Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 267-051-0
CAS number: 67774-74-7
Table 1: Skin sensitization results
at 48 hrs
5% Right flank back
10% Right flank front
5% Right flank front
10% Right flank back
* - Dryness
C - Scratches
F - Redness
O – Hardening
A GPMT was performed in accordance with OECD
TG 406 and GLP to examine the potential of the test substance for
causing sensitization to skin. Groups of 20 female guinea pigs were
exposed by injection to 20 and 40 % test substance. One week later, they
were exposed dermally to a solution of 50 % test substance. The first
challenge was 14 days later, and the animals were exposed to 20 % test
substance dermally. One week later, a second challenge was done, in
which the animals were exposed to 5 and 10 % test substance dermally.
Animals were scored for skin irritation at 24, 48, and 72 hours after
the last challenge. The 48 hour reading was used to determine
sensitization. No signs of dermal irritation were seen at this reading.
The test substance in not sensitizing to skin.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Niniejsza strona używa plików cookies, aby zapewnić optymalne korzystanie z naszych stron internetowych.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again