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Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
19 July 2016 to 16 March 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to same study
Qualifier:
according to guideline
Guideline:
other: CIPAC MT 187
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
Laser scattering/diffraction
Type of particle tested:
primary particle
Type of distribution:
volumetric distribution
Mass median aerodynamic diameter:
61 µm
Key result
Percentile:
D10
Mean:
24 µm
Remarks on result:
other: no information on standard deviation available
Key result
Percentile:
D50
Mean:
61 µm
Remarks on result:
other: no information on standard deviation available
Key result
Percentile:
D90
Mean:
120 µm
Remarks on result:
other: no information on standard deviation available

Table 1: The overall mean values for the 10, 50 and 90 % quantile results

Parameter

Size (μm)

d(0.1)

24

d(0.5)

61

d(0.9)

120

Conclusions:
Under the conditions of this study, the test material was determined to have d(0.1), d(0.5) and d(0.9) values of 24, 61 and 120 μm, respectively.
Executive summary:

The particle size distribution of the test material was determined in accordance with the standardised guideline CIPAC MT 187 under GLP conditions using particle size apparatus based on laser diffraction.

Under the conditions of the study, the test material was determined to have d(0.1), d(0.5) and d(0.9) values of 24, 61 and 120 μm, respectively.

Description of key information

Under the conditions of the study, the test material was determined to have d(0.1), d(0.5) and d(0.9) values of 24, 61 and 120 μm, respectively.

Additional information

The particle size distribution of the test material was determined in accordance with the standardised guideline CIPAC MT 187 under GLP conditions using particle size apparatus based on laser diffraction. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).

Under the conditions of the study, the test material was determined to have d(0.1), d(0.5) and d(0.9) values of 24, 61 and 120 μm, respectively.