Registration Dossier
Registration Dossier
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EC number: 276-431-5 | CAS number: 72162-23-3 The high-boiling fraction separated by distillation from the products obtained from the reaction of nitric acid with cyclododecanol and cyclododecanone. Composed primarily of dodecanedioic acid, undecanedioic acid, and sebacic acid.
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
No measured data was available regarding the toxicity of Corfree® M1 to aquatic plants. Using The toxicity of the read across chemical, dodecanedioic acid, on the alga Desmodesmus subspicatus was tested over a period of 72 hours according to OECD TG 201. Five concentrations ranging from 6.25 to 100 mg/L (nominal) were tested. The results of this study show that the test substance dodecanedioic acid induced inhibition of algal growth from 16.6 mg/L (measured) upwards with an EC50 (72h) for growth rate of > 38.6 mg/L (geometric mean) and a NOEC of 11.1 mg/L (measured).
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 38.6 mg/L
Additional information
No measured data was available regarding the toxicity of Corfree® M1 to aquatic plants. Using The toxicity of the read across chemical, dodecanedioic acid, the ErC50 (72 h) based on measured concentrations was determined as > 38.6 mg/L, indicating that the test substance does not pose a significant hazard to algae. The > 38.6 mg/L ErC50 (72 h) represents a value in excess of the substance's solubility in water.
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