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EC number: 231-743-0
CAS number: 7718-54-9
Value used for CSA:
Skin irritation / corrosion: irritating
Eye irritation: not irritating
There is some human data for skin irritancy
of nickel chloride, but no skin or eye irritation data from animal
studies on nickel chloride have been found. Human data for nickel
chloride shows skin irritation, and classification is considered
relevant. Skin irritation is also seen with nickel sulphate in similar
is classified as Skin Irrit. 2: H315 in the 1st ATP to the CLP
Regulation with a specific concentration limit of 20%.
Data on eye irritation is available for
nickel sulphate. There is no reason to believe that the eye irritating
potential of nickel chloride will exceed that of nickel sulphate.
Nickel chloride is not classified for eye irritation under CLP.
Regarding respiratory irritation
the available data on nickel chloride do not allow a conclusion for this
The following information is
taken into account for any hazard / risk assessment:
There are some human data for
skin irritancy of nickel chloride, but no skin or eye irritation data
from animalstudies on nickel chloride have been found. Human data for
nickel chloride shows skin irritation, and classification is considered
relevant. This is supported by data using read-across from nickel
sulphate to set the concentration limit since nickel sulphate has been
shown to be irritating to skin in humans at concentrations greater than
20%. A comprehensive summary on this
topic is provided in Appendix B3.
Data regarding eye irritation of Ni acetate
are read-across from Ni sulphate. Ni sulphate has been demonstrated not
to be an eye irritant in experimental animals.
The available data do not allow
any conclusion on respiratory irritation.
Ni chloride is classified as Skin Irrit. 2:
H315 in the 1st ATP to the CLP Regulation
with a specific concentration limit of 20%. Ni
chloride is not classified for eye irritation based on experimental data
in animals with Ni sulphate.A
comprehensive summary on this topic is provided in Appendix
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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