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Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)
Additional information:

An LLNA has been conducted with DVB-55 a reaction mass of ca. 55% divinylbenzene and ca. 45% ethylstyrene. Based on the results of this study DVB-55 is considered to be a weak sensitizer (EC3 = 10.9). Other grades of this reaction mass (DVB-HP and DVB-63) are expected to give similar results and are therefore considered to be sensitizers as well. For animal welfare reasons no further sensitization testing has been performed with other grades of the reaction mass.

Migrated from Short description of key information:
A GLP-study conducted according to OECD guideline 429 is available for the reaction mass of divinylbenzene and ethylstyrene.

Justification for classification or non-classification

The reaction mass of divinylbenzene and ethylstyrene is considered to be a weak sensitiser based on the LLNA conducted with DVB-55. All grades of the reaction mass should be classified as a sensitiser according to EU labelling regulations Commission Directive 2001/59/EC. The symbol “Xi”, indication of danger ‘irritant’ and the risk phrase R 43 “May Cause Sensitisation by Skin Contact” are therefore required.

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