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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 123 (Partition Coefficient (1-Octanol / Water), Slow-Stirring Method)
Deviations:
yes
Remarks:
Analytical purity not reported.
GLP compliance:
no
Type of method:
other: slow-stirring method
Partition coefficient type:
octanol-water
Type:
log Pow
Partition coefficient:
ca. 3.433
Temp.:
25 °C
Remarks on result:
other: pH value not specified

1,2 -Dichlorobenzenes: Log Kow values measured by slow-stirring method and comparison with literature values

Literature values

log Kow (+-SD)                           Shake-flask                Calculated                              HPLC b          Generator columnc

3.433 +-0.023                      3.40 d , 3.38e, 3.55 f         3.65                                         3.46                     3.38

aCalculated according to Rekker, using benzene (log Kow=2.13) as parent compound; f values from Rekker and de Kort.

b HPLC values from Hammers et al. [Hammers et al. 1982. J.Chromtogr 247: 1 -13].

c Generator-column values from Miller [Miller et al., 1984. J Chem Eng, Data 29:184 -190]

d Banerjee et al. [Banerjee S et al. 1980. Environ. Sci. Technol. 14:1227 -1229]

e Hansch and Leo [Hansch C and Leo AJ 1979. John Wiley and Sons, New York, NY].

f Könemann et al. [Könemann et al., 1979. J. Chromatogr178: 559 -565]

Conclusions:
The logKow of the substance was determined with the slow stirring method at a temperature of 25°C to be logKow= 3.433.
Executive summary:

The logKow of the substance was determined with the slow stirring method at a temperature of 25°C to be logKow= 3.433.

Description of key information

The partition coefficient of o-dichlorobenzene (1,2 -Dichlorobenzene) is

determined to be log Pow = 3.433 at 25°C.

Key value for chemical safety assessment

Log Kow (Log Pow):
3.433
at the temperature of:
25 °C

Additional information

There are several valid results available for the logKow of the substance. The highest value was chosen as key study displaying a worst case.