Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed

Acute toxicity: via inhalation route

Endpoint conclusion
Dose descriptor:
LC50
Value:
4 970 mg/m³

Acute toxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Based on the available study concerning the Acute Toxicity via Oral route, charcoal has beneficial effects (2.5 g/kg b.w./day) on Zanzibar red colobus monkey i.e. higher birth rate and population densities.

Also, according to the testing results for the Acute Inhalation lethal concentration LC50 > 4.97 mg/L.

Finally, as oral and inhalation routes of exposure are more relevant and data for these have been provided, testing for acute dermal toxicity is therefore waived based on this information. Furthermore, dermal toxicity of the substance is insignificant, based and on its low water solubility and the granulometry of the subsstance.

Justification for classification or non-classification

Based on the available data for acute toxicity and the physical and chemical properties of the substance, we can conclude that charcoal is not responsible for classification.