Registration Dossier

Diss Factsheets

Toxicological information

Toxicity to reproduction

Currently viewing:

Administrative data

Endpoint:
two-generation reproductive toxicity
Remarks:
based on test type (migrated information)
Type of information:
experimental study planned
Study period:
Should be available approximately 18 months after dosing commences. Planned Studies on DIPE (CAS 108-20-3) should be completed before commencing tests since a positive result in that study will result in a positive result for OC4 Strom4.

Data source

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 416 (Two-Generation Reproduction Toxicity Study)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
2-(butan-2-yloxy)butane; 2-(propan-2-yloxy)propane; 2-methylpropan-2-ol; butan-2-ol
EC Number:
903-919-3
Molecular formula:
Not applicable as multiconstituent substance.
IUPAC Name:
2-(butan-2-yloxy)butane; 2-(propan-2-yloxy)propane; 2-methylpropan-2-ol; butan-2-ol

Test animals

Species:
rat

Results and discussion

Overall reproductive toxicity

Reproductive effects observed:
not specified

Applicant's summary and conclusion