Candidate List of substances of very high concern for Authorisation
Candidate List of substances of very high concern for Authorisation
(published in accordance with Article 59(10) of the REACH Regulation)
Candidate List of substances of very high concern for Authorisation
Notes:
- Authentic version: Only the Candidate List published on this website is deemed authentic. Companies may have immediate legal obligations following the inclusion of a substance in the Candidate List on this website including in particular Articles 7, 31 and 33 of the REACH Regulation.
- Numerical identifiers: Each candidate list entry covers both anhydrous and hydrated forms of a substance. The CAS number shown in an entry is typically for the anhydrous form. Hydrated forms of the substance identified by other CAS numbers are still within the scope of the entry.
- Other numerical identifiers: For those entries with "-" in the EC number and CAS number columns, a non-exhaustive inventory of EC and/or CAS Registry numbers describing substances or groups of substances considered to fall within the scope of the Candidate List entry is included, where practicably possible. This information can be accessed through the "Details" button of the selected entry.
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Decision | IUCLID dataset | ||||||
---|---|---|---|---|---|---|---|
271-093-5
|
68515-50-4
|
16-Jun-2014
|
Toxic for reproduction (Article 57c) |
Details | |||
271-084-6
|
68515-42-4
|
20-Jun-2011
|
Toxic for reproduction (Article 57c) |
Details | |||
276-158-1
|
71888-89-6
|
20-Jun-2011
|
Toxic for reproduction (Article 57c) |
Details | |||
with ≥ 0.3% of dihexyl phthalate (EC No. 201-559-5)
show/hide
1,2-Benzenedicarboxylic acid, mixed decyl and hexyl and octyl diesters
EC No.:
272-013-1
| CAS No.:
68648-93-1
|
-
|
-
|
15-Jun-2015
|
Toxic for reproduction (Article 57c) |
Details | ||
202-486-1
|
96-18-4
|
20-Jun-2011
|
Carcinogenic (Article 57a) Toxic for reproduction (Article 57c) |
Details | |||
203-794-9
|
110-71-4
|
18-Jun-2012
|
Toxic for reproduction (Article 57c) |
Details | |||
215-147-8
|
1306-23-6
|
16-Dec-2013
|
Carcinogenic (Article 57a) Specific target organ toxicity after repeated exposure (Article 57(f) - human health) |
Details | |||
show/hide
|
215-146-2
|
1306-19-0
|
20-Jun-2013
|
Carcinogenic (Article 57a) Specific target organ toxicity after repeated exposure (Article 57(f) - human health) |
Details | ||
233-710-6
|
10325-94-7
|
15-Jan-2018
|
Carcinogenic (Article 57a) Mutagenic (Article 57b) Specific target organ toxicity after repeated exposure (Article 57(f) - human health) |
Details | |||
244-168-5
|
21041-95-2
|
15-Jan-2018
|
Carcinogenic (Article 57a) Mutagenic (Article 57b) Specific target organ toxicity after repeated exposure (Article 57(f) - human health) |
Details | |||
208-168-9
|
513-78-0
|
15-Jan-2018
|
Carcinogenic (Article 57a) Mutagenic (Article 57b) Specific target organ toxicity after repeated exposure (Article 57(f) - human health) |
Details | |||
231-152-8
|
7440-43-9
|
20-Jun-2013
|
Carcinogenic (Article 57a) Specific target organ toxicity after repeated exposure (Article 57(f) - human health) |
Details | |||
including cis- and trans- stereo isomeric forms and all possible combinations of the isomers
show/hide
|
-
|
-
|
19-Dec-2012
|
Respiratory sensitising properties (Article 57(f) - human health) |
Details | ||
203-856-5
|
111-30-8
|
08-Jul-2021
|
Respiratory sensitising properties (Article 57(f) - human health) |
Details | |||
EDA
|
203-468-6
|
107-15-3
|
27-Jun-2018
|
Respiratory sensitising properties (Article 57(f) - human health) |
Details | ||
204-650-8
|
123-77-3
|
19-Dec-2012
|
Respiratory sensitising properties (Article 57(f) - human health) |
Details | |||
all possible combinations of the cis- and trans-isomers
show/hide
|
-
|
-
|
19-Dec-2012
|
Respiratory sensitising properties (Article 57(f) - human health) |
Details | ||
trimellitic anhydride; TMA
|
209-008-0
|
552-30-7
|
27-Jun-2018
|
Respiratory sensitising properties (Article 57(f) - human health) |
Details | ||
X4261
|
401-850-9
|
255881-94-8
|
17-Jan-2022
|
PBT (Article 57d) |
Details | ||
