EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1
EU-IN_VITRO_MEDICAL_DEVICES-ART_3_ANX_1
In Vitro Diagnostic Medical Devices Directive - Hazardous Substances
EU. Hazardous Substances for Purposes of Article 3 & Annex I (Essential Requirements), Directive 98/79/EC on In Vitro Diagnostic Medical Devices, 7 December 1998
This list contains a non-exhaustive inventory of hazardous substances for purposes of essential requirements (Article 3 and Annex I) for general safety, design, manufacture and hazard communication of in vitro diagnostic medical devices. It is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list). Note that Regulation 2017/746/EU on in vitro diagnostic medical devices was published in the EU Official Journal on 5 May 2017. With few exceptions specified in Articles 112 and 113 of this Regulation, Directive 98/79/EC is repealed, and the rules pursuant to 2017/746/EU apply, from 26 May 2022.
Last updated 26 April 2024. Database contains 4821 unique substances/entries.
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223-498-3
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3926-62-3
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Acute Tox. 3; Skin Irrit. 2 |
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219-007-7
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2312-76-7
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Acute Tox. 3; STOT RE 2 |
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233-267-9
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10102-18-8
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Acute Tox. 2; Acute Tox. 3; Skin Sens. 1 |
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430-090-0
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205764-96-1
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Eye Dam. 1; Skin Sens. 1 |
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205-025-2
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131-52-2
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Carc. 2; Acute Tox. 2; Acute Tox. 3; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2 |
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287-500-4
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85536-19-2
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Carc. 1B; Muta. 1B |
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287-498-5
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85536-17-0
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Carc. 1B; Muta. 1B |
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287-502-5
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85536-20-5
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Carc. 1B; Muta. 1B |
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The distillate from either high temperature coal tar, coke oven light oil, or coal tar oil alkaline extract residue having an approximate distillation range of 130°C to 210°C (266°F to 410°F) Composed primarily of indene and other polycyclic ring systems containing a single aromatic ring. May contain phenolic compounds and aromatic nitrogen bases.
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266-013-0
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65996-79-4
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Carc. 1B; Muta. 1B |
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A complex combination of hydrocarbons obtained from the distillation of crude oil or natural gasoline. It consists predominantly of saturated hydrocarbons having carbon numbers predominantly in the range of C11 through C16 and boiling in the range of approximately 190°C to 290°C (374°F to 554°F).
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265-200-4
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64742-96-7
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Asp. Tox. 1 |
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A complex combination of hydrocarbons obtained from distillation of aromatic streams. It consists predominantly of aromatic hydrocarbons having carbon numbers predominantly in the range of C9 through C16 and boiling in the range of approximately 165°C to 290°C (330°F to 554°F).
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265-198-5
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64742-94-5
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Asp. Tox. 1 |
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A complex combination of hydrocarbons obtained by the distillation of hydrocracked petroleum distillate. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C9 through C16 and boiling in the range of approximately 235°C to 290°C (455°F to 554°F).
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309-881-9
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101316-80-7
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Asp. Tox. 1 |
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A complex combination of hydrocarbons obtained by the catalytic hydrodesulfurization of a petroleum fraction. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C10 through C13 and boiling in the range of approximately 180°C to 240°C (356°F to 464°F).
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309-882-4
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101316-81-8
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Asp. Tox. 1 |
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A complex combination of hydrocarbons obtained by the catalytic hydrodesulfurization of a petroleum fraction. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C10 through C13 and boiling in the range of approximately 175°C to 220°C (347°F to 428°F).
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309-884-5
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101316-82-9
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Asp. Tox. 1 |
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A complex combination of hydrocarbons obtained by treating a petroleum fraction with hydrogen in the presence of a catalyst. It consists predominantly of cycloparaffinic hydrocarbons having carbon numbers predominantly in the range of C6 through C7 and boiling in the range of approximately 73°C to 85°C (163°F to 185°F).
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295-529-9
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92062-15-2
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Carc. 1B; Muta. 1B; Asp. Tox. 1 |
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A complex combination of hydrocarbons obtained from the distillation of crude oil or natural gasoline. It consists predominantly of saturated hydrocarbons having carbon numbers predominantly in the range of C5 through C10 and boiling in the range of approximately 35°C to 160°C (95°F to 320°F).
