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EC number: 203-127-1
CAS number: 103-60-6
Table 1: Results
A maximisation test was conducting to determine the skin sensitisation
potential of the test material in line with the method described in the
Journal of Investigative Dermatology, Volume 47, No. 5; 1966 p 393-409.
During the test, the test material was applied under occlusion to sites
on the volar forearms of 25 healthy male volunteers, for five 48 hour
periods administered on alternate days. The patch sites were pre-tested
for 24 hours with 5 % aqueous sodium lauryl sulfate under occlusion.
Following a 10 day rest period, challenge patches of the test material
were applied under occlusion to fresh sites for 48 hours. Challenge
applications were preceded by one hour applications of 10 % aqueous
sodium lauryl sulfate under occlusion. The challenge sites were read on
removal of the patch and 24 hours thereafter.
Before the maximisation test was conducted, the test material was
pre-tested on 5 subjects in order to determine whether sodium lauryl
sulfate pre-treatment was required. A patch of the test material was
applied to normal sites on the backs for 48 hours under occlusion. No
subject had any irritation from the test material and it was decided to
use sodium lauryl sulfate as a pre-treatment in the test.
Under the conditions of the study there were no instances of contact
sensitisation from the test material during the maximisation test. It is
therefore considered unlikely that the test material is a skin
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