and all major diastereoisomers identified
show/hide
|
-
|
-
|
28-Oct-2008
|
PBT (Article 57d) |
Details | ||
200-268-0
|
56-35-9
|
28-Oct-2008
|
PBT (Article 57d) |
Details | |||
204-371-1
|
120-12-7
|
28-Oct-2008
|
PBT (Article 57d) |
Details | |||
232-140-5
|
7789-00-6
|
18-Jun-2010
|
Carcinogenic (Article 57a) Mutagenic (Article 57b) |
Details | |||
213-103-2
|
924-42-5
|
10-Jun-2022
|
Carcinogenic (Article 57a) Mutagenic (Article 57b) |
Details | |||
200-879-2
|
75-56-9
|
19-Dec-2012
|
Carcinogenic (Article 57a) Mutagenic (Article 57b) |
Details | |||
200-589-6
|
64-67-5
|
19-Dec-2012
|
Carcinogenic (Article 57a) Mutagenic (Article 57b) |
Details | |||
215-607-8
|
1333-82-0
|
15-Dec-2010
|
Carcinogenic (Article 57a) Mutagenic (Article 57b) |
Details | |||
201-173-7
|
79-06-1
|
30-Mar-2010
|
Carcinogenic (Article 57a) Mutagenic (Article 57b) |
Details | |||
show/hide
|
-
|
-
|
19-Dec-2012
|
Carcinogenic (Article 57a) Mutagenic (Article 57b) |
Details | ||
-
|
423-400-0
|
59653-74-6
|
18-Jun-2012
|
Mutagenic (Article 57b) |
Details | ||
219-514-3
|
2451-62-9
|
18-Jun-2012
|
Mutagenic (Article 57b) |
Details | |||
show/hide
1-(4-butoxy-1-naphthalenyl)tetrahydrothiophenium 1,1,2,2,3,3,4,4,4-nonafluoro-1-butanesulfonate
EC No.:
468-770-4
| CAS No.:
-
N,N,N-triethylethanaminium 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate
EC No.:
-
| CAS No.:
25628-08-4
|
-
|
-
|
16-Jan-2020
|
Equivalent level of concern having probable serious effects to human health (Article 57(f) - human health) Equivalent level of concern having probable serious effects to the environment (Article 57(f) - environment) |
Details | ||
203-615-4
|
108-78-1
|
17-Jan-2023
|
Equivalent level of concern having probable serious effects to human health (Article 57(f) - human health) Equivalent level of concern having probable serious effects to the environment (Article 57(f) - environment) |
Details | |||
covering any of their individual isomers and combinations thereof
show/hide
potassium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propionate
EC No.:
266-578-3
| CAS No.:
67118-55-2
|
-
|
-
|
16-Jul-2019
|
Equivalent level of concern having probable serious effects to human health (Article 57(f) - human health) Equivalent level of concern having probable serious effects to the environment (Article 57(f) - environment) |
Details | ||
204-661-8
|
123-91-1
|
08-Jul-2021
|
Carcinogenic (Article 57a) Equivalent level of concern having probable serious effects to human health (Article 57(f) - human health) Equivalent level of concern having probable serious effects to the environment (Article 57(f) - environment) |
Details | |||
224-208-8
|
4247-02-3
|
17-Jan-2023
|
Endocrine disrupting properties (Article 57(f) - human health) |
Details | |||
202-318-7
|
94-26-8
|
25-Jun-2020
|
Endocrine disrupting properties (Article 57(f) - human health) |
Details | |||
201-025-1
|
77-40-7
|
08-Jul-2021
|
Endocrine disrupting properties (Article 57(f) - environment) Endocrine disrupting properties (Article 57(f) - human health) |
Details | |||
show/hide
(±)-1,7,7-trimethyl-3-[(4-methylphenyl)methylene]bicyclo[2.2.1]heptan-2-one
EC No.:
253-242-6
| CAS No.:
36861-47-9
(3E)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one
EC No.:
-
| CAS No.:
1782069-81-1
(1R,3E,4S)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one
EC No.:
-
| CAS No.:
95342-41-9
(1S,3E,4R)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one
EC No.:
-
| CAS No.:
852541-30-1
(1R,3Z,4S)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one
EC No.:
-
| CAS No.:
852541-21-0
(1R,4S)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one
EC No.:
-
| CAS No.:
741687-98-9
(1S,3Z,4R)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one
EC No.:
-
| CAS No.:
852541-25-4
|
-
|
-
|
17-Jan-2022
|
Endocrine disrupting properties (Article 57(f) - human health) |
Details | ||
show/hide
|
-
|
-
|
16-Jul-2019
|
Endocrine disrupting properties (Article 57(f) - environment) |
Details | ||
with ≥0.1% w/w 4-heptylphenol, branched and linear (4-HPbl)
show/hide
Reaction product of 1,3,4-thiadiazolidine-2,5-dithione, formaldehyde and phenol, heptyl derivs.
