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EC number: 203-865-4
CAS number: 111-40-0
In a growth inhibition test with Pseudokirchnerella subcapitata, the 72-hour ErC50 for diethylene triamine was 1164 mg/L. The 72-hour NOEC for diethylene triamine was determined to be 10 mg/L.
A total of four algal studies were listed under this endpoint, however
three of these studies were assigned a Kilimsch score of 4 based on the
unavailability of detailed study methodologies. One
toxicity study with the green algae,Pseudokirchnerella subcapitata,was
available for review and was found to be of good quality and reliable
for use in the risk assessment process. This study measured both growth
rate (r) and biomass (b) as indicators of growth
inhibition over 72 hours of exposure. The
72-hour NOEC with P. subcapitata was 10 mg/L diethylene triamine. The
72-hour EbC50 (based on biomass) and the 72-hour ErC50
(based on growth rate) were reported as 187 and 1164 mg/L diethylene
triamine, respectively. Since the use of the average
specific growth rate for estimating toxicity is scientifically preferred
(OECD 201, 2006), the 72-hour NOEC and ErC50 of 10 and 1164 mg/L
diethylene triamine were selected as the key parameters for this
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