Reaction mass of divinylbenzene and ethylstyrene

Water solubility

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Principles of method if other than guideline:

Nephelometric method, ref. Determination of Water Solubility by Nephelometric Method, T3.07-000-000-011, The Dow Chemical Company, 1976.

GLP compliance:

no

Type of method:

other: Nephelometric method, ref. Determination of Water Solubility by Nephelometric Method, T3.07-000-000-011, The Dow Chemical Company, 1976.

Water solubility:

44 mg/L

Temp.:

25 °C

pH:

ca. 7

Conclusions:

The water solubility for Divinylbenzene-55 is 44 mg/L.

Executive summary:

Screening tests were run on a sample of divinylbenzene-55 (DVB-55) and the following conclusions may be made:

Movement

Water solubility is 44 mg/L and the vapor pressure is 1.0 mm Hg at 33 °C. Removal after 1 hour aeration was 96% by sensitive dichromate analysis and 100% after 4 hours.

Stability

DBV-55 does not consume oxygen in the standard 20-day BOD test and will probably not degrade i n a biological wastewater treatment plant.

Bioconcentration

DVB-55 has a predicted bioconcentration factor (BCF) of 184 which may be contrasted with PCB which has a BCF of 10000 or more. The persistence of DVB-55 in the aquatic environment is unknown.

Fish toxicity

DVB-55 showed 96-hr LC 10-50-90 values of 6.6 (4.4-7.2)*, 7.5 (6.5-8.1) , and 8.6 (8.1-10.8) mg/L, respectively, to fathead minnows, Pimephales promelas Rafinesque, in static water tests.

*95% Confidence Interval

Reference 2

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

19 December 2009 to 09 February 2010

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

GLP compliance:

yes

Remarks:

Date of GLP inspection: 15 September 2009 Date of Signature on GLP certificate: 26 November 2009

Type of method:

flask method

Water solubility:

0.036 g/L

Temp.:

20 °C

pH:

>= 6.8 - <= 7

Details on results:

The preliminary estimate of water solubility was 7.37 x 10-3 g/L.
The water solubility of the test material has been determined to be 3.62 x 10-2 g/L of solution at 20.0 ± 0.5°C

Definitive test

The mean total peak areas relating to the standard and sample solutions are shown in the following table:

Solution	MeanArea
Standard 12.2 mg/L	0.332
Standard 12.2 mg/L	0.384
Sample 1A	0.536
Sample 1B	0.518
Sample 2A	0.518
Sample 2B	0.504
Sample 3A	0.569
Sample 3B	0.541

The concentration (g/L) of test material in the sample solutions is shown in the following table:

Sample Number	Time Shaken at ~ 30ºC (hours)	Time Equilibrated at 20ºC (hours)	Concentration (g/L)	Solution pH
1	24	24	3.59 x 10^-2	7.0
2	48	24	3.48 x 10^-2	6.8
3	72	24	3.79 x 10^-2	6.8

Mean concentration:         3.62 x 10^-2 g/L at 20.0 ± 0.5ºC
Range:                             3.48 x 10^-2 to 3.79 x 10^-2 g/L

Validation

The linearity of the detector response with respect to concentration was assessed over the nominal concentration range of 4 to 40 mg/L. This was satisfactory with a correlation coefficient of 0.999 being obtained.

Typical chromatgraphy - see attachment 1

Conclusions:

The water solubility of the test material has been determined to be 3.62 e-2 g/L of solution at 20.0 ± 0.5°C.

Executive summary:

Water Solubility.  3.62 x 10^-2 g/L of solution at 20.0 ± 0.5°C, using the flaskthod, Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

Description of key information

Water solubility of DVB-55 = 44 mg/L at 25°C

Water solubility of DVB-HP = 36 mg/L at 20°C

Key value for chemical safety assessment

Water solubility:

36 mg/L

at the temperature of:

20 °C

Additional information

Reported measured water solubility values range from 36-52 mg/L for different grades of the reaction mass of divinylbenzene and ethylstyrene. Reported but undocumented values for positional isomers of DVB are 8.2 and 20 mg/L. Measurement of water solubility of these substances can be influenced by volatility and must be considered as "suspect" unless available documentation describes methodology which is suitable for testing of volatile substances. The documented Key Study for DVB-HP, giving a value of 36 mg/L, is considered to be a reliable determination of the water solubility of the reaction mass.