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EC number: 201-052-9
CAS number: 77-73-6
The 96 hr EC50 range for the toxicity to
aquatic algae, obtained from a single reliable experimental study, was
22 - >100 mg/L. The estimated EL50 and NOELR from TLM QSAR towards P.
subcapitata are 6.948 mg/L and 1.331 mg /L, respectively. However,
there is a MITI (1997) study for which we do not have all the study
design details which reports an EC50 and NOEC of 27 mg/L and 18 mg/L,
respectively. These values are in much more agreement with those
published by Bentley (1976) and should be given more weight than the
QSAR derived values. Therefore, the MITI values will be used in chemical
et al (1976) tested the toxicity of dicyclopentadiene to three species
of algae. The range of EC50 values reported within the paper was between
22 - >100 mg/L. The study followed a method similar to standard
guidelines but did not include analytical confirmation of the exposure
OECD SIDS identified an Environmental Agency Japan test which showed the
72 hour EC50 to be 27 mg/L and the NOEC to be 18 mg/L. This study was
unavailable for review but is included here as part of a weight of
evidence approach together with the Bentley studies.
QSAR result has also been included as part of the weight of evidence,
which used the ECOSAR program to derive a 96 hour EC50 of 5.1 mg/L and a
ChV of 2.4 mg/L, which corresponds to a NOEC value of 1.7 mg/L
(calculated by ChV ÷v2 as ChV is geometric mean of NOEC and LOEC).
The aquatic toxicity of this substance was
estimated using the Target Lipid Model based on methodologies described
by Mcgrath et al. (2004). The estimated EL50 for this substance is 6.948
mg/L and the NOELR is 1.331 mg/L.
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