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The bioconcentrationpotential (bioconcentration factor, BCF) of the four major constituents in divinylbenzene (DVB-55) have been assessed using a quantitative structure-activity relationship (QSAR) model (BCF baseline model v.02.06) as described by Dimitrov et al (2005) and implementedin OASIS CATALOGIC v 5.11.12.. The prediction for the constituents of DVB-55 support the experimental data in Carp, indicating that DVB-55 is not bioaccumulative with high confidence, as BCF values range from 219 and 302 L/kg.

The bioconcentration factor in Cyprinus carpio was 229-433 and 206-415 at 2.5 and 25 ug/L, respectively. The mid-point of these measured values, BCF = 320 L/kg wet wt., is used to represent BCF of the substance components in the chemical safety assessment.

The QSAR predictions are within the same range, as measured in Carp, which is chosen as a key value for the chemical safety assessment.

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