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EC number: 202-425-9 | CAS number: 95-50-1
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 123 (Partition Coefficient (1-Octanol / Water), Slow-Stirring Method)
- Deviations:
- yes
- Remarks:
- Analytical purity not reported.
- GLP compliance:
- no
- Type of method:
- other: slow-stirring method
- Partition coefficient type:
- octanol-water
- Type:
- log Pow
- Partition coefficient:
- ca. 3.433
- Temp.:
- 25 °C
- Remarks on result:
- other: pH value not specified
- Conclusions:
- The logKow of the substance was determined with the slow stirring method at a temperature of 25°C to be logKow= 3.433.
- Executive summary:
The logKow of the substance was determined with the slow stirring method at a temperature of 25°C to be logKow= 3.433.
Reference
1,2 -Dichlorobenzenes: Log Kow values measured by slow-stirring method and comparison with literature values
Literature values
log Kow (+-SD) Shake-flask Calculated a HPLC b Generator columnc
3.433 +-0.023 3.40 d , 3.38e, 3.55 f 3.65 3.46 3.38
aCalculated according to Rekker, using benzene (log Kow=2.13) as parent compound; f values from Rekker and de Kort.
b HPLC values from Hammers et al. [Hammers et al. 1982. J.Chromtogr 247: 1 -13].
c Generator-column values from Miller [Miller et al., 1984. J Chem Eng, Data 29:184 -190]
d Banerjee et al. [Banerjee S et al. 1980. Environ. Sci. Technol. 14:1227 -1229]
e Hansch and Leo [Hansch C and Leo AJ 1979. John Wiley and Sons, New York, NY].
f Könemann et al. [Könemann et al., 1979. J. Chromatogr178: 559 -565]
Description of key information
The partition coefficient of o-dichlorobenzene (1,2 -Dichlorobenzene) is
determined to be log Pow = 3.433 at 25°C.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 3.433
- at the temperature of:
- 25 °C
Additional information
There are several valid results available for the logKow of the substance. The highest value was chosen as key study displaying a worst case.
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