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EC number: 203-127-1 | CAS number: 103-60-6
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Readily biodegradable (98% degradation after 28 days), OECD 301 F, Rudio (1994).
Readily biodegradable (64% degradation after 29 days), OECD 301 B, EU Method C.4 - C, Müller (1993).
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
The key study (Rudio, 1994) determined the biodegradability of the test material in line with GLP and the standardised guideline OECD 301 F. Measuring the oxygen consumption of the micro-organisms in the inoculum treated with the test material at 100 mg/L over 28 days. Under the conditions of the test, oxygen consumption indicated that the test material underwent 98% biodegradation after 28 days, where 90% degradation was achieved at the end of the 10-day window. The test material was therefore, considered to be readily biodegradable. The results obtained from the toxicity control showed that the test material did not inhibit the biodegradation of the inoculum. The study was performed to a high standard, and accordingly was assigned a reliability score of 1 in line with the principles for assessing data quality as defined in Klimisch (1997).
A further study (Müller, 1993) was provided as supporting data, where the biodegradability of the test material was determined in accordance with standardised guidelines OECD 301 B and EU Method C.4 -C in a carbon dioxide evolution test. The degradation rate of the test material during the test period of 29 days was reported to be 64%, and therefore the test material is considered to be readily biodegradable. This study was conducted to standardise guidelines and in accordance with GLP, however incomplete reporting meant that the study was assigned a reliability score of 2 in line with Klimisch (1997).
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