Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Toxicity to reproduction

Currently viewing:

Administrative data

two-generation reproductive toxicity
based on test type (migrated information)
Type of information:
experimental study planned
Study period:
Should be available approximately 18 months after dosing commences. Planned Studies on DIPE (CAS 108-20-3) should be completed before commencing tests since a positive result in that study will result in a positive result for OC4 Strom4.

Data source

Materials and methods

Test guideline
according to guideline
OECD Guideline 416 (Two-Generation Reproduction Toxicity Study)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
2-(butan-2-yloxy)butane; 2-(propan-2-yloxy)propane; 2-methylpropan-2-ol; butan-2-ol
EC Number:
Molecular formula:
Not applicable as multiconstituent substance.
2-(butan-2-yloxy)butane; 2-(propan-2-yloxy)propane; 2-methylpropan-2-ol; butan-2-ol

Test animals


Results and discussion

Overall reproductive toxicity

Reproductive effects observed:
not specified

Applicant's summary and conclusion