EU-IMPLANTABLE_MEDICAL_DEVICES-ART_3_ANX_1
EU-IMPLANTABLE_MEDICAL_DEVICES-ART_3_ANX_1
Active Implantable Medical Devices Directive - Hazardous Substances
EU. Hazardous Substances for Purposes of Directive 90/385/EEC on Active Implantable Medical Devices, 20 July 1990, amended by Directive 2007/47/EC, 21 September 2007
This list contains hazardous substances for purposes of Directive 90/385/EEC on active implantable medical devices, particularly as regards Article 3 and Annex I (Essential Requirements). This non-exhaustive database is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list). Please note that Regulation (EU) 2017/745 on medical devices has repealed Directive 90/385/EEC and begun to apply from 26 May 2021. Nevertheless, Article 120 of the Regulation provides for a transitional period allowing medical devices, under specified conditions (e.g., placed on the market prior to 26 May 2021), to continue to comply with the Directive. In accordance with the fourth paragraph of Article 120, this period ends 26 May 2025.
Last updated 03 maj 2024. Database contains 4753 unique substances/entries.
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208-760-7
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540-88-5
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Flam. Liq. 2 |
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1,1-DIMETHYLETHOXY-CARBONYL-METHYLEN-TRIPHENYLPHOSPHORAN; DMY; PHOSPHORANE
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412-880-7
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35000-38-5
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Acute Tox. 3; STOT RE 2; Eye Irrit. 2; Skin Sens. 1 |
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3-BMC
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407-620-4
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33610-13-8
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Resp. Sens. 1; Skin Sens. 1 |
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429-170-8
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134575-17-0
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Acute Tox. 4; STOT RE 2; Eye Dam. 1; Skin Sens. 1 |
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227-637-9
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5915-41-3
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Acute Tox. 4; STOT RE 2 |
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251-637-8
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33693-04-8
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Acute Tox. 4 |
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235-963-8
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13071-79-9
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Acute Tox. 1; Acute Tox. 2 |
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604-715-4
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149979-41-9
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Carc. 2; Repr. 2 |
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203-495-3
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107-49-3
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Acute Tox. 1; Acute Tox. 2 |
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608-879-8
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335104-84-2
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Repr. 2; STOT RE 2; Skin Sens. 1 |
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616-699-6
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79538-32-2
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Acute Tox. 1; Acute Tox. 2 |
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204-178-2
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117-18-0
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Acute Tox. 4; Skin Sens. 1 |
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251-793-7
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34014-18-1
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Acute Tox. 4 |
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601-585-0
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119168-77-3
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Acute Tox. 3; Acute Tox. 4; STOT RE 2; Skin Sens. 1B |
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TEBUCONAZOLE RESP. HWG 1608
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403-640-2
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107534-96-3
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Repr. 2; Acute Tox. 4 |
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211-479-2
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650-51-1
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STOT SE 3 |
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200-927-2
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76-03-9
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Skin Corr. 1A |
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600-363-0
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102851-06-9
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Acute Tox. 4; Skin Irrit. 2 |
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The by-product from the destructive distillation of coal. Almost black semisolid. A complex combination of aromatic hydrocarbons, phenolic compounds, nitrogen bases and thiophene.
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232-361-7
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8007-45-2
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Carc. 1A |
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The deposit removed from crude coal tar storages. Composed primarily of coal tar and carbonaceous particulate matter.
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293-764-1
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91082-50-7
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Carc. 1B |
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The condensation product obtained by cooling, to approximately ambient temperature, the gas evolved in low temperature (less than 700°C (1292°F)) destructive distillation of coal. A black viscous liquid denser than water. Composed primarily of condensed ring aromatic hydrocarbons, phenolic compounds, aromatic nitrogen bases, and their alkyl derivatives.
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266-025-6
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65996-90-9
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Carc. 1A |
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Residues from fractional distillation of low temperature coal tar to remove oils that boil in a range up to approximately 300°C (572°F). Composed primarily of aromatic compounds.
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309-887-1
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101316-85-2
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Carc. 1B |
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The condensation product obtained by cooling, to approximately ambient temperature, the gas evolved in the high temperature (greater than 700°C (1292°F)) destructive distillation of coal. A black viscous liquid denser than water. Composed primarily of a complex mixture of condensed ring aromatic hydrocarbons. May contain minor amounts of phenolic compounds and aromatic nitrogen bases.
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266-024-0
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65996-89-6
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Carc. 1A |
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Solids formed during the coking of bituminous coal to produce crude bituminous coal high temperature tar. Composed primarily of coke and coal particles, highly aromatized compounds and mineral substances.
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309-726-5
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100684-51-3
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Carc. 1B |
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The condensation product obtained by cooling, to approximately ambient temperature, the gas evolved in the high temperature (greater than 700°C (1292°F)) destructive distillation of coal. Composed primarily of a complex mixture of condensed ring aromatic hydrocarbons with a high solid content of coal- and coke-type materials.
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273-615-7
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68990-61-4
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Carc. 1B |
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Coke- and ash-containing solid residues that separate on distillation and thermal treatment of bituminous coal high temperature tar in distillation installations and storage vessels. Consists predominantly of carbon and contains a small quantity of hetero compounds as well as ash components.
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295-535-1
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92062-20-9
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Carc. 1B |
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A tar obtained from low temperature carbonization and low temperature gasification of brown coal. Composed primarily of aliphatic, naphthenic and cyclic aromatic hydrocarbons, heteroaromatic hydrocarbons and cyclic phenols.
