Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 202-617-2 | CAS number: 97-90-5
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- other: case report
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study well documented, meets generally accepted scientific principles, acceptable for assessment.
Data source
Reference
- Reference Type:
- publication
- Title:
- Burning mouth syndrome: A possible etiologic role for local contact hypersensitivity
- Author:
- Dutrée-Meulenberg R.O.G.M., Kozel M.M.A., Van Joost Th.
- Year:
- 1 992
- Bibliographic source:
- Journal of the American Academy of Dermatology 26: 935 - 940
Materials and methods
- Type of study / information:
- human - skin sensitization, case reports
- Endpoint addressed:
- skin sensitisation
Test guideline
- Qualifier:
- no guideline available
Test material
- Reference substance name:
- Ethylene dimethacrylate
- EC Number:
- 202-617-2
- EC Name:
- Ethylene dimethacrylate
- Cas Number:
- 97-90-5
- Molecular formula:
- C10H14O4
- IUPAC Name:
- 2-[(2-methylprop-2-enoyl)oxy]ethyl 2-methylprop-2-enoate
- Test material form:
- liquid
Constituent 1
Method
- Details on study design:
- 22 patients (19 women and 3 men) classified with the burning mouth syndrome (BMS) were patch tested with a standard routine series and a
standardized denture-dental ((meth)acrylate and metal) series.
Results and discussion
- Results:
- Twenty of the 22 patients wore a complete or partial denture. None of the 22 patients showed a positive reaction to the tested methacrylates
(Methyl methacrylate, Ethyl methacrylate, 2-Hydroxyethyl methacrylate, 2-Hydroxypropyl methacrylate, Ethylene glycol dimethacrylate 2 % in pet.).
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
