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EC number: 231-743-0 | CAS number: 7718-54-9
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
Freshwater:
From the database of chronic nickel toxicity to freshwater invertebrates, many individual EC10 or NOEC values for different individual species were selected. Chronic data on invertebrates belonging to different taxonomic groups being cladoceran (79% of the data points), amphipods (0.9% of the data), insects (7% of the data), hydrozoans (0.9% of the data), rotifers (5% of the data) and a mollusc (7% of the data). The NOEC/L(E) C10 varied between 1.4 μg/L for Lymnaea stagnalis (Schlekat et al., 2010) and 1,379µg/L for Brachionus calyciflorus (Schlekat et al., 2010). It is noted that the invertebrate data are heavily dominated by data on cladocerans.
The following table indicates those NOEC or EC10 values of high quality that have been carried forward for the HC5-& PNEC derivation:
Key Study
(freshwater invertebrates)
Selected values for the most sensitive endpoints used for derivation of the freshwater HC5
Species
Endpoint
Value (s) (µg/L)
Deleebeecket al., 2008
Daphnia magna
NOEC/EC10
8.8-256
Kunhet al., 1989
Daphnia magna
NOEC
90
Munzinger, 1990
Daphnia magna
NOEC
40
Munzinger, 1994
Daphnia magna
NOEC
80
Keithlyet al., 2004
Ceriodaphnia dubia
NOEC
3.4-5.8
Wirtzet al., 2004
Ceriodaphnia dubia
EC10
2.8-7.6
Deleebeecket al., 2009b
Ceriodaphnia dubia
EC10
7.4-44.2
Nebekeret al., 1984
Clistorina magnifica
NOEC
66
Nebekeret al., 1986
Juga plicifera
NOEC
124
Santiago-Fandino, 1983
Hydra littoralis
NOEC
60
Keithlyet al., 2004
Hyalella azteca
NOEC
29
Deleebeecket al., 2006
Ceriodaphnia quadrangula
NOEC
2.0-12.7
Peracantha truncata
NOEC
2.5-25.8
Daphnia longispina
NOEC
26.6-29.0
Alona affinis
NOEC
25.0
Ceriodaphnia pulchella
NOEC
9.9-28.2
Simocephalus vetulus
NOEC
9.2-28.9
Schlekat et al., 2010
Lymnaea stagnalis
EC10
1.4 -19.5
Brachionus calyciflorus
EC10
498-1379
Chironomus tentans
EC10
404-782
Marine:
From the database of chronic nickel toxicity to marine invertebrates, many NOEC/EC10/LOEC values are reported. EC10 values range from 22.5 μg Ni/L for reproduction of the polychaete, Neanthes arenaceodentata (DeForest and Schlekat, 2013), to 431 μg Ni/L for development of the bivalve,Crassostrea gigas (DeForest and Schlekat, 2013). The table below represents the NOEC, LOEC, or EC10 values of high quality carried forward for derivation of HC5 and aquatic marine PNEC:
Key Study
(marine invertebrates)
Selected values for the most sensitive endpoints used for derivation of the marine HC5
Species
Endpoint
Value (s) (µg/L)
DeForest and Schlekat, 2013
Strongylocentrotus purpuratus
EC10
335
Dendraster excentricus
EC10
191
Huntet al., 2002
Mysidopsis intii
EC10
45.2
Haliotis rufescens
EC10
36.4
Gentileet al., 1982
Mysidopsis bahia
LOEC
141
Mysidopsis bahia
NOEC
61
DeForest and Schlekat, 2013
Mytilius galloprovincialis
EC10
269.7 (geomean)
DeForest and Schlekat, 2013
Neanthes arenaceodentata
EC10
22.5
DeForest and Schlekat, 2013
Crassostrea gigas
EC10
431
Novelliet al., 2003
Paracentrotus lividus
EC10
89
Pagano, 2007
Paracentrotus lividus
EC10
217
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