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309-886-6
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101316-84-1
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Carc. 1A |
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The distillate from high temperature coal tar having an approximate distillation range of 130°C to 250°C (266°F to 410°F). Composed primarily of naphthalene, alkylnaphthalenes, phenolic compounds, and aromatic nitrogen bases.
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266-016-7
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65996-82-9
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Carc. 1B; Muta. 1B |
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A distillate from low-temperature coal tar. Composed primarily of hydrocarbons, phenolic compounds and aromatic nitrogen bases boiling in the range of approximately 160°C to 340°C (320°F to 644°F).
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309-889-2
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101316-87-4
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Carc. 1B; Muta. 1B |
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The distillate from lignite tar boiling in the range of approximately 80°C to 250°C (176°F to 482°F). Composed primarily of aliphatic and aromatic hydrocarbons and monobasic phenols.
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302-674-4
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94114-40-6
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Carc. 1B; Muta. 1B |
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An oil distilled from brown-coal tar. Composed primarily of aliphatic, naphthenic and one- to three-ring aromatic hydrocarbons, their alkyl derivatives, heteroaromatics and one- and two-ring phenols boiling in the range of approximately 150°C to 360°C (302°F to 680°F).
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309-885-0
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101316-83-0
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Carc. 1A |
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271-020-7
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68513-87-1
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Carc. 1B; Muta. 1B |
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293-767-8
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91082-53-0
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Carc. 1B; Muta. 1B |
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274-560-1
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70321-67-4
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Carc. 1B; Muta. 1B |
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Pyridine bases boiling in the range of approximately 125°C to 160°C (257°F 320°F) obtained by distillation of neutralized acid extract of the base-containing tar fraction obtained by the distillation of bituminous coal tars. Composed chiefly of lutidines and picolines.
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295-548-2
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92062-33-4
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Carc. 1B; Muta. 1B |
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293-766-2
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91082-52-9
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Carc. 1B; Muta. 1B |
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The distillation residue remaining after the distillation of the neutralized, acid-extracted base-containing tar fractions obtained by the distillation of coal tars. It contains chiefly aniline, collidines, quinoline and quinoline derivatives and toluidines.
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295-544-0
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92062-29-8
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Carc. 1B; Muta. 1B |
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The reaction product obtained by neutralizing coal tar base extract oil with an alkaline solution, such as aqueous sodium hydroxide, to obtain the free bases. Composed primarily of such organic bases as acridine, phenanthridine, pyridine, quinoline and their alkyl derivatives.
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266-018-8
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65996-84-1
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Carc. 1B; Muta. 1B |
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The distillation fraction boiling in the range of approximately 181°C to 186°C (356°F to 367°F) from the crude bases obtained from the neutralized, acid-extracted base-containing tar fractions obtained by the distillation of bituminous coal tar. It contains chiefly aniline and collidines.
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295-543-5
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92062-28-7
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Carc. 1B; Muta. 1B |
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The distillation fraction boiling in the range of approximately 180°C to 200°C (356°F to 392°F) from the crude bases obtained by dephenolating and debasing the carbolated oil from the distillation of coal tar. It contains chiefly aniline, collidines, lutidines and toluidines.
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295-541-4
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92062-27-6
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Carc. 1B; Muta. 1B |
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The fraction of tar acids, rich in 2,4- and 2,5-dimethylphenol, recovered by distillation of low-temperature coal tar crude tar acids.
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284-895-5
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84989-06-0
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Carc. 1B; Muta. 1B |
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The residue from the distillation in the range of 235°C to 355°C (481°F to 697°F) of light carbolic oil.
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270-713-1
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68477-23-6
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Carc. 1B; Muta. 1B |
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The fraction of tar acids, recovered by distillation of low-temperature coal tar crude tar acids, having an approximate boiling range of 225°C to 320°C (437°F to 608°F). Composed primarily of polyalkylphenols.
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284-893-4
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84989-05-9
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Carc. 1B; Muta. 1B |
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The fraction of tar acid rich in 3- and 4-methylphenol, recovered by distillation of low-temperature coal tar crude tar acids.
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284-892-9
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84989-04-8
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Carc. 1B; Muta. 1B |
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The fraction of tar acids, rich in 3- and 4-ethylphenol, recovered by distillation of low-temperature coal tar crude tar acids.
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284-891-3
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84989-03-7
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Carc. 1B; Muta. 1B |
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A residue from the distillation of crude phenol from coal. It consists predominantly of phenols having carbon numbers in the range of C8 through C10 with a softening point of 60°C to 80°C (140°F to 176°F).
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306-251-5
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96690-55-0
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Carc. 1B; Muta. 1B |
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A complex combination of organic compounds obtained from brown coal and boiling in the range of approximately 200°C to 230°C (392°F to 446°F). It contains chiefly phenols and pyridine bases.
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295-540-9
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92062-26-5
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Carc. 1B; Muta. 1B |
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272-361-4
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68815-21-4
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Carc. 1B; Muta. 1B |
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The residue from crude coal tar acids after removal of phenol, cresols, xylenols and any higher boiling phenols. A black solid with a melting point approximately 80°C (176°F). Composed primarily of polyalkylphenols, resin gums, and inorganic salts.
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271-418-0
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68555-24-8
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Carc. 1B; Muta. 1B |
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The reaction product obtained by neutralizing coal tar oil alkaline extract with an acidic solution, such as aqueous sulfuric acid, or gaseous carbon dioxide, to obtain the free acids. Composed primarily of tar acids such as phenol, cresols, and xylenols.
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266-019-3
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65996-85-2
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Carc. 1B; Muta. 1B |
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