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EC number: 203-865-4
CAS number: 111-40-0
40% of diethylene triamine
15 min exposure:
1 animal without findings, one animal visible erythema
5 min exposure: without findings
1 min exposure: without findings
100% of diethylene triamine:
15 minutes exposure:
1st animal: upon substance removal very strong reddening with begining
necrosis. On day 1 greyish-brownish necrosis; on day 2 leather-like
blackish-brown crust-formation with remaining deep scar 3 weeks later
2nd animal: blackish-brown necrosis, bleeding, marginal red swelling
5 min of exposure:
1st animal: upon substance removal: reddening, spotted necrosis; on day
1 grey-brownish necrosis; on day 2 leather-like blackish-brown crust
formation with remaining deep deep scar 3 weeks latter.
2nd animal ; upon substance removal; Tan necrosis, bleeding, marginal
red swellling; on day 1 anaemic necrosis with marginal reddening; 8 day
hard crust formation with remainning scar after 3 weeks
1 min of exposure: upon substance removal slight reddening, partly
necrotic wtih marginal reddening; on day 1 slight reddening and pea
sized necrosis; On day 2 spotted reddening with pea-sized necrosis; on
day 8 spotted crusts with remaining scars.
The skin irritation potential of DETA was examined. A 15 minute
exposure to DETA resulted in necrosis in two of two rabbits.
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