Ethyl 4-dimethylaminobenzoate

Toxicity to soil microorganisms

Administrative data

Endpoint:

toxicity to soil microorganisms

Type of information:

experimental study planned

Justification for type of information:

According to the Guidance on Information Requirements and Chemical Safety Assessment, Chapter R.7c, substances should be assigned to soil hazard category 3 in case there are no indications that the substance is very toxic to aquatic organisms, and that the substance is not readily biodegradable (unless a soil DT50 < 180 days has been estimated). As the test substance fits this description, it is assigned to soil hazard category 3. Therefore, the approach for screening assessment of the terrestrial hazard in this soil category is to evaluate the risk based on EPM and to conduct a confirmatory long-term soil toxicity study.

As investigating toxicity to soil microorganisms is a standard information requirement for Annex IX substances and this taxon is not covered by the Equilibrium Partitioning Method, a study investigating effects on soil microorganisms to be conducted in accordance with the OECD Test Guideline 216 is proposed.

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 216 (Soil Microorganisms: Nitrogen Transformation Test)

Test material

Test material information

Constituent 1

Reference substance name:

Ethyl 4-dimethylaminobenzoate

EC Number:

233-634-3

EC Name:

Ethyl 4-dimethylaminobenzoate

Cas Number:

10287-53-3

Molecular formula:

C11H15NO2

IUPAC Name:

ethyl 4-(dimethylamino)benzoate