Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 910-757-7 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
The components of DVB-55, -65, and -HP have exhibited little or no biodegradation in screening tests of ready biodegradability. A study of biodegradation in surface water/sediment was conducted according to OECD Guideline 309.
Primary degradation of [14C]1,3 EVB and [14C]1,4 DVB to more polar [14C]-degradation products occurred in surface water and surface water/sediment mixtures with half-lives ranging from 3.8 to 31.4 days over the test concentration range of 50 to 1500 µg/L.
Mineralization of [14C]1,3 EVB to14CO2 reached 19.8 and 67.7% of applied radioactivity within 49 days at 50 and 500 µg/L, respectively, in the presence of sediment while mineralization was limited in surface water alone (3%). Little mineralization of [14C]1,4 DVB(<1%) occurred in the reaction mixtures under the conditions of the test.
The half-lives for the parent compounds 1,3-EVB and 1,4-DVB are less than the criteria for persistence in surface water (i.e. 40 days in fresh water). Inspection of the tables in the study report listing metabolites as a percentage of applied radioactivity at each sampling point illustrates an overall progression of multiple metabolites to shorter HPLC retention times over time. In the reverse-phase HPLC assay used in the study, shorter retention times correlate with more polar, water soluble metabolites. The progression to shorter retention times indicates that these metabolites themselves are not persistent, but rather continue to degrade to simpler, more polar compounds.
Efforts were made to structurally characterize transformation products formed during aerobic mineralization of DVB-55 in surface water that represented >10% of the administered radioactive dose. Selected samples were subjected to analysis by GC/MS and LC/MS by Electrospray Ionization in the positive and negative ionization modes (ESI (+/-)), Atmospheric Pressure Chemical Ionization (APCI (+/-)), and Atmospheric Pressure Photo Ionization (APPI). Due to the insufficient amount of mass of the unknown(s), no conclusive identification could be made from the analysis results generated in this study.
Attempts to identify the metabolites using a variety of analytical techniques were unsuccessful due to insufficient amounts of the unknowns available for characterization.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
