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EC number: 233-634-3
CAS number: 10287-53-3
The toxicity of the test material to fish was investigated in a GLP
study which was conducted in accordance with standardised guideline OECD
203. Due to the low water solubility of the test material in water,
analysis of the test media during the study showed significant declines
in measured test material concentrations and at 24 h had declined to
less than the limit of quantification. Analysis of the
freshly prepared test preparations at 0 and 72 hours showed measured
test concentrations to range from less than the limit of quantification
(0.059 mg/L) to 3.0 mg/L. After 96 hours, 100 % mortality was observed
in the highest test material concentration with sub-lethal effects of
exposure observed at test concentrations above 1.2 mg/L. As
the test material is already definitively classified for chronic aquatic
toxicity at category 2 and a robust conclusion to be reached in the
existing risk assessment long-term test on fish it was not considered
scientifically necessary. In addition the difficulties
maintaining the levels of test material for the duration of the test and
analysing the test material, suggest that the long-term toxicity testing
on fish is unlikely to be technically feasible.
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