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265-192-2
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64742-89-8
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Carc. 1B; Muta. 1B; Asp. Tox. 1 |
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A complex combination of hydrocarbons obtained by treating a petroleum fraction with hydrogen in the presence of a catalyst. It consists predominantly of aromatic hydrocarbons having carbon numbers predominantly in the range of C8 through C10 and boiling in the range of approximately 135°C to 210°C(275°F to 410°F).
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270-988-8
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68512-78-7
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Carc. 1B; Muta. 1B; Asp. Tox. 1 |
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A complex combination of hydrocarbons obtained from distillation of aromatic streams. It consists predominantly of aromatic hydrocarbons having carbon numbers predominantly in the range of C8 through C10 and boiling in the range of approximately 135°C to 210°C (275°F to 410°F).
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265-199-0
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64742-95-6
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Carc. 1B; Muta. 1B; Asp. Tox. 1 |
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A complex combination of hydrocarbons obtained from the distillation of crude oil or natural gasoline. It consists predominantly of saturated hydrocarbons having carbon numbers predominantly in the range of C9 through C12 and boiling in the range of approximately 140°C to 220°C (284°F to 428°F).
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265-191-7
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64742-88-7
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STOT RE 1; Asp. Tox. 1 |
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604-636-5
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148477-71-8
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Carc. 1B; Repr. 2; STOT RE 2; Skin Sens. 1B |
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606-523-6
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203313-25-1
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Repr. 2; STOT SE 3; Eye Irrit. 2; Skin Sens. 1A |
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601-505-4
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118134-30-8
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Repr. 2; Acute Tox. 4; STOT RE 2; Skin Irrit. 2; Skin Sens. 1 |
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F Fungi |
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V Viruses: Member States are to ensure that all viruses which have already been isolated in humains and which have not been assessed and allocated in this Annex are classified in group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans. |
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B Bacteria and similar species |
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A colorless, refined petroleum distillate that is free from rancid or objectionable odors and that boils in a range of approximately 148.8°C to 204.4°C (300°F to 400°F).
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232-489-3
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8052-41-3
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Carc. 1B; Muta. 1B; STOT RE 1; Asp. Tox. 1 |
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-
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B Bacteria and similar species |
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B Bacteria and similar species |
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B Bacteria and similar species |
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B Bacteria and similar species |
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B Bacteria and similar species |
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P Parasites |
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P Parasites |
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427-930-3
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250639-69-1
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Skin Sens. 1 |
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232-142-6
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7789-06-2
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Carc. 1B; Acute Tox. 4 |
yes |
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234-239-9
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11005-63-3
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Acute Tox. 3; STOT RE 2 |
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269-710-8
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68310-42-9
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Acute Tox. 2 |
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269-439-5
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68239-26-9
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Acute Tox. 2 |
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200-319-7
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57-24-9
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Acute Tox. 1; Acute Tox. 2 |
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202-851-5
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100-42-5
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Flam. Liq. 3; Repr. 2; Acute Tox. 4; STOT RE 1; Skin Irrit. 2; Eye Irrit. 2 |
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202-476-7
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96-09-3
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Carc. 1B; Acute Tox. 4; Eye Irrit. 2 |
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STYRENE SULPHONYL CHLORIDE
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404-770-2
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2633-67-2
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Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1 |
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232-752-2
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9014-01-1
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STOT SE 3; Skin Irrit. 2; Eye Dam. 1; Resp. Sens. 1 |
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203-570-0
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108-30-5
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Acute Tox. 4; Skin Corr. 1; Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1 |
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619-394-6
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99105-77-8
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Repr. 2; STOT RE 2; Skin Sens. 1A |
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202-388-9
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95-06-7
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Carc. 1B; Acute Tox. 4 |
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222-995-2
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3689-24-5
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Acute Tox. 1; Acute Tox. 2 |
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807-366-8
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946578-00-3
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Acute Tox. 4 |
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231-722-6
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7704-34-9
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Skin Irrit. 2 |
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616-572-5
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7790-84-3
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yes |
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