Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-617-2
CAS number: 97-90-5
Immobilization Rates in the Definitive Test after 24 and 48 h of
Exposure (n = 20, divided into 4 replicates with 5 daphnids each)
Concentrations in the test solutions were within +/- 20% of the nominal
values throughout the test and the control sample from time 0 confirmed
that the test item concentration was below the limit of detection. Therefore,
toxicity results were based on nominal concentrations.
Measured Concentration (mg/l)
0 BLD (nc) ns ns
13.2 12.8 (97) 12.4 (94) 12.1 (92)
19.8 19.3 (97) 18.9 (95) 18.3 (93)
29.6 28.6 (97) 27.2 (92) 27.1 (92)
44.4 43.9 (99) 42.4 (96) 41.8 (94)
66.7 64.2 (96) 62.7 (94) 61.1 (92)
100 96.1 (96) 94.9 (95) 93.0 (93)
(#) represent percentages of the nominal concentration
BLD = Below Limit of Detection
nc: not calculated
ns: not sampled
Ethylene glycol dimethacrylate
MV = Mean value
highest concentration resulting in no immobilization (NOEC) at 48 hours
was 13.2 mg/l.
The lowest concentration resulting in 100% immobilization at 48 hours
The EC50 at each of the observation times was as follows:
Time (h) EC50
confidence limits (mg/l)
66.7 and 100 NA
48 44.9 39.1
NA: Not applicable
The 48–hr-acute toxicity of Ethylene glycol dimethacrylate to
Daphnia magna straus was studied under static conditions according to
OECD 202. Daphnids were exposed to control, 13.2, 19.8, 29.6, 44.4,
66.7 and 100 mg/L (nominal) of the test chemical for 48 hr.
The concentrations of Ethylene glycol dimethacrylate were
analysed by HPLC with UV detection at 200 nm. The recoveries of
Ethylene glycol dimethacrylate in the test solutions were determined
to be within the acceptable limits.
The water quality parameters (pH and dissolveed oxygen) were
measured at 0 and 48 hours and determined to be within the acceptable
The 48– hour EC50was detemined to be 44.9 mg
a.i./L. The 48– hr NOEC based on immobilization/sublethal adverse
effects was determined to be 13.2 mg a.i./L.
This study is classified as acceptable and satisfies the
guideline requirements for an acute toxicity study with freshwater
Test Organism Age: Daphnia magna Straus, less than 24 hours old
Test Type: static, no aeration during the test period
NOEL: 13.2 mg a.i./L
EC50: 44.9 mg a.i./L 95% C.I.:
39.1 - 51.6 mg a.i./L
Endpoint(s) Effected: immobilisation
NOTE: Any of data in this dataset are disseminated by the
European Union on a right-to-know basis and this is not a publication
in the same sense as a book or an article in a journal. The right of
ownership in any part of this information is reserved by the data
owner(s). The use of this information for any other, e.g. commercial
purpose is strictly reserved to the data owners and those persons or
legal entities having paid the respective access fee for the intended
The acute toxicity of the substance was tested in a 48-h exposure test
in Daphnia magna according to OECD guideline 202.
The 48h-EC50 was found to be 44.9 mg/l..
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again