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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Reference
Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods with acceptable restrictions
Remarks:
National guideline study with acceptable restrictions
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 305 C (Bioaccumulation: Test for the Degree of Bioconcentration in Fish)
Deviations:
not specified
GLP compliance:
not specified
Test organisms (species):
Cyprinus carpio
Details on test organisms:
Fish were acclimated at a temperature of 25 +/- 2 °C for about 2 month.
Size of the test fish at the initiation of exposure:
Weight: about 30 g
Length: about 10 cm
Lipid content: 2 - 6%
Route of exposure:
aqueous
Test type:
flow-through
Water / sediment media type:
natural water: freshwater
Total exposure / uptake duration:
56 d
Test temperature:
25 +/- 2 °C
Dissolved oxygen:
6 - 8 mg/L
Details on test conditions:
Flow rate of test water: 200 - 800 mL/min
Nominal and measured concentrations:
0.1 mg/l
Details on estimation of bioconcentration:
BCF = concentration of test substance in fish / concentration of test substance in water
Type:
BCF
Value:
150 - 230
Basis:
whole body w.w.
Calculation basis:
steady state
Remarks on result:
other: Conc.in environment / dose:0.1 mg/L
Type:
BCF
Value:
90 - 260
Basis:
whole body w.w.
Calculation basis:
steady state
Remarks on result:
other: Conc.in environment / dose:0.01 mg/L
Conclusions:
Bioconcentration factors ranging from 90 to 260 have been found for fish (Cyprinus carpio) exposed to 1,2 -dichlorobenzene for 56 days.
Executive summary:

MITI (1992).

Bioconcentration factors ranging from 90 to 260 have been found for fish (Cyprinus carpio) exposed to 1,2 -dichlorobenzene for 56 days. The test was conducted according to a national guideline which corresponds to OECD Guideline 305C (1981).

Description of key information

Bioconcentration factors for the whole organism ranging from 90 to 260 have

been found for fish (Cyprinus carpio) exposed to 1,2 -dichlorobenzene for 56 days (MITI, 1992). The test was conducted according to a national guideline which corresponds to OECD Guideline 305C (1981).

Key value for chemical safety assessment

BCF (aquatic species):
260 dimensionless

Additional information

Bioconcentration factors for the whole organism ranging from 90 to 260 have been found for fish (Cyprinus carpio) exposed to 1,2 -dichlorobenzene for 56 days (MITI, 1992). The test was conducted according to a national guideline which corresponds to OECD Guideline 305C (1981).

Further studies have been published revealing BCF values in terms of whole organisms for freshwater and saltwater fish and invertebrates in the same order of magnitude. In terms of lipid content, BCF values were between 6166 (spottet sea trout) to 28840 (Blue crab). For cyanobacteria and algae, BCF values of 6212 and 29700 were reported.

However, the maximum BCF value for whole fish of 260 has been selected as the key value for bioaccumulation in the aquatic environment.