EC No.:
-
| CAS No.:
1471311-26-8
Formaldehyde, reaction products with branched and linear heptylphenol, carbon disulfide and hydrazine
EC No.:
300-298-5
| CAS No.:
93925-00-9
|
-
|
-
|
15-Jan-2018
|
Endocrine disrupting properties (Article 57(f) - environment) |
Details | ||
201-280-9
|
80-46-6
|
12-Jan-2017
|
Endocrine disrupting properties (Article 57(f) - environment) |
Details | |||
202-679-0
|
98-54-4
|
16-Jul-2019
|
Endocrine disrupting properties (Article 57(f) - environment) |
Details | |||
substances with a linear and/or branched alkyl chain with a carbon number of 9 covalently bound in position 4 to phenol, ethoxylated covering UVCB- and well-defined substances, polymers and homologues, which include any of the individual isomers and/or combinations thereof
show/hide
Nonylphenol, branched, ethoxylated
1 - 2.5 moles ethoxylated
EC No.:
500-209-1
| CAS No.:
68412-54-4
44-(nonylphenoxy)-3,6,9,12,15,18,21,24,27,30,33,36,39,42-tetradecaoxatetratetracontanol
EC No.:
260-678-0
| CAS No.:
57321-10-5
4-Nonylphenol, branched, ethoxylated
1 - 2.5 moles ethoxylated
EC No.:
500-315-8
| CAS No.:
127087-87-0
3,6,9,12,15,18,21,24,27-Nonaoxanonacosan-1-ol, 29-(isononylphenoxy)-
EC No.:
-
| CAS No.:
65455-72-3
29-(nonylphenoxy)-3,6,9,12,15,18,21,24,27-nonaoxanonacosanol
EC No.:
248-294-1
| CAS No.:
27177-08-8
26-(nonylphenoxy)-3,6,9,12,15,18,21,24-octaoxahexacosan-1-ol
EC No.:
247-816-5
| CAS No.:
26571-11-9
26-(nonylphenoxy)-3,6,9,12,15,18,21,24-octaoxahexacosan-1-ol;
EC No.:
255-695-5
| CAS No.:
42173-90-0
3,6,9,12-Tetraoxatetradecan-1-ol, 14-(4-nonylphenoxy)-, branched
EC No.:
293-926-1
| CAS No.:
91648-64-5
|
799-990-1
|
-
|
20-Jun-2013
|
Endocrine disrupting properties (Article 57(f) - environment) |
Details | ||
substances with a linear and/or branched alkyl chain with a carbon number of 9 covalently bound in position 4 to phenol, covering also UVCB- and well-defined substances which include any of the individual isomers or a combination thereof
show/hide
|
-
|
-
|
19-Dec-2012
|
Endocrine disrupting properties (Article 57(f) - environment) |
Details | ||
substances with a linear and/or branched alkyl chain with a carbon number of 7 covalently bound predominantly in position 4 to phenol, covering also UVCB- and well-defined substances which include any of the individual isomers or a combination thereof
show/hide
|
-
|
-
|
12-Jan-2017
|
Endocrine disrupting properties (Article 57(f) - environment) |
Details | ||
covering well-defined substances and UVCB substances, polymers and homologues
show/hide
Poly(oxy-1,2-ethanediyl), α-[(1,1,3,3-tetramethylbutyl)phenyl]-ω-hydroxy-
EC No.:
-
| CAS No.:
9036-19-5
20-[4-(1,1,3,3-tetramethylbutyl)phenoxy]-3,6,9,12,15,18-hexaoxaicosan-1-ol
EC No.:
219-682-8
| CAS No.:
2497-59-8
|
-
|
-
|
19-Dec-2012
|
Endocrine disrupting properties (Article 57(f) - environment) |
Details | ||
205-426-2
|
140-66-9
|
19-Dec-2011
|
Endocrine disrupting properties (Article 57(f) - environment) |
Details | |||
3-benzylidene camphor; 3-BC
|
239-139-9
|
15087-24-8
|
15-Jan-2019
|
Endocrine disrupting properties (Article 57(f) - environment) |
Details | ||
with ≥ 0.1% of Michler's ketone (EC No. 202-027-5) or Michler's base (EC No. 202-959-2)
|
229-851-8
|
6786-83-0
|
18-Jun-2012
|
Carcinogenic (Article 57a) |
Details | ||