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EC number: 202-486-1 | CAS number: 96-18-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
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- Nanomaterial surface chemistry
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- Nanomaterial pour density
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- Endpoint summary
- Stability
- Biodegradation
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- Environmental data
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- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
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- Long-term toxicity to aquatic invertebrates
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- Endocrine disrupter testing in aquatic vertebrates – in vivo
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- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
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- Genetic toxicity
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- Specific investigations
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- Additional toxicological data

Henry's Law constant
Administrative data
Link to relevant study record(s)
- Endpoint:
- Henry's law constant
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The Henry's Law constants were determined for a temperature range from 25 to 45 °C on the basis of acceptable scientific principles. The documentation of the methods and results is sufficient to consider the results as reliable with restrictions.
- Principles of method if other than guideline:
- The Henry's Law constant for 1,2,3-trichloropropane was determined over the temperature range from 26.5 to 45 °C by measuring the equilibrium concentrations of the substance in air and water, using simultaneous sampling from sealed bottles kept at constant temperatures.
- GLP compliance:
- not specified
- H:
- 0.01 dimensionless
- Temp.:
- 26.5 °C
- Atm. press.:
- 1 013 hPa
- H:
- 0.01 dimensionless
- Temp.:
- 27.4 °C
- Atm. press.:
- 1 013 hPa
- H:
- 0.01 dimensionless
- Temp.:
- 28.9 °C
- Atm. press.:
- 1 013 hPa
- H:
- 0.012 dimensionless
- Temp.:
- 29.7 °C
- Atm. press.:
- 1 013 hPa
- H:
- 0.011 dimensionless
- Temp.:
- 29.9 °C
- Atm. press.:
- 1 013 hPa
- H:
- 0.013 dimensionless
- Temp.:
- 33.3 °C
- Atm. press.:
- 1 013 hPa
- H:
- 0.017 dimensionless
- Temp.:
- 40 °C
- Atm. press.:
- 1 013 hPa
- H:
- 0.02 dimensionless
- Temp.:
- 45 °C
- Atm. press.:
- 1 013 hPa
- Conclusions:
- The dimensionless Henry's Law constant for 1,2,3-trichloropropane was determined by simultaneous analysis of equilibrium concentrations in air and water over a temperature range from 26.5 to 45 °C resulting in values ranging from 0.01 to 0.02.
- Executive summary:
The Henry's Law constant of 1,2,3-trichloropropane was determined over the temperature range from 26.5 to 45 °C by measuring the equilibrium concentrations of the substance in air and water, using simultaneous sampling from sealed bottles kept at constant temperatures. The values for the dimensionless Henry's Law constant ranged from 0.01 at 26.5 °C to 0.02 at 45 °C.
Reference
The results of a second test phase divided from those of the first phase in the sense that there was an anomaly due to a difference in the range of the air and water standard curves for the substance in the two experimental phases. In the publication it is recommended to use the values of the second phase which are given above.
Description of key information
Key value for chemical safety assessment
Additional information
The Henry’s Law Constant of TCP was calculated with the EUSES model, which gives a value of 13.9 Pa x m3 / mol at 12 °C and 1013 hPa (Wormuth 2010b). Based on the measured Henry’s Law Constant of 22.8 Pa x m3 / mol (Tancrède and Yanagisawa 1990) it is expected that TCP has a moderate volatility from the aqueous phase. Experimental data show that the half-life for stripping of TCP from water is between 1 and 1.5 hours (Dilling 1977, Albanese et al. 1987). On the other hand, significant amounts of TCP may be washed out from the atmosphere by wet deposition considering the water solubility of 1.75 g/L for TCP (WHO 2003).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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