Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 233-634-3
CAS number: 10287-53-3
A study was performed to investigate the potential of the test material
to cause skin irritation in accordance with the standardised guidelines
OECD 404 and EU Method B.4.
Three New Zealand White rabbits were exposed to the test material in a
semi-occlusive manner for 4 hours. The hair was clipped to expose skin
on the dorso-lumbar region and 0.5 g of the test material was applied
under a 2.5 cm² gauze pad, moistened with 0.5 mL of distilled water. The
gauze pads were secured with an elastic adhesive dressing for a
four-hour exposure period. After the four-hour exposure, the wraps were
removed and the test sites were washed with water to remove any residual
test material. The test sites were examined for dermal irritation at
approximately 30 minutes and at 24, 48 and 72 hours following removal of
There were no signs of erythema or oedema during the course of the
study. The mean erythema and oedema scores were 0.0 and 0.0,
respectively. All rabbits scored 0 for both erythema and oedema at each
Under the conditions of this study the test material was determined to
be non-irritating to the skin.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Questo sito web si avvale di cookie affinché possiate usufruire della migliore esperienza sui nostri siti web.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again