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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

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Description of key information

The following results were determined for the test item reaction mass of 2,2'-oxybisbutane (DSBE), DIPE, SBA and 2-methylpropan-2-ol (TBA)  
3h EC50 = 2400 mg/L (95% confid. interv.: 1000 - 7300 mg/L)

Key value for chemical safety assessment

EC50 for microorganisms:
2 400 mg/L

Additional information

The EC20 value, EC50 value and the NOEC for the inhibition of the respiration in activated sludge of reaction mass of 2,2'-oxybisbutane (DSBE), DIPE, SBA and 2-methylpropan-2-ol (TBA) was measured according to OECD 209, respectively EU C.11 guideline under GLP. Following results were obtained:

3h NOEC = 32 mg/L
3h EC20 = 400 mg/L (95% confid. interv.: 120 - 970 mg/L)

3h EC50 = 2400 mg/L (95% confid. interv.: 1000 - 7300 mg/L)

These values are not used for classification and labelling since no endpoint exists for toxicity to microorganisms. In the risk assessment,

the EC50 value is used for the calculation of the PNEC for microorganisms in sewage treatment plants (PNEC STP).