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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

The following results were determined for the test item reaction mass of 2,2'-oxybisbutane (DSBE), DIPE, SBA and 2-methylpropan-2-ol (TBA) (species: Danio rerio): 24h, 48h, 72h and 96h-NOEC = 71 mg/L;   24h, 48h, 72h and 96h-LC50 >71 mg/L; 24h, 48h, 72h and 96h-LC100 > 71 mg/L. 
Based on these data in combination with the fact that the substance is not readily biodegradable, a classification into aquatic chronic category 3 (H412) (corresponding to R52/53) is necessary (LC50 10-100 mg/l).

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
71 mg/L

Additional information

The LC50 value and the NOEC for the mortality of Danio rerio of reaction mass of 2,2'-oxybisbutane (DSBE), DIPE, SBA and 2-methylpropan-2-ol (TBA) was measured according to OECD 203, respectively EU C.1 guideline under GLP. Following results were obtained: 96h-NOEC = 71 mg/L; 96h-LC50 > 71 mg/L

The measured concentrations are higher than the nominal concentration. As no mortality occurred, this is stated as uncritical. The analytical determinations of the test item showed good correlation between old and new test solutions. The determination of the results was based on the geometric mean of the concentrations.

Based on these data in combination with the fact that the substance is not readily biodegradable, a classification into aquatic chronic category 3 (H412) according to the CLP regulation (corresponding to R52/53) is necessary (LC50 10-100 mg/l).

Based on the lowest EC/LC50 value of the three species daphnia, algae and fish (available studies), an aquatic PNEC value was calculated for the risk assessment.

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