Previous Testing Proposals
Previous Testing Proposals
Previous Testing Proposals
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
Dihydrogen hexahydroxyplatinate | 257-471-2 | 51850-20-5 | Genetic toxicity in vivo || Note: Testing proposed with dihydrogen hexahydroxyplatinate(IV), compound with 2-aminoethanol (1:2). Testing proposal is based on concern identified by the registrant. | 28/02/2018 | 16/04/2018 | Details | |
Dimethylamine | 204-697-4 | 124-40-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2018 | 16/04/2018 | Details | |
Fatty acids, tall-oil, compds. with N-[3-(dimethylamino)propyl]tall-oil amides | 295-714-4 | 92128-22-8 | Reproductive toxicity (pre-natal developmental toxicity) | 28/02/2018 | 16/04/2018 | Details | |
Hexahydro-4-methylphthalic anhydride | 243-072-0 | 19438-60-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2018 | 16/04/2018 | Details | |
Reaction products of di-, tri- and tetra-propoxylated propane-1,2-diol with ammonia | 618-561-0 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2018 | 16/04/2018 | Details | |
Tetraammineplatinum dichloride | 237-706-5 | 13933-32-9 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 28/02/2018 | 16/04/2018 | Details | |
Tetraammineplatinum dinitrate | 243-929-9 | 20634-12-2 | Genetic toxicity in vivo || Note: testing proposed with tetraammineplatinum(II) dichloride. Testing proposal is based on concern identified by the registrant. | 28/02/2018 | 16/04/2018 | Details | |
Vinyl neononanoate | 259-160-7 | 54423-67-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2018 | 16/04/2018 | Details | |
Polysulfides, di-tert-dodecyl | 270-335-7 | 68425-15-0 |
Sub-chronic toxicity (90-day): oral Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
31/01/2018 31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 19/03/2018 |
Details | |
2,4,6,8,10-pentamethylcyclopentasiloxane | 228-204-7 | 6166-86-5 |
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (CAS 2370-88-9; EC 219-137-4; HD4) Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (CAS 2370-88-9; EC 219-137-4; HD4) |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
|
Details |
2-(4-fluorophenyl)-5-(5-iodo-2-methylbenzyl)thiophene | 618-312-6 | 898566-17-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
Details | |
[[(phosphonomethyl)imino]bis[hexamethylenenitrilobis(methylene)]]tetrakisphosphonic acid | 252-156-6 | 34690-00-1 |
Sub-chronic toxicity (90-day): oral || Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
Details | |
Amines, polyethylenepoly-, tetraethylenepentamine fraction | 292-587-7 | 90640-66-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with TETA (CAS 90640-67-8) and HEPA (68121-73-7) Reproductive toxicity (pre-natal developmental toxicity ) |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
Details | |
Ashes (residues), plant | 297-049-5 | 93333-79-0 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
Details | |
Ditetradecyl peroxydicarbonate | 258-436-4 | 53220-22-7 |
Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
Details | |
Potassium salts of {hexane-1,6-diylbis[nitrilobis(methylene)]}tetrakisphosphonic acid (4-7:1) | 701-184-1 | - |
Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
Details | |
Reaction products of pentaerythritol, propoxylated and 1-chloro-2,3-epoxypropane with hydrogen sulfide | 701-196-7 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
Details | |
Biphenyl | 202-163-5 | 92-52-4 | Reproductive toxicity (pre-natal developmental toxicity) | 31/01/2018 | 19/03/2018 | Details | |
Everzol Red CDN Crude | 483-940-8 | - | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 31/01/2018 | 19/03/2018 | Details | |
Octadecanoic acid, sulfonated, potassium salt | 701-179-4 | - | Sub-chronic toxicity (90-day): oral || Note: The List number has changed. | 31/01/2018 | 19/03/2018 | Details | |
Pivalic acid | 200-922-5 | 75-98-9 |
Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (extended one-generation reproductive toxicity study) |
20/12/2017 20/12/2017 20/12/2017 |
05/02/2018 05/02/2018 05/02/2018 |
Details | |
2-(2-Vinyloxyethoxy)ethyl acrylate | 451-690-9 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
20/12/2017 20/12/2017 |
05/02/2018 05/02/2018 |
Details | |
pentaerythritol | 204-104-9 | 115-77-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
20/12/2017 20/12/2017 |
05/02/2018 05/02/2018 |
Details | |
Isotridecan-1-ol | 248-469-2 | 27458-92-0 | Reproductive toxicity (pre-natal developmental toxicity) | 20/12/2017 | 05/02/2018 | Details | |
1,4-phenylene bis[(4-phenoxyphenyl)-methanone] | 620-097-9 | 54299-17-1 |
Bioaccumulation aquatic / sediment Long-term toxicity to fish |
22/11/2017 22/11/2017 |
08/01/2018 08/01/2018 |
Details | |
2,4,6,8-tetramethylcyclotetrasiloxane | 219-137-4 | 2370-88-9 |
Sub-chronic toxicity (90-day): oral - |
22/11/2017 22/11/2017 |
08/01/2018 08/01/2017 |
Details | |
