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As of end June 2022 we have processed and published all dossiers that had been pending since 14 October 2021. While daily processing has resumed there remains a processing queue. New submissions will be at the back of the processing queue, and may be slightly delayed before publication. We appreciate your understanding in this matter.

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Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
(S)-4-amino-5-[(2-(1H-imidazol-4-yl)ethyl)amino]-5-oxopentanoic acid
L-GLUTAMYL-HISTAMINE
421-900-3 169283-81-2 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
(S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
CAMPTOTHECIN
444-280-6 7689-03-4 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(S)-4-methyloxazolidine-2,5-dione
218-750-4 2224-52-4 Active Intermediate Joint Intermediate use only 13-04-2018 View substance registered dossier
(S)-5'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-ium benzenesulfonate
848-452-5 2097130-30-6 Active Full Joint ≥ 1 to < 10 tonnes 28-02-2021 View substance registered dossier
(S)-5-[2-(acetyloxy)propanamido]-2,4,6-triiodo-1,3-di(chloroformyl)benzene
LACTOFTALURO
410-940-7 60166-91-8 Active Intermediate Joint Intermediate use only 20-05-2022 View substance registered dossier
(S)-5-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1H-pyrazole-3-carboxamide
941-760-1 1297537-33-7 Active Intermediate Individual Intermediate use only 04-01-2018 View substance registered dossier
(S)-5-chloro-4-methyl-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole dihydrochloride
948-271-2 - Active Intermediate Joint Intermediate use only 09-07-2018 View substance registered dossier
(S)-5-fluoro-3-methylisobenzofuran-1(3H)-one
943-180-4 1803573-19-4 Active Intermediate Joint Intermediate use only 11-09-2019 View substance registered dossier
(S)-5-Methoxy-2-propionamidotetralin
607-376-0 244239-67-6 Active Intermediate Joint Intermediate use only 02-03-2018 View substance registered dossier
(S)-5-tert-butoxy-3-(tert-butyldimethylsilyloxy)-5-oxopentylboronic acid (+)-pinanediol ester
811-219-3 1681053-95-1 Active Intermediate Individual Intermediate use only 28-02-2018 View substance registered dossier
(S)-7-[[2-O-6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one
236-216-9 13241-33-3 Active Full Joint ≥ 10 to < 100 tonnes 13-11-2017 View substance registered dossier
(S)-7-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-.beta.-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one glucopyranosyl ether
471-940-0 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(S)-7-hydroxy-3,7-dimethyloctanal
829-246-4 34212-53-8 Active Full Joint ≥ 1 to < 10 tonnes 22-03-2019 View substance registered dossier
(S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle
439-220-0 - Active Intermediate Joint Intermediate use only 08-07-2015 View substance registered dossier
(S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle
439-220-0 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(S)-alpha-hydroxy-benzeneacetic acid compd. With (R)-N-methyl-gamma-(2-methylphenoxy)benzenepropanamine (1:1)
617-437-3 83113-55-7 Active Intermediate Joint Intermediate use only 20-11-2020 View substance registered dossier
(S)-azetidine-2-carboxylic acid 4-cyanobenzylamide hydrochloride
433-010-2 2135910-74-4 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate
445-820-3 - Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
(S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate
445-820-3 - Active Intermediate Individual Intermediate use only 19-06-2018 View substance registered dossier
(S)-methyl 5-(4-(benzyloxy)phenyl)-3,4-dihydro-2H-pyrrole-2-carboxylate
815-198-1 934240-38-7 Cease Manufacture Intermediate Joint Cease manufacture 14-03-2018 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
- - - - (S)-4-amino-5-[(2-(1H-imidazol-4-yl)ethyl)amino]-5-oxopentanoic acid 421-900-3 169283-81-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority. - - Active (S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione 444-280-6 7689-03-4 - View substance registered dossier
PMC ISOCHEM 32 rue Lavoisier 91710 VERT LE PETIT France France Active (S)-4-methyloxazolidine-2,5-dione 218-750-4 2224-52-4 - View substance registered dossier
Zoetis Belgium S.A. Rue Laid Burniat, 1 1348 Louvain-La-Neuve Belgium Belgium Active (S)-5'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-ium benzenesulfonate 848-452-5 2097130-30-6 - View substance registered dossier
bracco imaging Via Folli 50 20134 milan Italy Italy Active (S)-5-[2-(acetyloxy)propanamido]-2,4,6-triiodo-1,3-di(chloroformyl)benzene 410-940-7 60166-91-8 2022 View substance registered dossier
Fermion Oy Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland Finland Active (S)-5-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1H-pyrazole-3-carboxamide 941-760-1 1297537-33-7 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (S)-5-chloro-4-methyl-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole dihydrochloride 948-271-2 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (S)-5-fluoro-3-methylisobenzofuran-1(3H)-one 943-180-4 1803573-19-4 2019 View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (S)-5-Methoxy-2-propionamidotetralin 607-376-0 244239-67-6 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (S)-5-tert-butoxy-3-(tert-butyldimethylsilyloxy)-5-oxopentylboronic acid (+)-pinanediol ester 811-219-3 1681053-95-1 - View substance registered dossier
[Confidential] - - - (S)-7-[[2-O-6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one 236-216-9 13241-33-3 - View substance registered dossier
- - - - (S)-7-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-.beta.-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one glucopyranosyl ether 471-940-0 - - View substance registered dossier
TAKASAGO TEPL-OR(1) 12 rue Torricelli 75017 Paris France France Active (S)-7-hydroxy-3,7-dimethyloctanal 829-246-4 34212-53-8 - View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active (S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle 439-220-0 - - View substance registered dossier
- - - - (S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle 439-220-0 - - View substance registered dossier
Eli Lilly Kinsale Limited Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland Ireland Active (S)-alpha-hydroxy-benzeneacetic acid compd. With (R)-N-methyl-gamma-(2-methylphenoxy)benzenepropanamine (1:1) 617-437-3 83113-55-7 - View substance registered dossier
Sicor - Società Italiana Corticosteroidi S.r.l. Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy Italy Active (S)-alpha-hydroxy-benzeneacetic acid compd. With (R)-N-methyl-gamma-(2-methylphenoxy)benzenepropanamine (1:1) 617-437-3 83113-55-7 - View substance registered dossier
AstraZeneca B313:5 AZ GlobalSHE- Chem.Reg. SE-15185 Södertälje Sweden Sweden Cease Manufacture (S)-azetidine-2-carboxylic acid 4-cyanobenzylamide hydrochloride 433-010-2 2135910-74-4 2012 View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid (S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate 445-820-3 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate 445-820-3 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active (S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate 445-820-3 - - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate 445-820-3 - - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Cease Manufacture (S)-methyl 5-(4-(benzyloxy)phenyl)-3,4-dihydro-2H-pyrrole-2-carboxylate 815-198-1 934240-38-7 2022 View substance registered dossier

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