Évaluation des substances - plan d'action continu communautaire

If a substance is on this list, it means that a Member State has evaluated or will evaluate it over the coming years. The list is called the Community rolling action plan (CoRAP).

For each substance, the table shows the evaluating Member State, the (planned) year of evaluation and a short description of the concern which led to it being placed on the list.

Documents to do with substance evaluation are also available here. They include: documents justifying selection of the substances, decisions to request more information. Member States' conclusions and Member States' final evaluation reports are included for substances for which evaluation has been finalised.

Notes to the Substance Evaluation table

Where two Members States are indicated, this is a joint evaluation. The first Member State mentioned leads the Evaluation and is the responsible competent authority in the meaning of Article 45(2) of REACH.
The substance public name is used. In most of the cases it is the name as disseminated on the ECHA website.
When the EC Number is not available, the number assigned to substance by ECHA after the inquiry process is used.
When the substances are included in the CoRAP, they have not yet been evaluated and thus the concern is indicative and not exhaustive or conclusive.
Contact details of the evaluating Member States are provided for all the substance included.
Please note that the justification document explains the grounds of the initial concerns that triggered the inclusion of the substance in the CoRAP for further clarification under substance evaluation. The justification document is based on a preliminary screening of the substance and is without prejudice to the outcome of the substance evaluation.

Legend:

Suspected PBT/vPvB: Potentially Persistent, Bioaccumulative and Toxic/very Persistent and very Bioaccumulative.
Suspected PMT/vPvM: Potentially Persistent, Mobile and Toxic/very Persistent and very Mobile.
CMR: generic term for known carcinogenic and/or mutagenic and/or reprotoxic properties (according to CLP harmonised or registrant self-classification or CLP Inventory). The concern can refer to C, M, R or a combination of those.
Suspected CMR: generic term for suspected carcinogenic and/or mutagenic and/or reprotoxic properties (not classified according to CLP harmonised or registrant self-classification). The concern can refer to (suspected) C, M, R or a combination of those.
Sensitiser: generic term for known sensitising properties (according to CLP harmonised or registrant self-classification or CLP Inventory).
Suspected sensitiser: generic term for suspected sensitising properties (not classified according to CLP harmonised or registrant self-classification).
RCR: Risk Characterisation Ratio

Last updated 25 avril 2024. Database contains 402 unique substances/entries.

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Substance Identifier

Evaluating Member State:

Initial grounds for concern:

Status:

Affichage des résultats 301 - 400 parmi 405.

