Registration Dossier
Registration Dossier
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EC number: 910-757-7 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
- Additional information:
An LLNA has been conducted with DVB-55 a reaction mass of ca. 55% divinylbenzene and ca. 45% ethylstyrene. Based on the results of this study DVB-55 is considered to be a weak sensitizer (EC3 = 10.9). Other grades of this reaction mass (DVB-HP and DVB-63) are expected to give similar results and are therefore considered to be sensitizers as well. For animal welfare reasons no further sensitization testing has been performed with other grades of the reaction mass.
Migrated from Short description of key information:
A GLP-study conducted according to OECD guideline 429 is available for the reaction mass of divinylbenzene and ethylstyrene.
Justification for classification or non-classification
The reaction mass of divinylbenzene and ethylstyrene is considered to be a weak sensitiser based on the LLNA conducted with DVB-55. All grades of the reaction mass should be classified as a sensitiser according to EU labelling regulations Commission Directive 2001/59/EC. The symbol “Xi”, indication of danger ‘irritant’ and the risk phrase R 43 “May Cause Sensitisation by Skin Contact” are therefore required.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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