3,6,9,12-tetraazatetradecamethylenediamine | 223-775-9 | 4067-16-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with structural analogues TETA (CAS 90640-67-8) and HEPA (CAS 68121-73-7). Reproductive toxicity (pre-natal developmental toxicity) |
22/11/2017 22/11/2017 |
08/01/2018 08/01/2018 |
Details | |
a,a-dimethylphenethyl butyrate | 233-221-8 | 10094-34-5 |
Sub-chronic toxicity (90-day): oral“|| Note: testing proposed 1,1-Dimethyl-2-phenylethyl acetate (EC 205-781-3)” Reproductive toxicity (pre-natal developmental toxicity)“|| Note: testing proposed 1,1-Dimethyl-2-phenylethyl acetate (EC 205-781-3)” |
22/11/2017 22/11/2017 |
08/01/2018 08/01/2018 |
Details | |
Amines, polyethylenepoly-, triethylenetetramine fraction | 292-588-2 | 90640-66-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
22/11/2017 22/11/2017 |
08/01/2018 08/01/2018 |
|
Details |
4-phenylbutan-2-one | 219-847-4 | 2550-26-7 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with a read-across substance having similar formula structure and its carbon chain consists of even number of carbons | 22/11/2017 | 08/01/2018 | Details | |
Amines, polyethylenepoly- | 268-626-9 | 68131-73-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 22/11/2017 | 08/01/2018 | Details | |
Glycerol, propoxylated, esters with acrylic acid | 500-114-5 | 52408-84-1 | Sub-chronic toxicity (90-day): oral | 22/11/2017 | 08/01/2018 | Details | |
(-)-pin-2(3)-ene | 232-077-3 | 7785-26-4 | Reproductive toxicity (pre-natal developmental toxicity) | 25/10/2017 | 11/12/2017 | Details | |
2,2'-[hexane-1,6-diylbis(oxymethylene)]dioxirane | 618-939-5 | 933999-84-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/10/2017 | 11/12/2017 | Details | |
4'-hydroxyacetophenone | 202-802-8 | 99-93-4 | Reproductive toxicity (pre-natal developmental toxicity) | 25/10/2017 | 11/12/2017 | Details | |
Benzenamine, N-phenyl-, reaction products with 2,4,4-trimethylpentene | 270-128-1 | 68411-46-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/10/2017 | 11/12/2017 | Details | |
Decamethylcyclopentasiloxane | 208-764-9 | 541-02-6 | Reproductive toxicity (pre-natal developmental toxicity) | 25/10/2017 | 11/12/2017 | Details | |
Geraniol | 203-377-1 | 106-24-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/10/2017 | 11/12/2017 | Details | |
Slags, silicomanganese-manufg. | 273-733-9 | 69012-33-5 | Reproductive toxicity (pre-natal developmental toxicity)|| Note: testing proposed with Slags, ferromanganese-manufg. CAS No 69012-28-8 (EC No 273-728-1) | 25/10/2017 | 11/12/2017 | Details | |
tetraammine platinum (II) hydrogen carbonate | 426-730-3 | 123439-82-7 | Genetic toxicity in vivo|| Note: Testing proposed with tetraammineplatinum(II) dichloride. Testing proposal is based on concern identified by the registrant. | 25/10/2017 | 11/12/2017 | Details | |
2,2',6,6'-Tetrabromo-4,4'-isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane | 500-107-7 | 40039-93-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
27/09/2017 27/09/2017 27/09/2017 |
13/11/2017 13/11/2017 13/11/2017 |
Details | |
Reaction mass of 2-(1,1-dimethylpropyl)anthraquinone and 2-(1,2-dimethylpropyl)anthraquinonedimethylpropyl)anthraquinone | 915-623-1 | - |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
27/09/2017 27/09/2017 27/09/2017 |
13/11/2017 13/11/2017 13/11/2017 |
Details | |
Triethoxyoctylsilane | 220-941-2 | 2943-75-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
27/09/2017 27/09/2017 27/09/2017 |
13/11/2017 13/11/2017 13/11/2017 |
Details | |
3-Ethenyl-5-methyl-2-oxazolidinone | 809-852-5 | 3395-98-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
27/09/2017 27/09/2017 |
13/11/2017 13/11/2017 |
Details | |
Trimethoxyoctylsilane | 221-338-7 | 3069-40-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study || Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1) Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1) |
27/09/2017 27/09/2017 |
13/11/2017 13/11/2017 |
Details | |
Bisdecanoyl peroxide | 212-092-1 | 762-12-9 | Long-term toxicity to fish | 27/09/2017 | 13/11/2017 | Details | |
Silver | 231-131-3 | 7440-22-4 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with silver(1+) acetate (CAS number 563-63-3) | 27/09/2017 | 13/11/2017 | Details | |
Bis[C5-(branched)-alkyl]l benzene-1,4-dicarboxylate | 940-272-6 | - |
Sub-chronic toxicity (90-day): oral Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity |
01/09/2017 01/09/2017 01/09/2017 |
16/10/2017 16/10/2017 16/10/2017 |
Details | |
2,2'-iminodi(ethylamine) | 203-865-4 | 111-40-0 |
Reproductive toxicity (extended one-generation reproductive toxicity study Reproductive toxicity (pre-natal developmental toxicity) |
01/09/2017 01/09/2017 |
16/10/2017 16/10/2017 |
Details | |
3,5-dimethyl-1,2-dioxolane-3,5-diol | 237-438-9 | 13784-51-5 |
Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) |
01/09/2017 01/09/2017 |
16/10/2017 16/10/2017 |
Details | |