Substance name	EC / List no	CAS no	Year	Evaluating Member State	Initial grounds for concern	Status
Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide	229-782-3	6731-36-8	2014	Germany	Suspected PBT/vPvB	Information requested	Details
decahydronaphthalene	202-046-9	91-17-8	2012	Finland	Suspected PBT/vPvB High (aggregated) tonnage	Ongoing	Details
BISPHENOL A POLYETHYLENE GLYCOL DIETHER DIMETHACRYLATE	609-946-4	41637-38-1		Germany	Suspected PBT/vPvB Exposure of environment	Withdrawn	Details
bis(nonafluorobutyl)phosphinic acid	700-183-3	52299-25-9	2018	Germany	Suspected PBT/vPvB Other hazard based concern Exposure of environment	Concluded	Details
Bis(2-ethylhexyl)amine	203-372-4	106-20-7	2019	Portugal	Suspected PBT/vPvB Exposure of environment	Ongoing	Details
Biphenyl	202-163-5	92-52-4	2013	Portugal	Suspected PBT/vPvB High (aggregated) tonnage	Concluded	Details
Benzene, mono-C11-C13-branched alkyl derivatives	810-801-4	-	2015	Netherlands	Suspected CMR Suspected PBT/vPvB High (aggregated) tonnage	Ongoing	Details
Benzenamine, reaction products with aniline hydrochloride and nitrobenzene	309-912-6	101357-15-7	2019	Germany	Suspected PBT/vPvB	Concluded	Details
ammonium difluoro[1,1,2,2-tetrafluoro-2-(pentafluoroethoxy)ethoxy]acetate	700-323-3	908020-52-0	2017	Germany	Suspected PBT/vPvB Exposure of environment	Concluded	Details
ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoate	700-242-3	62037-80-3	2017	Germany	Suspected PBT/vPvB Exposure of environment	Information requested	Details
a mixture of: triphenylthiophosphate and tertiary butylated phenyl derivatives CD 28-0132; IRGALUBE 232	421-820-9	192268-65-8	2025	Netherlands	Suspected PBT/vPvB	Not started	Details
A mixture of: propan-2-one-O,O'(methoxyvinylsilandiyl)dioxime; propan-2-one-O-(dimethoxyvinylsilyl)oxime; propan-2-one-O,O',O''-(vinylsilantriyl)trioxime WASOX-VMAC2	458-680-3	797751-44-1	2019	Spain	Suspected PBT/vPvB Exposure of environment	Information requested	Details
a mixture of: 4-(2,2,3-trimethylcyclopent-3-en-1-yl)-1-methyl-2-oxabicyclo[2.2.2]octane; 1-(2,2,3-trimethylcyclopent-3-en-1-yl)-5-methyl-6-oxabicyclo[3.2.1]octane; spiro[cyclohex-3-en-1-yl-[(4,5,6,6a-tetrahydro-3,6',6',6'a-tetramethyl)-1,3'(3'aH)-[2H]cyclopenta[b]furan]; spiro[cyclohex-3-en-1-yl-[4,5,6,6a-tetrahydro-4,6',6',6'a-tetramethyl)-1,3'(3'aH)-[2H]cyclopenta[b]]furan] CASSIFFIX	422-040-1	426218-78-2	2016	Spain	Suspected PBT/vPvB Exposure of environment High RCR	Concluded	Details
[3R-(3α,3aβ,7β,8aα)]-1-(2,3,4,7,8,8a-hexahydro-3,6,8,8-tetramethyl-1H-3a,7-methanoazulen-5-yl)ethan-1-one	251-020-3	32388-55-9		Netherlands	Potential endocrine disruptor Suspected PBT/vPvB	Withdrawn	Details
4-tert-butylpyrocatechol	202-653-9	98-29-3	2018	Poland	Suspected Mutagenic Potential endocrine disruptor Suspected PBT/vPvB Sensitiser Exposure of environment Exposure of workers	Concluded	Details
4,4'-methylene bis(dibutyldithiocarbamate)	233-593-1	10254-57-6		Germany	Suspected PBT/vPvB	Withdrawn	Details
4,4'-[(isopropylidene)bis (p-phenyleneoxy)]diphthalic dianhydride	253-781-7	38103-06-9	2013	Germany	Suspected PBT/vPvB High (aggregated) tonnage	Concluded	Details
4,4'-(1,3-phenylene-bis(1-methylethylidene))bisphenol	428-970-4	13595-25-0	2014	Belgium	Suspected PBT/vPvB Other hazard based concern Consumer use Exposure of environment	Concluded	Details
3,3'-dimethylbiphenyl-4,4'-diyl diisocyanate	202-112-7	91-97-4	2013	France	Suspected CMR Suspected PBT/vPvB Sensitiser Consumer use	Concluded	Details
2-Ethoxy-3,3,4,4,5-pentafluoro-2,5-bis[(1,2,2,2-tetrafluoro-1-trifluoromethyl)ethyl] tetrahydrofuran	484-410-9	-	2019	Spain	Suspected PBT/vPvB	Ongoing	Details
2,9-dimethylanthra[2,1,9-def:6,5,10-d'e'f']diisoquinoline-1,3,8,10(2H,9H)-tetrone	226-866-1	5521-31-3		Belgium	Suspected PBT/vPvB	Withdrawn	Details
2,5-di-tert-pentylhydroquinone	201-222-2	79-74-3	2014	Italy	Suspected PBT/vPvB High RCR	Information requested	Details
