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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods with acceptable restrictions
Qualifier:
according to guideline
Guideline:
other: US EPA (1993): Methods for measuring the acute toxicity of effluents and receiving waters to freshwater and marine organisms, 4th ed. Weber CI (ed) EPA report EPA/600/4-90/027F, Washington DC, 293 pp
Deviations:
not specified
Qualifier:
according to guideline
Guideline:
other: ASTM (1992): Standard guide for conducting acute toxicity tests on aqueous effluents with fishes, macroinvertebrates, and amphibians. American Society for Testing and Materials, Designation E1192-88. Philadelphia, PA, vol 11.04, 812-828
Deviations:
not specified
Qualifier:
according to guideline
Guideline:
other: Warne MStJ (1996): Acute toxicity of laundry detergents to an Australian cladoceran (Ceriodaphnia c.f. dubia). Australas J Ecotox 1: 127-135
Deviations:
not specified
GLP compliance:
not specified
Analytical monitoring:
yes
Test organisms (species):
Ceriodaphnia dubia
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
48 h
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
4.5 µmol/L
Nominal / measured:
meas. (initial)
Conc. based on:
not specified
Basis for effect:
mobility
Remarks on result:
other: 3.0 - 6.7
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
0.66 mg/L
Nominal / measured:
meas. (initial)
Basis for effect:
mobility
Conclusions:
The short term toxicity of Ceriodaphnia dubia Richard to 1,2 dichlorobenzene was determined in a laboratory study by Rose et al (1998) according to standard methods (Warne 1996) based on US EPA methods (US EPA 1993) and ASTM (1988). The EC50 (48 h) was reported as 0.66 mg/L (initially measured concentration).
Executive summary:

Rose et al. (1998).

The EC50 (48 h) for Ceriodaphnia dubia Richard was determined in a laboratory study according to standard methods (Warne 1996) based on US EPA methods (US EPA 1993) and ASTM (1988) to be 0.66 mg/L (initially measured concentration).

Remark: The EC50 (48 h) was originally reported to be 4.5 µmol/L (95% CV: 3.0 - 6.7 µmol/L) (initially measured concentration).

Description of key information

The short term toxicity of Ceriodaphnia dubia Richard to 1,2 dichlorobenzene was determined in a laboratory study by Rose et al (1998) according to standard methods (Warne 1996) based on US EPA methods (US EPA 1993) and ASTM (1988).  The EC50 (48 h) was reported as 0.66 mg/L (initially measured concentration).

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
0.66 mg/L

Additional information

The short term toxicity of Ceriodaphnia dubia Richard to 1,2 dichlorobenzene was determined in a laboratory study by Rose et al (1998) according to standard methods (Warne 1996) based on US EPA methods (US EPA 1993) and ASTM (1988). The EC50 (48 h) was reported as 0.66 mg/L (initially measured concentration) and this was considered the key endpoint for acute toxicity of

1,2 dichlorobenzene to aquatic invertebrates.