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EC number: 248-953-3 | CAS number: 28305-25-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Additional information
Calcium lactate fully dissociates into Ca2+ ions and lactate- under aqueous and/or physiological conditions.The toxicological effects
of calcium lactate can be understood in terms of the toxicological effect of calcium ions and lactic acid (see read-across statement).
Lactic acid is a major and essential species in mammalian primary metabolism, and a ubiquitous ingredient in all kinds of food. Reproduction toxicity is not a relevant endpoint for such a substance since there is no way of lowering exposure below minimum required levels or normal (or even abnormal) internal levels.
Calcium ions will usually not reach the foetus or the male and female reproductive organs when exposed orally, dermally or by inhalation, as they are strictly regulated; hence, in accordance with section 1 of REACH Annex XI, testing does not appear scientifically necessary and a reproduction toxicity study was not performed.
Based on the above information calcium lactate shall not be considered to be a reproductive toxicant.
Short description of key information:
See below.
Effects on developmental toxicity
Description of key information
See below.
Additional information
Calcium lactate fully dissociates into Ca2+ ions and lactate. The toxicological effects of calcium lactate can be understood in terms of the toxicological effect of calcium chloride and lactic acid (see read-across statement).
Lactic acid is a major and essential species in mammalian primary metabolism, and a ubiquitous ingredient in all kinds of food. Developmental toxicity is not a relevant endpoint for such a substance since there is no way of lowering exposure below minimum required levels or normal (or even abnormal) internal levels.
Calcium chloride will neither reach the foetus nor the female reproductive organs ( as it does not become systemically available), which shows that there is no risk for developmental toxicity. Even so, an oral developmental study in 3 species (mouse, rat and rabbit) is available. In all three species no maternal or teratogenic effects were noted, and NOAEL 's were above highest dose given. It is confirmed that there is no concern with regard to developmental toxicity (at least up to 169 mg/kg/d for rabbits), which supports the general consideration that the substance will usually not reach the foetus.
Based on the above information calcium lactate shall not be considered to be a developmental toxicant.
Justification for classification or non-classification
Based on the above provided information, classification of calcium lactate for reproduction or developmental toxicity is not warranted in accordance with Directive 67/548/EEC and EU (CLP) Regulation (EC) No. 1272/2008.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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