2,4,6-tri-tert-butylphenol	211-989-5	732-26-3	2017	Belgium	Suspected PBT/vPvB Exposure of environment	Concluded	Details
2,2',6,6'-Tetrabromo-4,4'-isopropylidenediphenol, oligomeric reaction products with Propylene oxide and n-butyl glycidyl ether	926-564-6	-	2016	Germany	Potential endocrine disruptor Suspected PBT/vPvB Exposure of environment	Concluded	Details
10-undecenyl 2-cyano-3,3-diphenylpropenoate	700-604-0	947701-81-7		Finland	Suspected PBT/vPvB Consumer use	Withdrawn	Details
1-hydroxy-4-[[4-[(methylsulphonyl)oxy]phenyl]amino]anthraquinone	216-475-4	1594-08-7	2019	Belgium	Suspected PBT/vPvB	Ongoing	Details
1-(2-hydroxy-5-nonyl(branched)-phenyl)ethanone oxime	627-083-1	244235-47-0	2015	Spain	Suspected PBT/vPvB High (aggregated) tonnage	Concluded	Details
1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylindeno[5,6-c]pyran	214-946-9	1222-05-5	2022	France	Potential endocrine disruptor Suspected PBT/vPvB Consumer use Exposure of environment	Information requested	Details
1,2,3,4-Tetrahydro-6-(1-phenylethyl)naphthalene	400-370-7	6196-98-1	2021	Finland	Suspected PBT/vPvB Exposure of environment	Follow-up	Details
1,1,1,3,5,5,5-heptamethyltrisiloxane	217-496-1	1873-88-7		Norway	Suspected PBT/vPvB	Withdrawn	Details
1,1,1,2,3,3-hexafluoro-2-[1,1,2,3,3,3-hexafluoro-2-[1,1,2,3,3,3-hexafluoro-2-[1,1,2,3,3,3-hexafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propoxy]propoxy]propoxy]-3-(1,2,2,2-tetrafluoroethoxy)propane	-	37486-69-4	2017	Germany	Suspected PBT/vPvB Exposure of environment	Concluded	Details
1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromopropoxy)benzene]	244-617-5	21850-44-2	2017	Germany	Potential endocrine disruptor Suspected PBT/vPvB High (aggregated) tonnage	Concluded	Details
1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromo-2-methylpropoxy)benzene]	306-832-3	97416-84-7	2017	Germany	Potential endocrine disruptor Suspected PBT/vPvB Exposure of environment	Concluded	Details
Titanium dioxide	236-675-5	13463-67-7	2018	France	Carcinogenic Suspected Mutagenic Other hazard based concern	Information requested	Details
Phenol	203-632-7	108-95-2	2015	Denmark	Suspected Mutagenic Other hazard based concern Consumer use Exposure of workers High (aggregated) tonnage High RCR	Concluded	Details
Oxirane, mono[(C12-14-alkyloxy)methyl] derivs.	271-846-8	68609-97-2		Ireland	Suspected Mutagenic Sensitiser Other hazard based concern Consumer use Exposure of workers High (aggregated) tonnage	Withdrawn	Details
N,N-diethylhydroxylamine	223-055-4	3710-84-7	2019	Sweden	Suspected Carcinogenic Suspected Mutagenic	Concluded	Details
4,4'-bis(diethylamino)benzophenone	202-025-4	90-93-7	2021	Netherlands	Suspected Carcinogenic Suspected Mutagenic	Concluded	Details
2,2-dimethylpropan-1-ol, tribromo derivative; 3-bromo-2,2-bis(bromomethyl)propan-1-ol	253-057-0	36483-57-5		Denmark	Suspected Carcinogenic Suspected Mutagenic	Withdrawn	Details
Tin sulphate	231-302-2	7488-55-3	2016	France	Suspected CMR Sensitiser Consumer use High (aggregated) tonnage	Concluded	Details
Succinic anhydride	203-570-0	108-30-5	2013	Austria	Suspected CMR Sensitiser High (aggregated) tonnage High RCR	Concluded	Details
Methyl salicylate	204-317-7	119-36-8	2015	France	Suspected CMR Consumer use High (aggregated) tonnage	Concluded	Details
Hexamethyldisiloxane	203-492-7	107-46-0	2013	Norway	Suspected CMR Consumer use High (aggregated) tonnage	Information requested	Details
Hexafluoropropene	204-127-4	116-15-4	2015	Italy	Suspected CMR High (aggregated) tonnage	Concluded	Details
Diundecyl phthalate, branched and linear	287-401-6	85507-79-5	2014	Denmark	Suspected CMR High (aggregated) tonnage Other exposure/risk based concern	Concluded	Details
Butyl acrylate	205-480-7	141-32-2	2013	Sweden	Suspected CMR High (aggregated) tonnage Other exposure/risk based concern	Concluded	Details
Aluminium chloride basic	215-477-2	1327-41-9	2015	France	Suspected CMR High (aggregated) tonnage	Follow-up	Details
