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EC number: 267-051-0
CAS number: 67774-74-7
Table 1. Immobilized daphnids at 48
hrs – LAB
This study determined the short-term
toxicity of linear alkyl benzenes to Daphnia magna. The study was
conducted according to EU method C.2 guideline and compliance with GLP.
Daphnids were exposed to concentrations of 0, 12.5%, 25%, 50%, 75%, and
100% saturated test solution for 48 hrs. At the end of this period, the
daphnids were observed for mobility. Though immobilized daphnids were
seen at 4 test concentrations, there was no dose-related increase in
immobilization, nor was the number of immobilized daphnids significantly
increased over negative controls. Based on the findings, the 48-h EC50
was determined to be > 0.041 mg/L. This concentration is greater than
the water solubility for the test substance.
A 48-hour short-term toxicity test of the
test subtsance to freshwater invertebrate (Daphnia magna) was
conducted according to EU
method C.2. The LC50 based on
mortality was determinded to be > 0.041 mg/L.
The key study determined the
short-term toxicity of LAB to Daphnia magna. A test solution was
prepared, without use of solvent, to reach the solubility concentration
(0.041 mg/L). Daphnids were then exposed to concentrations of 0, 12.5%,
25%, 50%, 75%, and 100% of the saturated test solution for 48 hours. At
the end of this period, the daphnids were observed for mobility. Though
immobilized daphnids were seen at four test concentrations, there was no
dose-responsive increase in immobilization, nor was the number of
immobilized daphnids significantly increased over the negative controls.
Therefore, the 48-hr EC50
is > 0.041 mg/L (> 41 µg/L), which is greater than the
limits of water solubility for the test substance.
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