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EC number: 204-464-7 | CAS number: 121-32-4
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Remarks:
- No test substance information and little information about the method, but method scientifically sound, precautions were taken not to contaminate the water phases with the octanol phase. Moreover the comparison with two referent substances shows that the study can be considered as valid for this endpoint.
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Deviations:
- not specified
- GLP compliance:
- not specified
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 1.58
- Temp.:
- 25 °C
- Remarks on result:
- other: no data available on pH
- Conclusions:
- Ethylvanillin has a low potential of bioaccumulation.
- Executive summary:
In a study (Bazaco et al, 1989), the partition coefficient of ethylvanillin was measured using the shake flask method.
The log Kow found was 1.58 at 25°C.
In these conditions, ethylvanillin has a low potential of bioaccumulation.
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Remarks:
- The method followed OECD guideline 107 but only little information on the test conditions is available.
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Deviations:
- not specified
- GLP compliance:
- not specified
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 1.61
- Temp.:
- 25 °C
- Remarks on result:
- other: Experimental value
- Details on results:
- No information is given about preliminary estimation and the concentrations between different runs of the experiment.
- Conclusions:
- Ethylvanillin has a low potential of bioaccumulation.
- Executive summary:
In a study (Smith et al,2002; Jin, 1998; Dai, 2001), the partition coefficient of ethylvanillin was measured using the shake flask method.
The log Kow found was 1.61 at 28°C.
In these conditions, ethylvanillin has a low potential of bioaccumulation.
Referenceopen allclose all
No more data on results.
Description of key information
Partition coefficient range: 1.58 to 1.61 at 25°C, from experimental studies.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 1.58
- at the temperature of:
- 25 °C
Additional information
Two experimental studies (Bazaco et al., 1989 and Smith et al., 2002) were available and were selected as key studies. Their results gave a log Kow in a range from 1.58 to 1.61 at 25°C.
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