Aluminium chloride	231-208-1	7446-70-0	2015	France	Suspected CMR Exposure of workers High (aggregated) tonnage High RCR	Follow-up	Details
7-oxabicyclo[4.1.0]hept-3-ylmethyl 7-oxabicyclo [4.1.0]heptane-3-carboxylate	219-207-4	2386-87-0	2013	Ireland	Suspected CMR Sensitiser Exposure of workers High RCR	Concluded	Details
4-hydroxybenzoic acid	202-804-9	99-96-7	2014	Czech Republic	Suspected CMR Potential endocrine disruptor Consumer use High (aggregated) tonnage	Concluded	Details
4,4'-sulfonyldiphenol	201-250-5	80-09-1	2014	Belgium	Suspected CMR Potential endocrine disruptor High (aggregated) tonnage	Concluded	Details
1,2-benzenedicarboxylic acid, di-C9-11-branched and linear alkyl esters	271-085-1	68515-43-5	2014	Denmark	Suspected CMR High (aggregated) tonnage Other exposure/risk based concern	Concluded	Details
1,2-benzenedicarboxylic acid, di-C11-14-branched alkyl es-ters, C13-rich	271-089-3	68515-47-9	2014	Denmark	Suspected CMR High (aggregated) tonnage Other exposure/risk based concern	Concluded	Details
1,2-benzenedicarboxylic acid, di-C10-12-branched alkyl esters	700-989-5	-	2014	Denmark	Suspected CMR High (aggregated) tonnage Other exposure/risk based concern	Concluded	Details
1,2-Benzenedicarboxylic acid, benzyl isononyl alkyl esters	701-339-3	-	2014	Denmark	Suspected CMR High (aggregated) tonnage Other exposure/risk based concern	Concluded	Details
Maleic anhydride	203-571-6	108-31-6	2013	Austria	Sensitiser High (aggregated) tonnage High RCR	Concluded	Details
Fatty acids C18 unsat, reaction products with Pentaethylenehexamine	629-732-4	1224966-13-5	2015	Lithuania	Sensitiser Exposure of sensitive populations Exposure of workers	Concluded	Details
bis(pentane-2,4-dionato)calcium	243-001-3	19372-44-2	2015	Germany	Sensitiser Other hazard based concern Exposure of workers High (aggregated) tonnage	Concluded	Details
Bis(4-hydroxy-N-methylanilinium) sulphate	200-237-1	55-55-0	2020	Italy	Mutagenic Sensitiser Other hazard based concern	Concluded	Details
Amylase, α-	232-565-6	9000-90-2	2015	United Kingdom	Sensitiser Consumer use Exposure of workers	Concluded	Details
5-amino-o-cresol	220-618-6	2835-95-2	2020	Italy	Mutagenic Sensitiser Other hazard based concern	Information requested	Details
4-aminophenol	204-616-2	123-30-8	2020	Italy	Mutagenic Sensitiser Other hazard based concern	Concluded	Details
3-aminophenol	209-711-2	591-27-5	2020	Italy	Mutagenic Sensitiser Other hazard based concern	Information requested	Details
Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide	278-355-8	75980-60-8		Sweden	Reprotoxic Potential endocrine disruptor	Withdrawn	Details
Dimethoxydimethylsilane	214-189-4	1112-39-6		Belgium	Reprotoxic Other hazard based concern Exposure of workers	Withdrawn	Details
Cyclohexylamine	203-629-0	108-91-8	2016	Belgium	Reprotoxic Exposure of environment High (aggregated) tonnage	Concluded	Details
4-methylanisole	203-253-7	104-93-8	2021	Ireland	Reprotoxic	Concluded	Details
3,5-dimethylpyrazole	200-657-5	67-51-6		Spain	Reprotoxic High RCR	Withdrawn	Details
Ziram	205-288-3	137-30-4	2012	Denmark	Potential endocrine disruptor High RCR	Information requested	Details
Tris[2-chloro-1-(chloromethyl)ethyl] phosphate	237-159-2	13674-87-8		Germany	Potential endocrine disruptor	Withdrawn	Details
Resorcinol	203-585-2	108-46-3	2019	France	Potential endocrine disruptor High (aggregated) tonnage	Information requested	Details
Reaction mass of p-t-butylphenyldiphenyl phosphate and bis(p-t-butylphenyl) phenyl phosphate	939-505-4	-	2023	France	Potential endocrine disruptor Exposure of environment	Ongoing	Details
Reaction mass of 2,2'-[methylenebis(2,1-phenyleneoxymethylene)]bis(oxirane) and 2,2'-[methylenebis(4,1-phenyleneoxymethylene)]bis(oxirane) and 2-({2-[4-(oxiran-2-ylmethoxy)benzyl]phenoxy}methyl)oxirane	701-263-0	-	2020	Denmark	Potential endocrine disruptor	Concluded	Details
Phenol, dodecyl-, branched	310-154-3	121158-58-5	2018	Germany	Potential endocrine disruptor	Concluded	Details
