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EC number: 202-617-2
CAS number: 97-90-5
Summary of Analytical
value of all measured samples per treatment group
RSD: relative standard deviation per treatment group
n: number of analysed samples
n.a.: not applicable In
the freshly prepared test media 86 % of the nominal test concentrations
were found (average from all test concentrations equal and higher than
decrease of test item concentration was determined during the test
medium renewal periods of 48 and 72 hours. Therefore, the biological
results are related to geometric mean values.
The 21-day-chronic toxicity of to Daphnia magna STRAUS (Clone 5)
was studied under semi-static conditions. Daphnids were
exposed to control, and test chemical at measured concentrations of
0.158, 0.49, 1.58, 5.05 and 23.1 mg/L (geometric mean). The 21 day EC50based
on reproductive effects was > 5.05 mg a.i./L. The 21-day NOEC based on
reproductive effects was 5.05 mg a.i./L (the highest test
concentration with no significant reduction of the reproductive
output). There was no reproductive output at the highest concentration
The first brood was released till day 8 to 9 by all parent
animals of the control and the concentration levels except the highest
This study is classified as acceptable and satisfies the
guideline requirements for a chronic toxicity study with freshwater
Test Organism Age: Daphnia magna, 1.75 hr to 18 hr old
Test Type: semi-static, closed system
NOEC(reproduction): 5.05 mg a.i./L
LOEC(reproduction): 23.1 mg a.i./L
Endpoint(s) Effected: reproductive output, IR
long-term study in freshwater invertebrates is available for
The long term toxicity of the substance to Daphnia magna
has been evaluated in a 21 day semi-static reproductive toxicity test
according to OECD guideline 211 and EU method C.20.
were exposed to control and test chemical at measured concentrations of
0.32, 1.0, 3.2, 10 and 32 mg/L nominal corresponding to 0.158, 0.49,
1.58, 5.05 and 23.1 mg/L geometric mean measured concentrations.
The 21-day EC10 was found to be 7.22 mg/l (based on
reproduction) and the 21-day NOEC was 5.05 mg/l (based on reproduction
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