Registration Dossier
Registration Dossier
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EC number: 910-757-7 | CAS number: -
Developmental toxicity / teratogenicity
Administrative data
- Endpoint:
- developmental toxicity
- Type of information:
- experimental study planned
- Study period:
- within 18 months of the final decision
- Justification for type of information:
- study is a mandatory requirement for substances >1000t. There are very limited opportunities to waive the study.
- Available GLP studies - none
- Available non-GLP studies - none
- Grouping and read-across - not appropriate
- Historical human data - none
- (Q)SAR - not valid for this endpoint
- In vitro methods - not valid for this endpoint
- Weight of evidence - no studies with which to form weight of evidence
- Substance-tailored exposure driven testing [if applicable] - not appropriate for this endpoint considering the uses and the extremely limited circumstances where an exposure base waiving argument is acceptable
Data source
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 414 (Prenatal Developmental Toxicity Study)
Test material
- Reference substance name:
- Divinylbenzene
- EC Number:
- 215-325-5
- EC Name:
- Divinylbenzene
- Cas Number:
- 1321-74-0
- Molecular formula:
- C10H10
- IUPAC Name:
- Benzene, diethenyl-
- Reference substance name:
- Ethylstyrene
- EC Number:
- 248-846-1
- EC Name:
- Ethylstyrene
- Cas Number:
- 28106-30-1
- Molecular formula:
- C10H12
- IUPAC Name:
- Benzene, ethenylethyl-
- Test material form:
- liquid
- Details on test material:
- Exact composition of test material to be agreed with other registrants based on what is the most representative composition
Constituent 1
Constituent 2
Test animals
- Species:
- rabbit
Administration / exposure
- Route of administration:
- oral: gavage
Results and discussion
Results (fetuses)
Fetal abnormalities
- Key result
- Abnormalities:
- not specified
Overall developmental toxicity
- Key result
- Developmental effects observed:
- not specified
Applicant's summary and conclusion
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