Nonylphenol, branched, ethoxylated 1 - 2.5 moles ethoxylated	500-209-1	68412-54-4	2016	United Kingdom	Potential endocrine disruptor Other hazard based concern High (aggregated) tonnage	Concluded	Details
Ethyl 4-hydroxybenzoate	204-399-4	120-47-8		Germany	Potential endocrine disruptor	Withdrawn	Details
Dapsone	201-248-4	80-08-0	2016	Germany	Potential endocrine disruptor	Concluded	Details
Chloromethane	200-817-4	74-87-3	2012	Italy	CMR Potential endocrine disruptor High RCR	Concluded	Details
Carbon disulphide	200-843-6	75-15-0	2013	France	CMR Potential endocrine disruptor Exposure of environment Exposure of workers High (aggregated) tonnage	Concluded	Details
Benzyl salicylate	204-262-9	118-58-1		Germany	Potential endocrine disruptor	Withdrawn	Details
Benzotriazole	202-394-1	95-14-7	2016	Germany	Potential endocrine disruptor Exposure of environment	Concluded	Details
4-tert-butylphenol	202-679-0	98-54-4	2014	Germany	Potential endocrine disruptor High (aggregated) tonnage	Concluded	Details
4-(4-isopropoxyphenylsulfonyl)phenol D-8; DD-8	405-520-5	95235-30-6	2025	Belgium	Potential endocrine disruptor Other exposure/risk based concern	Not started	Details
2-ethylhexyl salicylate	204-263-4	118-60-5		Germany	Potential endocrine disruptor	Withdrawn	Details
2-ethylhexyl 10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-oxoethyl]thio]-4-octyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate	248-227-6	27107-89-7		Netherlands	Potential endocrine disruptor	Withdrawn	Details
2,2'-dimethyl-4,4'-methylenebis(cyclohexylamine)	229-962-1	6864-37-5	2015	Germany	Potential endocrine disruptor	Concluded	Details
1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one EC No. 216-133-4 and EC No. 244-240-6 show/hide 1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one EC / List no: 244-240-6 \| CAS no: 21145-77-7 1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one EC / List no: 216-133-4 \| CAS no: 1506-02-1	-	-	2020	Germany	Potential endocrine disruptor High (aggregated) tonnage	Information requested	Details
1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione, zinc salt	262-872-0	61617-00-3	2018	Germany	Potential endocrine disruptor Exposure of environment	Concluded	Details
1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione	258-904-8	53988-10-6	2018	Germany	Potential endocrine disruptor Exposure of environment	Concluded	Details
(3E)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one	701-394-3	1782069-81-1	2020	Germany	Potential endocrine disruptor	Concluded	Details
methylethylketone peroxide trimer	429-320-2	24748-23-0	2019	Netherlands	PBT/vPvB	Information requested	Details
Silicon dioxide	231-545-4	7631-86-9	2012	Netherlands	Other hazard based concern Other exposure/risk based concern	Concluded	Details
methacrylamide	201-202-3	79-39-0	2016	Sweden	Other hazard based concern Exposure of workers	Concluded	Details
2-(phenylmethoxy)naphthalene BENZYL-2-NAPHTHYLETHER; BETA-NAPHTHYLBENZYLETHER (BON); BNE; BON; NIPAFAX BNE; SENSLON-50; ZO-1	405-490-3	613-62-7	2012	Czech Republic	Other hazard based concern High (aggregated) tonnage	Concluded	Details
Naphthalene	202-049-5	91-20-3	2016	United Kingdom	Exposure of workers High (aggregated) tonnage High RCR Other exposure/risk based concern	Concluded	Details
Dimethyl disulphide	210-871-0	624-92-0	2014	Germany	Exposure of environment High (aggregated) tonnage Other exposure/risk based concern	Concluded	Details
Buta-1,3-diene	203-450-8	106-99-0	2014	Germany	CMR Other exposure/risk based concern	Concluded	Details
Beryllium	231-150-7	7440-41-7	2013	Germany	Other exposure/risk based concern	Concluded	Details
2,3-epoxypropyl o-tolyl ether	218-645-3	2210-79-9	2016	Denmark	Mutagenic	Concluded	Details
1,3-diphenylguanidine	203-002-1	102-06-7	2012	France	CMR High (aggregated) tonnage High RCR	Concluded	Details

Affichage des résultats 301 - 400 parmi 405.

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