fluoro-6-(2-(2-vinylsulfonylethoxy)ethylamino)-1,3,5-triazin-2-ylamino]phenylazophenylazo}naphthalene-4,6,8-trisulfonate, trisodium salt
442-230-8
321679-52-1
yes
20-[4-(1,1,3,3-tetramethylbutyl)phenoxy]-3,6,9,12,15,18-hexaoxaicosan-1-ol
219-682-8
2497-59-8
yes
26-(nonylphenoxy)-3,6,9,12,15,18,21,24-octaoxahexacosan-1-ol
247-816-5
26571-11-9
yes
2S-isopropyl-5R-methyl-1R-cyclohexyl (2R, 5S)-5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-[1.3]-oxathiolane-2-carboxylate
425-250-1
147027-10-9
yes
2S-isopropyl-5R-methyl-1R-cyclohexyl 2,2-dihydroxyacetate
GLYOXYLATE DE MENTHYLE HYDRATÉ; MENTHYL GLYOXYLATE HYDRATE
416-810-6
111969-64-3
yes
3',5'-dichloro-2-(2,4-di-tert-pentylphenoxy)-4'-ethyl-2'-hydroxyhexananilide
UC-132
406-840-8
101664-25-9
yes
3',5'-dichloro-4'-ethyl-2'-hydroxypalmitanilide
COUPLER II; UC-136
406-200-8
117827-06-2
yes
3'-(3-acetyl-4-hydroxyphenyl)-1,1-diethylurea
A1354
411-970-3
79881-89-3
yes
3'-trifluoromethylisobutyranilide
BTA-A; FLUTAMIDE BTA-A
406-740-4
1939-27-1
yes
3'5'-anhydro thymidine
425-810-5
38313-48-3
yes
3(or 5)-(4-(N-benzyl-N-ethylamino)-2-methylphenylazo)1,4-dimethyl-1,2,4-triazolium methylsulphate
BASIC RED FC 48215
406-055-0
124584-00-5
yes
3,10-diamino-6,13-dichloro-2-((6-(((4-(1,1-dimethylethyl)phenyl)sulfonyl)amino)-2-naphthalenyl)sulfonyl)-4,11-triphenodioxazinedisulfonic acid, lithium potassium sodium salt
440-770-9
371921-63-0
yes
3,3',5,5'-tetra-tert-butylbiphenyl-2,2'-diol
CA 16-178
407-920-5
6390-69-8
yes
3,3'-bis(dioctyloxyphosphinothioylthio)-N, N'-oxybis(methylene)dipropionamide
Z-4
401-820-5
793710-14-2
yes
3,3'-dichlorobenzidine; 3,3'-dichlorobiphenyl-4,4'-ylenediamine
202-109-0
91-94-1
yes
Annex 17 Appendix 2
3,3'-dicyclohexyl-1,1'-methylenebis(4,1-phenylene)diurea
MDI/CHA
406-370-3
58890-25-8
yes
3,3'-dimethoxybenzidine; o-dianisidine
204-355-4
119-90-4
yes
Annex 17 Appendix 2
3,3'-dimethylbiphenyl-4,4'-diyl diisocyanate
202-112-7
91-97-4
yes
3,3'-dioctadecyl-1,1'-methylene; bis(4,1-phenylene)diurea
MDI/ODA
406-690-3
43136-14-7
yes
3,3'-iminodi(propylamine); dipropylenetriamine
200-261-2
56-18-8
yes
3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctan-1-ol
211-477-1
647-42-7
yes
3,3,4,4-tetrafluoro-4-iodo-1-butene
439-500-2
33831-83-3
yes
3,3,8,8,10,10-hexamethyl-9-[1-(4-oxiranylmethoxy-phenyl)-ethoxy]-1,5-dioxa-9-aza-spiro[5.5]undecane
CGX PR 774
444-420-6
434898-80-3
yes
3,3-dimethylhexane
209-243-9
563-16-6
yes
3,3-dimethylpentane
209-230-8
562-49-2
yes
3,4,3', 4'-tetraphenyl-1,1'-ethandiylbispyrol-2,5-dione
431-500-0
226065-73-2
yes
3,4,5,6-tetrahydrophthalic anhydride
219-374-3
2426-02-0
yes
3,4-dichloro-N-[5-chloro-4-[2-[4-(hexadecyloxy)phenylsulfonyl]butyramido]-2-hydroxyphenyl]benzamide
431-110-0
289708-42-5
yes
3,4-dichloro-N-[5-chloro-4-[2-[4-dodecyloxyphenylsulfonyl]butyramido]-2-hydroxyphenyl]benzamide
431-130-1
327092-50-2
yes
3,4-dichloroaniline
202-448-4
95-76-1
yes
3,4-dihydroxy-5-nitrobenzaldehyde
441-810-8
116313-85-0
yes
3,4-dimethyl-1H-pyrazole
429-130-1
2820-37-3
yes
3,4-dimethylhexane
209-504-7
583-48-2
yes
3,4-dinitrophenol
209-415-3
577-71-9
yes
3,4-dinitrotoluene
210-222-1
610-39-9
yes
Annex 17 Appendix 2
3,4-xylenol
202-439-5
95-65-8
yes
3,5,5-trimethylcyclohex-2-enone; isophorone
201-126-0
78-59-1
yes
3,5-bis((3,5-di-tert-butyl-4-hydroxy)benzyl)-2,4,6-trimethylphenol
IRGANOX 1299
401-110-5
87113-78-8
yes
3,5-bis-(tetradecyloxycarbonyl)benzenesulfinic acid
AF-389
407-990-7
141915-64-2
yes
3,5-dichloro-2,4-difluorobenzoyl fluoride
3,5-DICHLORO-2,4-DIFLUOROBENZOYLFLUORIDE
401-800-6
101513-70-6
yes
3,5-dichloro-2,6-difluoropyrdine-4-amine
220-630-1
2840-00-8
yes
3,5-dichloro-2-fluoro-4-(1,1,2,3,3,3-hexafluoropropoxy)aniline
HPDCFA
441-190-9
121451-05-6
yes
3,5-dichloro-4-(1,1,2,2-tetrafluoroethoxy)aniline
DCATFOB; XRD 473 ANILINE
401-790-3
104147-32-2
yes
3,5-dimethylbenzoyl chloride
DMBC
413-010-9
6613-44-1
yes
3,5-dinitrotoluene
210-566-2
618-85-9
yes
Annex 17 Appendix 2
3,5-xylenol; 3,5-dimethylphenol
203-606-5
108-68-9
yes
3,6,9,12-tetra-azatetradecamethylenediamine; pentacthylenehexamine
223-775-9
4067-16-7
yes
3,6,9-triazaundecamethylenediamine; tetraethylenepentamine
203-986-2
112-57-2
yes
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